Results 31 to 40 of about 218,644 (293)

The Effects of Tenascin C Knockdown on Trabecular Meshwork Outflow Resistance [PDF]

Investigative Opthalmology & Visual Science, 2013
Tenascin C (TNC) is a matricellular glycoprotein whose expression in adult tissue is indicative of tissue remodeling. The purpose of the current study was to determine the localization of TNC in trabecular meshwork (TM) tissue and to analyze the effects of TNC on intraocular pressure (IOP).Human TM frontal sections were immunostained with anti-TNC and ...
Kate E, Keller, Janice A, Vranka, Ramez I, Haddadin, Min-Hyung, Kang, Dong-Jin, Oh, Douglas J, Rhee, Yong-Feng, Yang, Ying Ying, Sun, Mary J, Kelley, Ted S, Acott   +9 more
openaire   +2 more sources

Permethrin resistance in Aedes aegypti: Genomic variants that confer knockdown resistance, recovery, and death

PLOS Genetics, 2021
Pyrethroids are one of the few classes of insecticides available to controlAedes aegypti, the major vector of dengue, chikungunya, and Zika viruses. Unfortunately, evolving mechanisms of pyrethroid resistance in mosquito populations threaten our ability to control disease outbreaks.
Karla Saavedra-Rodriguez, Corey L. Campbell, Saul Lozano, Patricia Penilla-Navarro, Alma Lopez-Solis, Francisco Solis-Santoyo, Americo D. Rodriguez, Rushika Perera, William C. Black IV   +8 more
openaire   +4 more sources

Characterizing Permethrin and Etofenprox Resistance in Two Common Laboratory Strains of Anopheles gambiae (Diptera: Culicidae)

Insects, 2018
Anopheles gambiae Giles (Diptera: Culicidae) is the most prolific malaria vector in sub-Saharan Africa, where widespread insecticide resistance has been reported. An.
Aaron D. Gross, Jeffrey R. Bloomquist
doaj   +1 more source

Insecticide resistance status in Anopheles gambiae in southern Benin. [PDF]

, 2010
BACKGROUND: The emergence of pyrethroid resistance in Anopheles gambiae has become a serious concern to the future success of malaria control. In Benin, the National Malaria Control Programme has recently planned to scaling up long-lasting insecticidal ...
Padonou, Gil, Akogbeto, Martin C, Imorou Yacoubou, Yacoubou, Imorou, Padonou Gil, Nicolas Moiroux, Gbenou Dina, N'Guessan, R., Dina Gbenou, Yacoubou Imorou, Gbenou, Dina, Alex Asidi, Yadouleton, A. W., Akogbeto, Martin, N'guessan Raphael, Yadouleton, Anges W, Gazard Kinde, Kinde Gazard, Bio-Banganna, S., Sahabi Bio-Banganna, Vincent Corbel, Bio-Banganna Sahabi, Corbel Vincent, Martin C Akogbeto, Asidi, A., Akogbeto, M. C., Gazard, Kinde, Gbenou, D., Raphael N'guessan, Bio-Banganna, Sahabi, Moiroux Nicolas, Yadouleton Anges W, Akogbeto Martin C, Anges W Yadouleton, Moiroux, Nicolas, Asidi, Alex, Padonou, G., N'guessan, Raphael, Yadouleton, Anges, Yacoubou, I., Gazard, K., Corbel, Vincent, Gil Padonou, Asidi Alex   +43 more
core   +1 more source

Molecular survey of knockdown resistance to pyrethroids in human scabies mites [PDF]

Clinical Microbiology and Infection, 2014
There are growing concerns about the emergence of resistance of Sarcoptes scabiei to permethrin and other pyrethroid derivatives. Sarcoptes scabiei mites collected from 40 patients visiting two hospitals near Paris, France, were genotypically characterized considering two parts of their voltage-sensitive sodium channel gene.
Andriantsoanirina, V., Izri, A., Botterel, F., Foulet, F., Chosidow, O., Durand, R.   +5 more
openaire   +2 more sources

Trends in the selection of insecticide resistance in Anopheles gambiae s.l. mosquitoes in northwest Tanzania during a community randomized trial of longlasting insecticidal nets and indoor residual spraying. [PDF]

, 2014
Anopheles gambiae s.l. (Diptera: Culicidae) in Muleba, Tanzania has developed high levels of resistance to most insecticides currently advocated for malaria control. The kdr mutation has almost reached fixation in An. gambiae s.s. in Muleba.
Wright, A, A. WRIGHT, J. MATOWO, M. ROWLAND, Kisinza, W, Kavishe, R, N. PROTOPOPOFF, Kitau, J, I. KLEINSCHMIDT, Matowo, J, Rowland, M, R. KAAYA, R. KAVISHE, W. KISINZA, Mosha, F, J. KITAU, Kaaya, R, Kleinschmidt, I, F. MOSHA, Protopopoff, N   +19 more
core   +1 more source

Knockdown resistance in pyrethroid-resistant horn fly (Diptera: Muscidae) populations in Brazil

Revista Brasileira de Parasitologia Veterinária, 2009
To investigate the kdr (knockdown resistance) resistance-associated gene mutation and determine its frequency in pyrethroid-resistant horn fy (Haematobia irritans) populations, a total of 1,804 horn flies of 37 different populations from all Brazilian regions (North, Northeast, Central-West, Southeast, and South) were molecular screened through ...
Sabatini, Gustavo A., Ribolla, Paulo E. M., Barros, Antonio T. M., Guerrero, Felix D., Schumaker, Terezinha T. S.   +4 more
openaire   +6 more sources

Knockdown of POLA2 increases gemcitabine resistance in lung cancer cells [PDF]

BMC Genomics, 2016
Gemcitabine is used as a standard drug treatment for non-small cell lung cancer (NSCLC), but treatment responses vary among patients. Our previous studies demonstrated that POLA2 + 1747 GG/GA single nucleotide polymorphism (SNP) improves differential survivability and mortality in NSCLC patients.
Koh, V, Kwan, H.Y, Tan, W.L, Mah, T.L, Yong, W.P   +4 more
openaire   +2 more sources

Insecticide resistance and genetic variability in natural populations of Aedes (Stegomyia) aegypti (Diptera: Culicidae) from Colombia

Zoologia (Curitiba), 2015
Mosquito control prevails as the most efficient method to protect humans from the dengue virus, despite recent efforts to find a vaccine for this disease. We evaluated insecticide resistance and genetic variability in natural populations of Aedes aegypti
Oscar A. Aguirre-Obando, Ana C. Dalla Bona, Jonny E. Duque L., Mário A. Navarro-Silva   +3 more
doaj   +1 more source

Status of insecticide susceptibility in Anopheles gambiae s.l. from malaria surveillance sites in The Gambia. [PDF]

, 2009
BACKGROUND: Vector control is an effective way of reducing malaria transmission. The main vector control methods include the use of insecticide-treated bed nets and indoor residual spraying (IRS).
Betson, M, Betson, Martha, Awolola, Taiwo Samson, Awolola, T S, Natural History Museum, Jawara, Musa, LSHTM, Jawara, M, Malaria Research Programme, Gambia, Nigerian Institute of Medical Research, Martha Betson, Taiwo Samson Awolola, Musa Jawara   +12 more
core   +1 more source