Results 51 to 60 of about 218,644 (293)

Relationship between long non-coding RNA PCAT-1 expression and gefitinib resistance in non-small-cell lung cancer cells

Respiratory Research, 2021
Background Gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, has been used as first-line treatment for advanced non-small-cell lung cancer (NSCLC). However, during treatment, cancer cells often develop resistance to gefitinib, the
Shaojia Wang, Chao Liu, Qing Lei, Zhengwei Wu, Xiangshuai Miao, Debing Zhu, Xu Yang, Na Li, Mingwei Tang, Yan Chen, Weiwei Wang   +10 more
doaj   +1 more source

A multiplex PCR for detection of knockdown resistance mutations, V1016G and F1534C, in pyrethroid-resistant Aedes aegypti [PDF]

Parasites & Vectors, 2017
La mutation du gène du canal sodique voltage-dépendant (VGSC), ou gène de résistance à la détonation (kdr), est un mécanisme de résistance important des moustiques vecteurs de la dengue Aedes aegypti contre les pyréthroïdes. Dans de nombreux pays d'Asie, une substitution de la valine en glycine (V1016G) et une substitution de la phénylalanine en ...
Jassada Saingamsook, Atiporn Saeung, Jintana Yanola, Nongkran Lumjuan, Catherine Walton, Pradya Somboon   +5 more
openaire   +4 more sources

Resistance status of Anopheles gambiae (s.l.) to four commonly used insecticides for malaria vector control in South-East Nigeria

Parasites & Vectors, 2020
Background Progress made in the control of malaria vectors globally is largely due to the use of insecticides. However, success in the fight against malaria has slowed down or even stalled due to a host of factors including insecticide resistance.
Okechukwu Chukwuekezie, Emmanuel Nwosu, Udoka Nwangwu, Festus Dogunro, Cosmas Onwude, Nneka Agashi, Ebuka Ezihe, Clementina Anioke, Stephen Anokwu, Emelda Eloy, Peter Attah, Francis Orizu, Sylvester Ewo, Angela Okoronkwo, Anumba Joseph, Ijeoma Ikeakor, Sylvester Haruna, Virgile Gnanguenon   +17 more
doaj   +1 more source

Knockdown times in a simple assay determination of insecticide resistance in malaria vectors

Transactions of The Royal Society of Tropical Medicine and Hygiene, 2021
Abstract Background Determining the insecticide resistance status of malaria vectors, particularly to insecticides used on mosquito nets, is important but is limited to a relatively small number of locations.
Jacques D Charlwood, Ayubo Kampango
openaire   +3 more sources

Challenges for Malaria Elimination in Zanzibar: Pyrethroid Resistance in Malaria Vectors and Poor Performance of Long-Lasting Insecticide Nets. [PDF]

, 2013
Long-lasting insecticide treated nets (LLINs) and indoor residual house spraying (IRS) are the main interventions for the control of malaria vectors in Zanzibar.
Devine, Gregor J, Maureen Coetzee, Haji, Khamis A, Smith, Stephen, Ali, Abdullah S, Coetzee, Maureen, Silas Majambere, Khamis A Haji, Stephen Smith, Khatib, Bakari O, Gregor J Devine, Bakari O Khatib, Abdullah S Ali, Majambere, Silas   +13 more
core   +1 more source

Insecticide resistance in Culex quinquefasciatus from Zanzibar: implications for vector control programmes. [PDF]

, 2012
\ud \ud Zanzibar has a long history of lymphatic filariasis (LF) caused by the filarial parasite Wuchereria bancrofti, and transmitted by the mosquito Culex quinquefasciatus Say.
Ali, Abdullah S., Mohammed, Khalfan, Khalfan Mohammed, Khatib, Bakari O., Machin, Camille, Kelly-Hope Louise A, Louise A Kelly-Hope, Ali, Abdullah S, Jones, Chris, Mcha Juma, Mohammed Khalfan, Khatib, Bakari O, Juma Mcha, Ranson, Hilary, McHa, Juma, Jones Christopher M, Abdullah S Ali, Kelly-Hope, Louise, Ranson, Hilary; id_orcid, Silas Majambere, Majambere Silas, Christopher M Jones, Bakari O Khatib, Kelly-Hope, Louise A, Machin Camille, Ali Abdullah S, Camille Machin, Jones, Christopher M, Khatib Bakari O, Majambere, Silas, Hilary Ranson, Ranson Hilary   +31 more
core   +1 more source

Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control?

, 2011
The use of pyrethroid insecticides in malaria vector control has increased dramatically in the past decade through the scale up of insecticide treated net distribution programmes and indoor residual spraying campaigns.
Jonathan Lines, Ranson, H., Nicolas Moiroux, Ranson, Hilary; id_orcid, Lines, J., N'Guessan, R., Nkuni, Zinga, Zinga Nkuni, Moiroux, Nicolas, N'guessan, Raphael, Ranson, Hilary, Lines, Jonathan, Nkuni, Z., Hilary Ranson, Vincent Corbel, Corbel, Vincent, N’guessan, Raphael, Raphael N’Guessan   +17 more
core   +1 more source

First Report of the L925I kdr Mutation Associated with Pyrethroid Resistance in Genetically Distinct Triatoma dimidiata, Vector of Chagas Disease in Mexico

Tropical Medicine and Infectious Disease
Triatoma dimidiata is a widely distributed vector of Trypanosoma cruzi in Mexico and Central America, found across a range of habitats from sylvatic to domestic.
Mario C. Saucedo-Montalvo, Jesus A. Davila-Barboza, Selene M. Gutierrez-Rodriguez, Beatriz Lopez-Monroy, Susana Favela-Lara, Iram P. Rodriguez-Sanchez, Guadalupe del C. Reyes-Solis, Cristina Bobadilla-Utrera, Adriana E. Flores   +8 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The activity of the pyrrole insecticide chlorfenapyr in mosquito bioassay: towards a more rational testing and screening of non-neurotoxic insecticides for malaria vector control. [PDF]

, 2015
BACKGROUND: The rapid selection of pyrethroid resistance throughout sub-Saharan Africa is a serious threat to malaria vector control. Chlorfenapyr is a pyrrole insecticide which shows no cross resistance to insecticide classes normally used for vector ...
Franklin W Mosha, Mark W Rowland, Jones, Rebecca, Malone, David, Kitau, Jovin, Jovin Kitau, David Malone, Ngufor, Corine, Rowland, Mark W, Richard M Oxborough, Mosha, Franklin W, Corine Ngufor, Oxborough, Richard M, N'Guessan, Raphael, Rebecca Jones, Raphael N’Guessan   +15 more
core   +1 more source