Results 71 to 80 of about 218,644 (293)

Emergence of knock-down resistance in the Anopheles gambiae complex in the Upper River Region, The Gambia, and its relationship with malaria infection in children

Malaria Journal, 2018
Background Insecticide resistance threatens malaria control in sub-Saharan Africa. Knockdown resistance to pyrethroids and organochlorines in Anopheles gambiae sensu lato (s.l.) is commonly caused by mutations in the gene encoding a voltage-gated sodium ...
Anne L. Wilson, Margaret Pinder, John Bradley, Martin J. Donnelly, Majidah Hamid-Adiamoh, Lamin B. S. Jarju, Musa Jawara, David Jeffries, Ballah Kandeh, Emily J. Rippon, Kolawole Salami, Umberto D’Alessandro, Steven W. Lindsay   +12 more
doaj   +1 more source

Silencing MED1 sensitizes breast cancer cells to pure anti-estrogen fulvestrant in vitro and in vivo. [PDF]

PLoS ONE, 2013
Pure anti-estrogen fulvestrant has been shown to be a promising ER antagonist for locally advanced and metastatic breast cancer. Unfortunately, a significant proportion of patients developed resistance to this type of endocrine therapy but the molecular ...
Lijiang Zhang, Jiajun Cui, Marissa Leonard, Kenneth Nephew, Yongquan Li, Xiaoting Zhang   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Field efficacy of pyrethroid treated plastic sheeting (durable lining) in combination with long lasting insecticidal nets against malaria vectors. [PDF]

, 2010
BACKGROUND: Insecticide treated plastic sheeting (ITPS), sometimes known as durable lining, has potential as a long-lasting insecticidal surface for malaria vector control when used as lining for interior walls and ceilings inside the home.
Chandre Fabrice, Mark Rowland, N'Guessan Raphael, Dabire, R. K., Irish Seth R, Roch K Dabire, N'Guessan, R., Dabire Roch K, Hougard, Jean-Marc, Djogbenou Luc S, Irish, Seth R, Irish, S. R., Rowland Mark, Hougard Jean-Marc, Chandre, Fabrice, Rowland, Mark, Luc S Djogbenou, Djogbenou, Luc S, Fabrice Chandre, Seth R Irish, Rowland, M., Jean-Marc Hougard, N'guessan, Raphael, Raphael N'Guessan, Dabire, Roch K, Djogbenou, L. S.   +25 more
core   +1 more source

Knockdown resistance mutations contributing to pyrethroid resistance in Aedes aegypti population, Saudi Arabia

Eastern Mediterranean Health Journal, 2019
Dengue is endemic in Saudi Arabia especially in Jeddah, Makkah, Asir, and Jazan areas where pyrethroids are widely used to control the vector, Aedes aegypti. Resistance of Ae. aegypti to pyrethroid insecticides has been reported from most of these areas.The present study was carried out in Jazan region in south-west Saudi Arabia to explore the ...
Ommer, Dafalla, Adel, Alsheikh, Waheed, Mohammed, Khalid, Shrwani, Feras, Alsheikh, Yahya, Hobani, Elsiddig, Noureldin   +6 more
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Quick knockdown results in high mortality: is this theory correct? A case study with phosphine and the red flour beetle [PDF]

, 2023
BACKGROUND The fumigant phosphine is used all over the world for disinfestation of stored grains and commodities. Adults of 23 different populations of Tribolium castaneum from 10 different countries, were evaluated for phosphine resistance using a ...
Dionysis Bochtis, Nakas, Christos T., Christos G. Athanassiou, Sakka, Maria K, Maria K. Sakka, Christos T. Nakas, Bochtis, Dionysis, Athanassiou, Christos G   +7 more
core   +1 more source

The polymorphism and geographical distribution of knockdown resistance of adult Anopheles sinensis populations in eastern China

Malaria Journal, 2019
Background Anopheles sinensis is one of the major malaria vectors in China and other southeast Asian countries, including Vietnam, Cambodia, Thailand.
Wei-Long Tan, Chun-Xiao Li, Rui-Chen Lv, Yan-De Dong, Xiao-Xia Guo, Dan Xing, Ming-hao Zhou, Yan Xu, Hong-liang Chu, Gang Wang, Chang-qiang Zhu, Jun Sun, Tong-Yan Zhao   +12 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Distribution and spread of pyrethroid and DDT resistance among the Anopheles gambiae complex in Tanzania.

, 2013
The development of insecticide resistance is a threat to the control of malaria in Africa. We report the findings of a national survey carried out in Tanzania in 2011 to monitor the susceptibility of malaria vectors to pyrethroid, organophosphate ...
Kisinza, W, McElroy, PD, Minja, J, Tungu, P, Rowland, M, Kafuko, J, Kulkarni, M, Kabula, B, Malima, R, Mosha, F, Magesa, S, Wililo, R, Ramsan, M, Protopopoff, N   +13 more
core   +1 more source