Results 11 to 20 of about 739,130 (263)

CAF1-knockout mice are more susceptive to lipopolysaccharide-induced acute lung injury

Journal of Inflammation Research, 2016
Jia-Xin Shi,1 Jia-Shu Li,1 Rong Hu,1 Xiao-Min Li,2 Hong Wang3 1Department of Respiratory Medicine, Lianyungang First People’s Hospital, Affiliated Hospital of Xuzhou Medical University, Affiliated Hospital of the Clinical Medical School of Nanjing ...
Shi JX, Li JS, Hu R, Li XM, Wang H
doaj   +1 more source

The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system [PDF]

, 2008
INTRODUCTION: Ghrelin and cannabinoids stimulate appetite, this effect possibly being mediated by the activation of hypothalamic AMP-activated protein kinase (AMPK), a key enzyme in appetite and metabolism regulation. The cannabinoid receptor type 1 (CB1)
Judith Harvey-White, Francesca Lolli, Farkas, I., Amin, F., Mirjam Christ-Crain, Kola, Blerina, Fekete, Csaba, George Kunos, Kola, B., Faisal Amin, A. B. Grossman, M. Korbonits, Blerina Kola, Liposits, Zsolt, G. Kunos, Ashley B Grossman, B. Kola, Amin, F, Gábor Wittmann, Kunos, George, Christ-Crain, M, Farkas, Imre, Lolli, F, Zsolt Liposits, Lolli, F., F. Amin, Farkas, I, Christ-Crain, M., Korbonits, M., I. Farkas, Grossman, AB, C. Fekete, Kola, B, Harvey-White, J., Wittmann, Gábor, Korbonits, Márta, G. Wittmann, Harvey-White, J, Fekete, C, Harvey-White, Judith, Márta Korbonits, Imre Farkas, Liposits, Z, Z. Liposits, Grossman, Ashley B., Ashley B. Grossman, Wittmann, G., Christ-Crain, Mirjam, Amin, Faisal, Lolli, Francesca, Liposits, Z., M. Christ Crain, J. Harvey White, Fekete, C., Korbonits, M, Kunos, G., Csaba Fekete, Grossman, A. B., Kunos, G, Wittmann, G   +59 more
core   +3 more sources

Abundant Neural circRNA Cdr1as Is Not Indispensable for Retina Maintenance

Frontiers in Cell and Developmental Biology, 2020
Cdr1as is the abundant circular RNA (circRNA) in human and vertebrate retinas. However, the role of Cdr1as in the retina remains unknown. In this study, we aimed to generate a Cdr1as knockout (KO) mouse model and investigate the retinal consequences of ...
Xue-Jiao Chen, Meng-Lan Li, Ya-Han Wang, Hao Mou, Zhen Wu, Siqi Bao, Ze-Hua Xu, Hang Zhang, Xiao-Yun Wang, Chang-Jun Zhang, Xiangyang Xue, Zi-Bing Jin, Zi-Bing Jin, Zi-Bing Jin   +13 more
doaj   +1 more source

Mu-opioid receptor knockout mice show diminished food-anticipatory activity [PDF]

, 2004
We have previously suggested that during or prior to activation of anticipatory behaviour to a coming reward, mu-opioid receptors are activated. To test this hypothesis schedule induced food-anticipatory activity in mu-opioid receptor knockout mice was ...
van den Bos, Ruud, Schuller, Alwin G, Sub Neurobiologie van gedrag, Kas, Martien J H, Spruijt, Berry M, Sub Animal Ecology, Bedrijfsvoering, Lesscher, Heidi M B, Lubbers, Marianne, Hillebrand, Jacquelien J G, Pintar, John E, Baars, Annemarie M   +11 more
core   +1 more source

Prediction of SMAD7 knockout

, 2022
MAD7 knockout prediction by reducing the parameter of SMAD dependant feedback induction in the internalization model to 30 \% of its original value in case of a single stimulation with 100 pM TGF-β.
Lukas-Malte Bammert (11998654), Alexander Lower (11998662), Niklas Kolbe (11998394), Stefan Legewie (65841), Mária Lukáčová-Medviďová (11998661), Lorenz Hexemer (11998718)   +5 more
core   +2 more sources

Correction of the iron overload defect in beta-2-microglobulin knockout mice by lactoferrin abolishes their increased susceptibility to tuberculosis. [PDF]

, 2002
As a resident of early endosomal phagosomes, Mycobacterium tuberculosis is connected to the iron uptake system of the host macrophage. beta-2-microglobulin (beta2m) knockout (KO) mice are more susceptible to tuberculosis than wild-type mice, which is ...
Friedrich Priem, Priem, F, Kaufmann, Stefan HE, Collins, Helen L, Ulrich E. Schaible, Kaufmann, S H E, Schaible, Ulrich E, Helen L. Collins, Collins, H L, Priem, Friedrich, Stefan H.E. Kaufmann, Schaible, U E   +11 more
core   +1 more source

Analysis of the Role of the Mc4r System in Development, Growth, and Puberty of Medaka

Frontiers in Endocrinology, 2019
In mammals the melanocortin 4 receptor (Mc4r) signaling system has been mainly associated with the regulation of appetite and energy homeostasis. In fish of the genus Xiphophorus (platyfish and swordtails) puberty onset is genetically determined by a ...
Ruiqi Liu, Masato Kinoshita, Mateus C. Adolfi, Manfred Schartl, Manfred Schartl, Manfred Schartl   +5 more
doaj   +1 more source

"Plasmodium falciparum" transfection technology for the analysis of "var" gene regulation and knockout investigation [PDF]

, 2007
Malaria is an infectious disease caused by protozoans of the genus Plasmodium, which are injected by the bite of an infected female Anopheles mosquito during a blood meal. Out of the four species that infect humans, P. falciparum is the most important.
Bopp, Selina Elisabeth Ruth
core   +1 more source

Selenoprotein F Knockout Caused Glucose Metabolism Disorder in Young Mice by Disrupting Redox Homeostasis

Antioxidants, 2022
Selenoprotein F (SELENOF) might play an important role in maintaining human health since an increasing number of studies have linked SELENOF deficiency to various pathologies such as cancer and neurodegeneration.
Min Li, Yun Zhang, Jun Zhou, Hongmei Liu
doaj   +1 more source

The apoptotic role of metacaspase in Toxoplasma gondii

Frontiers in Microbiology, 2016
Toxoplasma gondii is a major opportunistic pathogen that spreads in a range of animal species and human beings. Quite a few characterizations of apoptosis have been identified in T.
Qun eLiu, Muzi eLi, Hui eWang, Jing eLiu, Pan eHao, Lei eMa   +5 more
doaj   +1 more source