Results 71 to 80 of about 338,228 (246)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

VER, CONOCER, IMAGINAR: LA VISIÓN DE LA FUENTE Y LAS TRES DONCELLAS EN EL LIBER DIVINORUM OPERUM DE HILDEGARD DE BINGEN

open access: yesRevista Chilena de Literatura, 2006
En este trabajo se desarrollan algunos de los temas relacionados con la visión y los sentidos tomando como ejemplo unos de los textos visionarios de la tercera parte del Liber divinorum operum (LDO, III, 3) de Hildegard de Bingen, la religiosa alemana ...
María Eugenia Góngora
doaj  

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Knowing Apples

open access: yesSocieties, 2013
This essay employs a first-person fictional narrator to explore the nature of human-plant relations through the example of Thoreau’s Wild Apples and enacts the transformational process necessary to write in conjunction with non-conscious vegetal life by ...
Lorraine Shannon
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Opening Spaces of Possibility: The Enactive as a Qualitative Research Approach

open access: yesForum: Qualitative Social Research, 2002
In this jointly written article, reflexivity and subjectivity in qualitative research are addressed through an enactive view/approach incorporating embodied knowing.
Johnna Haskell   +2 more
doaj  

Knowing Ourselves

open access: yesCanadian Journal of Learning and Technology, 1983
None
Ken Osborne
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Knowing the Mississippi

open access: yesOpen Rivers, 2015
We asked a diverse group of river people to respond to the prompt “How did you come to know the Mississippi River? What does it mean, to you, to know the Mississippi River?” We present below a few of the responses, in no particular order.
Sharon Day, Bernard Williams, Christopher Morris, Conevery Bolton Valencius, Craig Colten
doaj   +1 more source

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