Results 41 to 50 of about 9,113,182 (295)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
پاکستان جرنل آف اسلامک فلاسفی, 2023 Bukhara, a historical city in Uzbekistan, Central Asia, has been a significant hub of human civilization for more than 2,500 years. This study reveals Bukhara's diverse and intricate importance, emphasizing its exceptional role as a nexus for various ...
Dr. Muhammad Umar Riaz Abbasi
doaj
Indigenous Knowledge and the Convention on Biological Diversity
The Australian Journal of Indigenous Education, 2008 Australia is rich in biological diversity and Indigenous Australians hold substantial knowledge about how to care for and utilise a diverse range of plants and other biological elements which occur here.
Robynne Quiggin
doaj +1 more source
Resarch based links: knowledge diversity to solve productive problems [PDF]
Trilogía Ciencia Tecnología Sociedad, 2015 A characteristic of research at the university level is its universal approach which involves all areas of knowledge. The aim of this paper is to analyze how such diversity in research can be seen as a strength for linking academic work with the industry.
Carlos Bianchi, Claudia Cohanoff
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The Richness of Diversity in Knowledge Creation: An Interdisciplinary Overview
J. Univers. Comput. Sci., 2003 JUCS - Journal of Universal Computer Science Volume Nr.
Bonifacio, Matteo Salvatore, A. Molani
openaire +2 more sources
Gender differences in traditional knowledge of useful plants in a Brazilian community.
PLoS ONE, 2021 Genders differ in traditional ecological knowledge (TEK) about plants, but how gender influences TEK sharing is still poorly understood. Here, we examined how gender is associated with the diversity, transmission, and structure of TEK.
Fernanda Vieira da Costa +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Journal of Ethnobiology and Ethnomedicine, 2017 Background Diet and nutrition-related behaviours are embedded in cultural and environmental contexts: adoption of new knowledge depends on how easily it can be integrated into existing knowledge systems.
Bronwen Powell +3 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source