Results 81 to 90 of about 633,162 (316)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Acceptability of Interventions to Address Polypharmacy in Older Adult Outpatients: A Systematic Review and Meta‐Analysis

Health Science Reports
Background and Aims Interventions to address potentially inappropriate prescribing (PIP), where risks outweigh benefits, are effective but often not implemented due to barriers (e.g., patient, provider, systems).
Nav Persaud, Amal Rizvi, Aine Workentin, Becky Skidmore, Emily G. McDonald   +4 more
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Bias in machine learning applications to address non-communicable diseases at a population-level: a scoping review

BMC Public Health
Background Machine learning (ML) is increasingly used in population and public health to support epidemiological studies, surveillance, and evaluation.
Sharon Birdi, Roxana Rabet, Steve Durant, Atushi Patel, Tina Vosoughi, Mahek Shergill, Christy Costanian, Carolyn P. Ziegler, Shehzad Ali, David Buckeridge, Marzyeh Ghassemi, Jennifer Gibson, Ava John-Baptiste, Jillian Macklin, Melissa McCradden, Kwame McKenzie, Sharmistha Mishra, Parisa Naraei, Akwasi Owusu-Bempah, Laura Rosella, James Shaw, Ross Upshur, Andrew D. Pinto   +22 more
doaj   +1 more source

Knowledge Visualization: A Comparative Study between Project Tube Maps and Gantt Charts [PDF]

, 2005
This paper compares the effectiveness of the Project Tube Map and the Gantt Chart for interfunctional communication in large projects where different stakeholders are involved. Today, Gantt Charts are well known in project management. However, the use of
Smis, Matthias T. J., Rodgers, Peter, Burkhard, Remo Aslak, Stott, Jonathan, Meier, Michael   +4 more
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Regional Knowledge Maps - Potentials and Challenges

Proceedings of the International Conference on Knowledge Discovery and Information Retrieval and the International Conference on Knowledge Management and Information Sharing, 2013
Regional knowledge map is a tool recently demanded by some actors in an institutional level to help regional policy and innovation in a territory. Besides, knowledge maps facilitate the interaction between the actors of a territory and the collective learning.
Garcia-Alsina, Montserrat, Wartena, Christian, Lieberam-Schmidt, Sönke   +2 more
openaire   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Building multi-layer social knowledge maps with google maps API [PDF]

, 2012
Google Maps is an intuitive online-map service which changes people's way of navigation on Geo-maps. People can explore the maps in a multi-layer fashion in order to avoid information overloading.
Guerra, Julio, Liang, ME, Liang, Miner, Guerra, J, Brusilovsky, Peter, Brusilovsky, P   +5 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source