Results 61 to 70 of about 8,064,818 (293)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Retention of Aeronautical Knowledge [PDF]

, 2007
Pilots' retention of aeronautical knowledge learned during private pilot training was studied in four experiments. In the first experiment, ten questions from the FAA private pilot airplane knowledge test were administered to sixty pilots, yielding an average score of 74.8%.
Casner, Stephen M., Heraldez, Daniel, Jones, Karen M.   +2 more
openaire  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Integrating Basic Sciences into Dental Education: A Comparative Narrative Review of Curricular Approaches Across Different Countries

Dentistry Journal
Background/Objectives: Basic sciences form the conceptual foundation of dentistry, yet their delivery in dental curricula varies worldwide. As demographic shifts, growing healthcare complexity and scientific advances continue to reshape the dental ...
Ghazal Ek, Vår Kristidatter Syversen, Qalbi Khan, Tor Paaske Utheim, Amer Sehic   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Constructive Multi-Criteria Model to Support Organizational Knowledge Retention Management

, 2019
Paper describes a support model for the management of organizational knowledge ...
Ensslin, Leonardo, Mussi, Clarissa Carneiro, Fontana, Lydia Pereira Bez, Ensslin, Sandra Rolim, Dutra, Ademar   +4 more
core  

Predictors of retention in the ‘voluntary’ and ‘quasi-compulsory’ treatment of substance dependence in Europe [PDF]

, 2011
Background: Policies and practices related to the quasi-compulsory treatment (QCT) of substance-dependent offenders are currently implemented in many countries, despite the absence of reliable knowledge about significant predictors of treatment retention.
Michael Schaub, Oeuvray, K., Haug, Severin; https://orcid.org/, Werdenich, W, Haug, Severin, Irene Puppo, Oeuvray, K, Severin Haug, Stevens, A., Schaub, Michael, Santa Maria, A, Schaub, Michael P; https://orcid.org/, Neil Hunt, Kerrie Oeuvray, Trinkl, B, Santa Maria, Alberto, Alberto Santa Maria, Berto, D., Puppo, Irene, Werdenich, Wolfgang, McSweeney, Tim, Schaub, M., Kerschl, V., Werdenich, W., Oeuvray, Kerrie, Kerschl, V, Viktoria Kerschl, Kerschl, Viktoria, Uchtenhagen, Ambros, Daniele Berto, Ambros Uchtenhagen, Stevens, Alex, Hunt, Neil, Haug, S., Berto, Daniele, Berto, D, Tim McSweeney, Wolfgang Werdenich, Uchtenhagen, A., Hunt, N, Trinkl, Barbara, Santa Maria, A., Stevens, A, Alex Stevens, Barbara Trinkl, Puppo, I., Puppo, I, Trinkl, B., Hunt, N., McSweeney, T   +49 more
core   +1 more source

Evaluating learning methods to improve pharmacy students’ retention of nonsterile compounding skills

Advances in Biomedical and Health Sciences
Background: Compounding pharmacy is an essential component of pharmaceutical practice. With the implementation of compounding pharmacy, therapeutic needs are being met for prescriptions, including patients allergic to a specific excipient, adjusted ...
Karina Mendez Cordero, Cindy Ngoc Chau, Damianne Brand, Ayesha Rahman Ahmed   +3 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source