Results 81 to 90 of about 8,064,818 (293)

An analytic study of knowledge retention at different time intervals among junior residents following recapitulation of presented slides silently at the end of teaching session

Journal of Medical Education Development
Background & Objective: Facilitators commonly ponder how to effectively conclude a learning session, and there are no clear answers. This novel study analyzes the impact of silent recapitulation of presented slides at session end on immediate and short ...
Suman Chattopadhyay
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Affordances and Core Features of Successful Digital Courses Design in Higher Education

Open Praxis
In recent years, digital education has become a cornerstone of higher education, particularly following the rapid expansion of online learning during the COVID-19 pandemic.
Rouhollah Khodabandelou, Ahmed Mohamed Fahmy Yousef, Abdelrahman Elhaj   +2 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Knowledge retention process evaluation during soldiers’ rotation. [PDF]

, 2017
In today‘s dynamic, modern and knowledge-based Army individual soldiers knowledge became the basis for further development of the Army, so inevitably created the need for retention of individual soldiers knowledge in order to reuse it in the future to ...
Armalis, Ramūnas,
core   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Prevention, Retention & Contingency Development Reserve (PRCDR) summary of projects

, 2000
Title from covers of PDF documents (viewed June 21, 2006).; "The Institute for Local Government Administration and Rural Development (ILGARD) at Ohio University prepared this report for the Ohio Department of Job and Family Services in cooperation with ...
Ohio University. Institute for Local Government Administration and Rural Development.
core  

Leveling up in corporate training: Unveiling the power of gamification to enhance knowledge retention, knowledge sharing, and job performance. [PDF]

[EN] This paper extends the fast-growing research stream on gamification in corporate training by examining the impact of gamification on employees¿ knowledge retention, knowledge sharing, and job performance.
Micu, Angela Eliza, Juárez Varón, David, Capatina, Alexandru, Juarez-Varon, David, Micu, Adrian   +4 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source