Results 61 to 70 of about 913,222 (259)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Polytomous Knowledge Structures Based on Entail Relations

Mathematics
In knowledge structure theory (KST), an individual’s knowledge state represents the items that the individual can completely solve. Based on the differences in individuals’ latent cognitive competence, polytomous knowledge states can be used to partially
Zhaorong He
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Knowledge structures of scientific production on COVID-19 in the sphere of education: the case of publications indexed in the Web of Science during 2020. [PDF]

Qual Quant, 2022
Rodríguez-Sabiote C, Úbeda-Sánchez ÁM, Lorenzo-Quiles O, Álvarez-Rodríguez J.   +3 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Knowledge management framework (kmf) based on layers

Visión Electrónica, 2016
Research in the eld of Knowledge Management (KM) has grown in accumulation and importance in both the academic and business worlds. However, it has not properly established how and when a KM initiative should be implemented.
Juan C. Guevara B., Gloria A. Cavanzo N, Miguel Perez P   +2 more
doaj  

Conservazione e sicurezza strutturale nel patrimonio novecentesco: spunti di riflessione per un indirizzo normativo /

Restauro Archeologico
The verification of structural safety and the consolidation of 20th-century architecture in ‘mixed’ or reinforced concrete structures are complex issues in the current debate, partly because the regulatory instruments governing structural restoration ...
Adalgisa Donatelli
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

The relation between knowledge management strategies and organization structures [PDF]

مطالعات مدیریت بهبود و تحول, 2009
In this paper we exploring that how we can choose the best structure for an organization by using the concept of knowledge management also we examine the above issue in the an organization with organic structure (Leaming organization) and with stable ...
mir ali seyed naghavi
doaj