Results 151 to 160 of about 85,174 (277)

A Study on Undiagnosed Hypertension and Its Associated Factors among Adults Residing in a Rural Area of West Bengal

National Journal of Community Medicine, 2018
Background: Currently, hypertension is one of the important cause of cardiovascular morbidity and mortality worldwide.  Objective: To estimate the prevalence and determinants of undiagnosed hypertension in a rural area of West Bengal.
Nabanita Chakraborty, Asok K Mandal
doaj  

Klebsiella pneumoniae Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering

mBio, 2017
The emergence of Klebsiella pneumoniae carbapenemases (KPCs), β-lactamases that inactivate “last-line” antibiotics such as imipenem, represents a major challenge to contemporary antibiotic therapies.
M. D. Barnes, M. L. Winkler, M. Taracila, M. Page, E. Desarbre, B. Kreiswirth, R. Shields, M. Nguyen, C. Clancy, B. Spellberg, K. Papp-Wallace, R. Bonomo   +11 more
semanticscholar   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Klebsiella pneumoniae KPC: first isolations in Italy

, 2009
Klebsiella pneumoniae carbapenemase (KPC) was detected in two isolates of carbapenem-resistant K. pneumoniae in an italian teaching hospital. This is the first report of a KPC-producing isolates in our country.
Silvia Minelli, Marco Favaro, Maria Cristina Bossa, Loredana Sarmati, Anna Altieri, Cartesio Favalli, Silvia Natoli, Carla Fontana   +7 more
core   +1 more source

Clonal dissemination of Klebsiella pneumoniae ST258 harbouring KPC-2 in Argentina [PDF]

, 2011
The present work describes the abrupt emergence of Klebsiella pneumoniae carbapenemase (KPC) and characterizes the first 79 KPC-producing enterobacteria from Argentina (isolated from 2006 to 2010).
Faccone, Diego Francisco, N. Tijet, Petroni, Alejandro, Galas, M., Group, KPC, E. Albornoz, Faccone, Diego, F.G. Pasteran, C. Lucero, Tijet, N., Albornoz, Ezequiel, M. Galas, Pasteran, F. G., Galas, Marcelo F., M. Rapoport, KPC Group, R.G. Melano, D. Faccone, Lucero, Celeste, S.A. Gomez, Albornoz, Ezequiel Pablo, A. Petroni, Gomez, S.A., Pasteran, F.G., Melano, R.G., A. Corso, Rapoport, Melina J., Petroni, A., Tijet, Nathalie, Lucero, C., Lastovetska, O., Melano, Roberto, Albornoz, E., Corso, Alejandra, Rapoport, M., Melano, R. G., O. Lastovetska, Corso, A., Gomez, Sonia A., Gómez, Sonia Alejandra, Faccone, D., Pasteran, Fernando   +41 more
core   +1 more source

Nacubactam Enhances Meropenem Activity against Carbapenem-Resistant Klebsiella pneumoniae Producing KPC

Antimicrobial Agents and Chemotherapy, 2019
Carbapenem-resistant Enterobacteriaceae (CRE) are resistant to most antibiotics, making CRE infections extremely difficult to treat with available agents. Klebsiella pneumoniae carbapenemases (KPC-2 and KPC-3) are predominant carbapenemases in CRE in the
M. D. Barnes, M. Taracila, Caryn E. Good, S. Bajaksouzian, Laura J. Rojas, D. van Duin, B. Kreiswirth, M. Jacobs, A. Haldimann, K. Papp-Wallace, R. Bonomo   +10 more
semanticscholar   +1 more source

Multiplex visual nucleic acid detection via isothermal cascaded transcription of fluorescent RNA aptamers

VIEW, Volume 7, Issue 3, June 2026.
(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang, Na Luo, Binbin Xie, Jie Luo, Yaling Yuan, Junjie Fan, Zhiyong Liu, Haiyan Gao, Ming Chen, Kai Chang   +9 more
wiley   +1 more source

Modeling meropenem treatment, alone and in combination with daptomycin, for KPC-producing Klebsiella pneumoniae strains with unusually low carbapenem MICs

, 2016
Klebsiella pneumoniae strains producing K. pneumoniae carbapenemase (KPC) cause serious infections in debilitated and immunocompromised patients and are associated with prolonged hospital stays and increased mortality rates.
Rose, null, Gu, null, Gagetti, null, Rosato, null, Pasteran, null, Fernandez, null, Martinez, null [0000-0003-3927-8846], Fatouraei, null, Paz, null, Corso, null   +9 more
core   +1 more source

Carbon monoxide and the 3-kpc arm feature [PDF]

Symposium - International Astronomical Union, 1979
First isolated using the 21-cm HI spectral line, the 3-kpc arm exhibits the largest non-circular motion of any large-scale gaseous structure in the Galaxy (see e.g. Rougoor, 1964). Carbon monoxide observations best delineate the 3-kpc arm because the CO features are both narrower in velocity and also less confused with emission from more local gas than
openaire   +1 more source

Assessing genetic diversity and similarity of 435 KPC-carrying plasmids

, 2019
The global spread and diversification of multidrug-resistant Gram-negative (MRGN) bacteria poses major challenges to healthcare. In particular, carbapenem-resistant Klebsiella pneumoniae strains have been frequently identified in infections and hospital ...
Singh, Abhijeet,, Sveriges lantbruksuniversitet., Müller, Bettina,, Brandt, Christian,   +3 more
core   +2 more sources