Results 131 to 140 of about 169,530 (195)

S-nitrosation impairs KLF4 activity and instigates endothelial dysfunction in pulmonary arterial hypertension

Redox Biology, 2019
Krüppel-like factor 4 (KLF4) is a transcription factor with conserved zinc finger domains. As an essential regulator of vascular homeostasis, KLF4 exerts a protective effect in endothelial cells (ECs), including regulating vasodilation, inflammation ...
Yiqian Ban, Yahan Liu, Yazi Li, Yuying Zhang, Lei Xiao, Yue Gu, Shaoliang Chen, Beilei Zhao, Chang Chen, Nanping Wang   +9 more
doaj   +1 more source

The how and why of lncRNA function: An innate immune perspective. [PDF]

, 2020
Next-generation sequencing has provided a more complete picture of the composition of the human transcriptome indicating that much of the "blueprint" is a vastness of poorly understood non-protein-coding transcripts.
Carpenter, Susan, Covarrubias, Sergio, Robinson, Elektra K   +2 more
core  

C/EBP Homologous Protein (CHOP) Activates Macrophages and Promotes Liver Fibrosis in Schistosoma japonicum-Infected Mice

Journal of Immunology Research, 2019
CCAAT/enhancer-binding homologous protein (CHOP), a transcriptional regulator induced by endoplasmic reticulum stress (ER stress) is a pivotal factor in the ER stress-mediated apoptosis pathway.
Mengyun Duan, Yuan Yang, Shuang Peng, Xiaoqin Liu, Jixin Zhong, Yurong Guo, Min Lu, Hao Nie, Boxu Ren, Xiangzhi Zhang, Lian Liu   +10 more
doaj   +1 more source

Hydroa Vacciniforme Lymphoproliferative Disorder With a Truncating KLF2 Variant Presenting as Benign Photodermatoses

Photodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 3, May 2026.
John Warner‐Levy, Angelia Ong, Nina Farquharson, Jean Ayer   +3 more
wiley   +1 more source

Overexpression of DNA demethylase ten-eleven translocation 3 mediates high expression of Krüppel-like factor 4 in the skin lesions of patients with psoriasis vulgaris

陆军军医大学学报
Objective To investigate the molecular mechanism of DNA methylation of the abnormally high expression of Krüppel-like factor 4 (KLF4) in psoriasis vulgaris lesions.
ZHANG Shuai, LUO Wen, ZHANG Lian
doaj   +1 more source

Defining T Cell Tissue Residency in Humans: Implications for HIV Pathogenesis and Vaccine Design. [PDF]

, 2020
Purpose of review:This review summarizes recent literature defining tissue-resident memory T cells (TRM) and discusses implications for HIV pathogenesis, vaccines, and eradication efforts.Recent findings:Investigations using animal models and human ...
Ferre, April L, Kiniry, Brenna E, Shacklett, Barbara L   +2 more
core  

Luteinizing Hormone Surge-Induced Krüppel-like Factor 4 Inhibits Cyp17A1 Expression in Preovulatory Granulosa Cells. [PDF]

Biomedicines, 2023
Choi Y, Lee O, Ryu K, Roh J.
europepmc   +1 more source

Krüppel-like factor 4 (KLF4): What we currently know.

Gene, 2017
A. Ghaleb, V. Yang
semanticscholar   +1 more source

4,4'-Methylene diphenyl diisocyanate exposure induces expression of alternatively activated macrophage-associated markers and chemokines partially through Krüppel-like factor 4 mediated signaling in macrophages. [PDF]

Xenobiotica, 2023
Lin CC, Law BF, Hettick JM.
europepmc   +1 more source

Defective lipid metabolism associated with mutation in klf-2 and klf-3: important roles of essential dietary salts in fat storage [PDF]

, 2017
Christopher Brey, Farah Lateef, Futwan Al-Mohanna, Jun Ling, Kai Rau, Kavita Thiruchelvam, Kristopher Fernandes, Kshitij Chandel, Megan Schilling, Randy Gaugler, Ranjit Parhar, Sarwar Hashmi, Yi Wang, Zenaida P. Lopez-Dee   +13 more
core   +1 more source