Results 121 to 130 of about 169,530 (195)
Aging in females reduces the number of implantation sites and leads to specific, compartment‐dependent changes in components of the chromosomal passenger complex (pIncenp, Aurora B, Survivin, Borealin) during mouse uterine implantation and decidualization.
Ezgi Golal, Cemre Nur Balci, Nuray Acar
wiley +1 more source
Beyond the chaos: How architecture structures tumour biology
Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner +3 more
wiley +1 more source
Krüppel-like factor 4 (KLF4) is a pluripotency transcription factor that helps in generating induced pluripotent stem cells (iPSCs). We sequenced for the first time the full coding sequence of Camelus dromedarius KLF4 (cKLF4), which is also known as the ...
Abdullah O. Alawad +10 more
doaj +1 more source
The Role of sptf-3 in C. elegans Growth and Development [PDF]
The Sp family of transcription factors has important functions during development in animals. In the nematode Caenorhabditis elegans there are three Sp-related transcription factors (Sptf) which perform similarly important roles in development.
Ulm, Elizabeth
core
Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes [PDF]
Insect nephrocytes are highly endocytic scavenger cells that represent the only invertebrate model for the study of human kidney podocytes. Despite their importance, nephrocyte development is largely uncharacterised.
A Halme +53 more
core +3 more sources
Systematic characterization of the zinc-finger-containing proteins in the mouse transcriptome [PDF]
Zinc-finger-containing proteins can be classified into evolutionary and functionally divergent protein families that share one or more domains in which a zinc ion is tetrahedrally coordinated by cysteines and histidines.
Ravasi, Timothy +8 more
core +1 more source
Combined Chondroitinase and KLF7 Expression Reduce Net Retraction of Sensory and CST Axons from Sites of Spinal Injury [PDF]
Axon regeneration in the central nervous system is limited both by inhibitory extracellular cues and by an intrinsically low capacity for axon growth in some CNS populations.
Blackmore, Murray G. +4 more
core +1 more source
Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation. [PDF]
Inflammatory critical illness is a syndrome that is characterized by acute inflammation and organ injury, and it is triggered by infections and noninfectious tissue injury, both of which activate innate immune receptors and pathways.
Farrar, Katherine +9 more
core +1 more source
Krüppel-like factor 4 acts as an oncogene in colon cancer stem cell-enriched spheroid cells.
Cancer stem cells (CSCs), a rare population in any type of cancers, including colon cancer, are tumorigenic. It has been thought that CSCs are responsible for cancer recurrence, metastasis, and drug resistance.
Zhengwei Leng +8 more
doaj +1 more source
Mir-10b has been reported as a key regulator of metastasis in many human tumours. Moreover, it has also been regarded as a prognostic marker and therapeutic target of colorectal cancer (CRC).
Yue Xie +8 more
doaj +1 more source

