Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies
MedComm, Volume 7, Issue 2, February 2026.The interaction between cancer cells and peripheral nerves: (1) tumor cells could induce the growth of new neural axons and constructing a neural fiber network within the tumor tissue through secreting nerve growth factors; (2) nerve‐derived bioactive molecules can induce perineural invasion of tumor and regulate the malignant phenotype of tumor, such ...
Yan Fu +6 more
wiley +1 more source
Modeling of gap gene expression in Drosophila Kruppel mutants.
PLoS Computational Biology, 2012 The segmentation gene network in Drosophila embryo solves the fundamental problem of embryonic patterning: how to establish a periodic pattern of gene expression, which determines both the positions and the identities of body segments.
Konstantin Kozlov +4 more
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Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory
Immunology, Volume 177, Issue 2, Page 254-269, February 2026.We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco +24 more
wiley +1 more source
Krüppel-Like Factors in Metabolic Homeostasis and Cardiometabolic Disease
Frontiers in Cardiovascular Medicine, 2018 Members of the Krüppel-like factor (KLF) family of transcription factors, which are characterized by the presence of three conserved Cys2/His2 zinc-fingers in their C-terminal domains, control a wide variety of biological processes. In particular, recent
Yumiko Oishi, Ichiro Manabe
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Krüppel-like Factor 15 Suppresses Ferroptosis by Activating an NRF2/GPX4 Signal to Protect against Folic Acid-Induced Acute Kidney Injury [PDF]
, 2023 Xue Yang +9 more
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Selective Interactions of Krüppel-like Factor 9/Basic Transcription Element-binding Protein with Progesterone Receptor Isoforms A and B Determine Transcriptional Activity of Progesterone-responsive Genes in Endometrial Epithelial Cells [PDF]
, 2003 Xuelian Zhang +5 more
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Supplementary Figure Legends 1-9, Tables 1-2 from Identification of Small-Molecule Inhibitors of the Colorectal Cancer Oncogene Krüppel-like Factor 5 Expression by Ultrahigh-Throughput Screening [PDF]
, 2023 Agnieszka B. Bialkowska +12 more
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Krüppel-like factor 1 (KLF1) promoted the proliferation, migration and invasion of human lens epithelial cells by enhancing the expression of Zinc Finger and BTB Domain Containing 7A (ZBTB7A) and activating Wnt/β-catenin pathway [PDF]
, 2021 Guangming Shi, Feng Yang
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Characterization of the prognostic values and response to immunotherapy/chemotherapy of Krüppel‐like factors in prostate cancer [PDF]
, 2020 Jialin Meng +7 more
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Krüppel-like factors in cancer progression: three fingers on the steering wheel [PDF]
, 2013 Ridha Limame +4 more
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