Results 31 to 40 of about 38,499 (231)
Acta Medica, 2009 Practically all mammalian cells including human can switch, according to micro- or macroenvironmental conditions, from states of cellular quiescence to inflammatory activation and vice versa.
Pavel Kuneš +2 more
doaj +1 more source
The gap gene Krüppel of Rhodnius prolixus is required for segmentation and for repression of the homeotic gene sex comb-reduced [PDF]
, 2014 The establishment of the anterior–posterior segmentation in insects requires the concerted action of a hierarchical gene network. Here, we study the orthologue of Krüppel gap gene in the hemipteran Rhodnius prolixus (Rp-Kr).
Lavore, Andrés +3 more
core +2 more sources
The functions and prognostic value of Krüppel‐like factors in breast cancer
Cancer Cell International, 2022 Background Krüppel‐like factors (KLFs) are zinc finger proteins which participate in transcriptional gene regulation. Although increasing evidence indicate that KLFs are involved in carcinogenesis and progression, its clinical significance and biological
Ke-Yun Zhu +7 more
doaj +1 more source
Untersuchungen zur Rolle des Transkriptionsfaktors "Krueppel-like factor 4" in der Sertoli-Zelle der Maus [PDF]
, 2006 Der Zinkfinger-Transkriptionsfaktor "Krueppel-like factor 4" (Klf4) wird in Epithelzellen vieler Gewebe, wie z.B. des Darms, des Magens und der Haut stark exprimiert.
Godmann, Maren +1 more
core +1 more source
Mid-embryo patterning and precision in Drosophila segmentation: Krüppel dual regulation of hunchback. [PDF]
PLoS ONE, 2015 In early development, genes are expressed in spatial patterns which later define cellular identities and tissue locations. The mechanisms of such pattern formation have been studied extensively in early Drosophila (fruit fly) embryos.
David M Holloway, Alexander V Spirov
doaj +1 more source
PACAP neuropeptide promotes Hepatocellular Protection via CREB-KLF4 dependent autophagy in mouse liver Ischemia Reperfusion Injury. [PDF]
, 2020 Organ ischemia reperfusion injury (IRI), associated with acute hepatocyte death, remains an unresolved problem in clinical orthotopic liver transplantation (OLT).
Busuttil, Ronald W +9 more
core
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Proper function of endothelial cells is critical for vascular integrity and organismal survival. Studies over the past 2 decades have identified 2 members of the KLF (Krüppel‐like factor) family of proteins, KLF2 and KLF4, as nodal regulators ...
David R. Sweet +9 more
doaj +1 more source
Effect of Rosuvastatin on Acute Kidney Injury in Sepsis-Associated Acute Respiratory Distress Syndrome. [PDF]
, 2018 Background:Acute kidney injury (AKI) commonly occurs in patients with sepsis and acute respiratory distress syndrome (ARDS). Objective:To investigate whether statin treatment is protective against AKI in sepsis-associated ARDS.
Hsu, Raymond K +5 more
core +3 more sources
The Involvement of Krüppel-like Factors in Cardiovascular Diseases
Life, 2023 Krüppel-like factors (KLFs) are a set of DNA-binding proteins belonging to a family of zinc-finger transcription factors, which have been associated with many biological processes related to the activation or repression of genes, inducing cell growth ...
Michelle G. Santoyo-Suarez +10 more
doaj +1 more source
PLoS ONE, 2014 The role of different lineage specific transcription factors in directing hematopoietic cell fate towards myeloid lineage is well established but the status of epigenetic modifications has not been defined during this important developmental process.
Manjula Karpurapu +9 more
doaj +1 more source