Importance of juvenile hormone signaling arises with competence of insect larvae to metamorphose [PDF]
, 2014 Juvenile hormone (JH) postpones metamorphosis of insect larvae until they have attained an appropriate stage and size. Then, during the final larval instar, a drop in JH secretion permits a metamorphic molt that transforms larvae to adults either ...
Daimon, Takaaki +5 more
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Krüppel -Like Factor 8 is a Stress-Responsive Transcription Factor that Regulates Expression of HuR
Cellular Physiology and Biochemistry, 2014 Background/Aims: HuR is an RNA-binding protein that regulates the post-transcriptional life of thousands of cellular mRNAs and promotes cell survival. HuR is expressed as two mRNA transcripts that are differentially regulated by cell stress.
Suman Govindaraju, Beth S. Lee
doaj +1 more source
Integrative Zoology, EarlyView.Symbiotic gill and nonsymbiotic mantle of mussel Gigantidas haimaensis responded differently to deep‐sea sampling stress caused by acute environmental changes. Sharply increased transcription factors potentially play key roles in initiating the response of sampled deep‐sea macrobenthos to the sampling stress.
Guoyong YAN +4 more
wiley +1 more source
Differential expression of Krüppel-like factor 4 and 5 in oral carcinomas and involvement in the epithelial-mesenchymal transition [PDF]
, 2014 日本歯科大学201
柴田 征紀
core
The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF target genes and is required for proper erythroid maturation in vivo [PDF]
, 2012 The CACCC-box binding protein erythroid Kruppel-like factor (EKLF/KLF1) is a master regulator that directs the expression of many important erythroid genes.
Borg J +22 more
core +1 more source
Cancer Science, Volume 116, Issue 5, Page 1339-1351, May 2025.Single‐nucleus RNA‐seq identified KLF5 as an upregulated gene in SCC‐MT cells. Spatial transcriptomics showed inhibited EMT in SCC‐MT cells. KLF5 downregulation reduced SCC‐MT cell proliferation and increased apoptosis. ABSTRACT Squamous cell carcinoma arising from mature teratoma (SCC‐MT) is a rare ovarian malignancy.
Kosuke Yoshida +13 more
wiley +1 more source
Lactate and Lactylation in AKI‐to‐CKD: Epigenetic Regulation and Therapeutic Opportunities
Cell Proliferation, EarlyView.ABSTRACT Lactate is not only a byproduct of glycolysis, but is also considered an energy source, gluconeogenic precursor, signalling molecule and protein modifier during the process of cellular metabolism. The discovery of lactylation reveals the multifaceted functions of lactate in cellular metabolism and opens new avenues for lactate‐related research.
Yi Hou +7 more
wiley +1 more source
Krüppel homolog 1, an early juvenile hormone-response gene downstream of Methoprene-tolerant, mediates its anti-metamorphic action in the red flour beetle Tribolium castaneum [PDF]
, 2009 Juvenile hormone (JH) prevents ecdysone-induced metamorphosis in insects. However, our knowledge of the molecular mechanisms of JH action is still fragmented.
Minakuchi, Chieka +2 more
core +1 more source
Molecular mechanism for transcriptional regulation of the parathyroid hormone gene by Epiprofin
The FEBS Journal, EarlyView.The secretion of parathyroid hormone (PTH) from the chief cells in the parathyroid glands is regulated by the concentration of extracellular calcium. Epiprofin (Epfn) expression is induced by NFATc2 in response to elevated serum calcium, and Epfn negatively regulates PTH production.
Takashi Nakamura +8 more
wiley +1 more source
Identifizierung potentieller Zielgene des Transkriptionsfaktors Sp3 in vitro und in vivo [PDF]
, 2004 Der ubiquitär vorkommende Transkriptionsfaktor Sp3 (Specificity protein) sowie Sp1, Sp2 und Sp4 gehören zu einer Protein-Familie, die an Sequenzen auf der DNA wie die GC-Box oder die GT-Box binden.
Schmidt, Gabriele +1 more
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