Results 101 to 110 of about 205,719 (255)
Advanced Science, EarlyView.In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li +15 more
wiley +1 more source
Advanced Science, EarlyView.Hybrid FRET–BRET biosensors were developed to monitor RAF–KRAS interactions in living cells. These sensors enable real‐time visualization of interaction dynamics, quantitative spectral analysis, and validation of mutation‐selective inhibitors, providing a versatile platform for probing KRAS regulation and therapeutic responses. ABSTRACT The RAS–RAF–MEK–
Jeong‐Min Go +12 more
wiley +1 more source
Razumevanje okoljskih problemov na dinarskem krasu
Dela, 2003 Na glavnih območjih dinarskega krasa, na Krasu, jadranskih otokih in nizkih ravnikih ob dalmatinski obali prevladujeta tipično sredozemska raba tal, ki povzroča tudi spreminjanje površja, npr.
Jean Nicod
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Advanced Science, EarlyView.Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang +14 more
wiley +1 more source
Cancer Management and Research, 2021 Shaohua Guo,1,2,* Yumeng Ye,3,* Xinyi Liu,4 Yuan Gong,5 Mingyan Xu,4 Lele Song,4,6 Hongyi Liu1 1Department of General Surgery, The First Medical Center of the Chinese PLA General Hospital, Beijing, People’s Republic of China; 2Department of ...
Guo S +6 more
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Brezstropa jama v Podbojevem lazu, Rakov Škocjan
Dela, 2009 Predstavljena je brezstropa jama v Podbojevem lazu, v severozahodnem delu Rakovega Škocjana. Opisane so morfometrične in morfogenetske značilnosti več odsekov brezstrope jame in njene okolice.
Uroš Stepišnik +5 more
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His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models
Advanced Science, EarlyView.His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li +13 more
wiley +1 more source
Tendence spreminjanja podnebja po 2. svetovni vojni na jugovzhodu Krasa
Dela, 2014 Prispevek obravnava trende spreminjanja temperature zraka in padavin v višjem, jugovzhodnem delu Krasa. Zaledno zmerno sredozemsko podnebje se tu prepleta s celinskim podnebjem, zato se značilnosti spreminjanja podnebja nekoliko razlikujejo od trendov ob
Darko Ogrin
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Advanced Science, EarlyView.The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen +15 more
wiley +1 more source
Transcriptome Signature of Immune Cells Post Reovirus Treatment in KRAS Mutated Colorectal Cancer
Cancer Management and Research, 2021 Elisha J Fogel,1 Avishai Samouha,1 Sanjay Goel,2 Radhashree Maitra1,2 1Department of Biology, Yeshiva University, New York, NY, 10033, USA; 2Albert Einstein College of Medicine at Montefiore Medical Center, Bronx, NY, 10461, USACorrespondence: Radhashree
Fogel EJ, Samouha A, Goel S, Maitra R
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