Results 141 to 150 of about 116,020 (268)

Dynamic Prognostic Nutritional Index With Circulating Tumor DNA Predicts Survival in Localized Pancreatic Ductal Adenocarcinoma

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives To evaluate the prognostic significance of baseline and longitudinal changes in prognostic nutritional index (PNI) in localized pancreatic ductal adenocarcinoma (PDAC) and to assess the complementary prognostic value of PNI with tumor burden measured by circulating tumor DNA (ctDNA).
Alex Horowitz, Claire Shen, Dominic J. Vitello, Madison Cox, Amy Wells, Krishay Sridalla, David J. Bentrem, Qiang Zhang, Ishan Roy, Akhil Chawla   +9 more
wiley   +1 more source

Fibroblast-mediated KRAS activation in double-negative prostate cancer. [PDF]

Cell Death Dis
Kamijima T, Izumi K, Hiratsuka K, Inaba T, Koketsu Y, Nakagawa R, Toriumi R, Aoyama S, Kano H, Makino T, Naito R, Kadomoto S, Iwamoto H, Yaegashi H, Kawaguchi S, Nohara T, Shigehara K, Nakata H, Saito Y, Nakagawa-Goto K, Lin WJ, Mizokami A.   +21 more
europepmc   +1 more source

Systematic Review and Meta‐Analysis of Resection Sequence in Synchronous Colorectal Liver Metastasis: Primary vs. Liver First

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background This present systematic review and meta‐analysis aims to compare overall survival (OS), disease‐free survival (DFS), morbidity and mortality outcomes in patients undergoing colorectal first (CRf) versus liver first (Lf) resections with synchronous colorectal liver metastases.
Sofoklis Mavrantonis, Omar Abou El‐Wafa, Sascha Vaghiri, Dimitrios Prassas   +3 more
wiley   +1 more source

Targeting GSTZ1 Sensitizes KRASG12C-Mutant Lung Cancer Cells by Overcoming Glutathione and Glycolysis Pathway Rewiring. [PDF]

Cancer Res Commun
Liao Y, Li X, Liu M, Fernandes VC, Duckett D, Haura EB, Monastyrskyi A, Rix U.   +7 more
europepmc   +1 more source

Nevus Sebaceus: A Cross‐Specialty Survey of Clinical Management in Ireland

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Nevus sebaceus (NS) is a congenital benign hamartomatous malformation typically appearing on the scalp and face as a yellow/orange hairless plaque. Benign secondary tumours can develop but malignant transformation is exceptionally rare.
B. Nolan, M. Murphy, C. O'Connor
wiley   +1 more source

KRAS and BRAF mutations modify adjuvant chemotherapy outcomes in early stage colorectal cancer. [PDF]

NPJ Precis Oncol
Wankhede D, Rodriguez MJU, Edelmann D, Kloor M, Bläker H, Brobeil A, Roth W, Brenner H, Hoffmeister M.   +8 more
europepmc   +1 more source

KRAS mutation subtypes refine prognostic stratification in colorectal cancer: a retrospective cohort study. [PDF]

J Gastrointest Oncol
Li X, Yang ZY, Xu N, Yang J.
europepmc   +1 more source

Exome Sequencing Identifies Variants in MLH1 and ERBB2 as Potential Cancer‐Predisposing Factors in Familial Early‐Onset Colorectal Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Colorectal cancer (CRC) has raised considerable health concerns worldwide, with increasing incidence rates, specifically among younger populations. Despite remarkable progress in diagnosing and treating various diseases, the genetic basis of CRC remains only partially understood.
Behnaz Bagheri, Neda Mohsen‐Pour, Najmeh Salehi, Pardis Ketabi Moghadam, Adel Zeinalpour, Amir Sadeghi, Samira Kalayinia, Nayeralsadat Fatemi   +7 more
wiley   +1 more source

Emerging precision therapeutics for pancreatic ductal adenocarcinoma: KRAS and beyond. [PDF]

Ther Adv Med Oncol
Misirian A, Pai J, Hanna DL.
europepmc   +1 more source

Temperature and lipid composition differentially regulate KRAS assemblies on membranes.

Chem Commun (Camb)
Kang J, Scott E, Yun SD, James VK, Chang JY, Bahramimoghaddam H, Downing J, Evans K, Russell DH, Laganowsky A.   +9 more
europepmc   +1 more source