Results 111 to 120 of about 4,169 (220)

Model‐Informed Optimal Dosing of Anti‐CD47 Antibody Using Target‐Mediated Drug Disposition Model

open access: yesClinical and Translational Science, Volume 18, Issue 8, August 2025.
ABSTRACT IMC‐002, an anti‐cluster of differentiation 47 (CD47) antibody, was developed as a fully human immunoglobulin (Ig) G4 monoclonal antibody targeting CD47. IMC‐002 blocks CD47–signal regulatory protein alpha (SIRPα) interactions, increasing the phagocytosis of cancer cells by macrophages. This study established a target‐mediated drug disposition
Seongmee Jeong   +6 more
wiley   +1 more source

Prioritization approach for circuit breakers to equip with condition monitoring devices

open access: yesArchives of Electrical Engineering, 2020
Circuit Breakers (CBs) play an important role in ensuring the safe operation of protection systems. Condition Monitoring (CM) devices are widely implemented to extend lifetime, and to improve the maintenance quality.
Ali Karimabadi   +2 more
doaj   +1 more source

Dissipation of magnetic fields in star-forming clouds with different metallicities

open access: yes, 2014
We study dissipation process of magnetic fields in the metallicity range $0-1 Z_{\odot}$ for contracting prestellar cloud cores. By solving non-equilibrium chemistry for important charged species including charged grains, we evaluate the drift velocity ...
Doi, Kentaro   +2 more
core   +1 more source

RETROSPECTIVE DIAGNOSIS OF PRIMARY IMMUNODEFICIENCIES FOR CHILDREN IN SVERDLOVSK REGION

open access: yesМедицинская иммунология, 2016
In order to justify a need for mass screening of primary immunodeficiencies (PID) in a regional program for the newborns, we performed a retrospective study of blood spots (archived screening cards) from the babies who deceased at the first year of life (
S. S. Deryabina   +4 more
doaj   +1 more source

Integrating fall‐planted cereal cover crops with herbicides for weed control in dry edible beans

open access: yesAgronomy Journal, Volume 117, Issue 4, July/August 2025.
Abstract Field experiments were conducted in Parma and Kimberly, ID, in 2023 and 2024 to determine weed suppression by fall‐planted small grain cover crops in dry beans (Phaseolus vulgaris L.). Cover crops included barley (Hordeum vulgare L.), triticale (Triticosecale wittmack L.), and winter wheat (Triticum aestivum L.), and these treatments were ...
P. Bhattarai   +3 more
wiley   +1 more source

Analysis of the TREC and KREC Levels in the Dried Blood Spots of Healthy Newborns with Different Gestational Ages and Weights [PDF]

open access: hybrid, 2022
D. A. Cheremokhin   +5 more
openalex   +1 more source

Excited‐state proton transfer of weak and medium‐strength photoacids in confined methanol‐in‐oil reverse micelles

open access: yesBulletin of the Korean Chemical Society, Volume 46, Issue 7, Page 658-665, July 2025.
Excited‐state proton transfer dynamics of weak and medium‐strength photoacids in reverse micelles with water and methanol cores exhibit strong micelle‐size dependences. In small micelles, proton transfer rates (~109 s−1) of these photoacids display minimal dependence on solvent acidity, indicating that restricted solvation dynamics within the confined ...
Taehyung Jang, Yoonsoo Pang
wiley   +1 more source

CLINICAL AND EPIDEMIOLOGICAL ASPECTS OF PRIMARY IMMUNODEFICIENCY DISEASES (PID) AND EARLY DIAGNOSIS OPTIONS

open access: yesМедицинская иммунология, 2017
Neonatal screening for primary immunodeficiencies (PID) provides a unique opportunity for early detection of moderate to severe immune disorders. Thus, the patients could be provided with best available therapy, due to effective treatment according to ...
I. A. Korsunskiy   +5 more
doaj   +1 more source

Role of Newborn Screening for Immunodeficiency in Assessing the Health Status of Children (Review)

open access: yesЖурнал медико-биологических исследований
The early period of the development of the human body, characterized by a rapid growth of organs and tissues, plays an extremely important role in health.
Gyuzyal Sh. Gafiyatullina   +3 more
doaj   +1 more source

Development of a Multiplex Real-Time PCR Assay for the Newborn Screening of SCID, SMA, and XLA

open access: yesInternational Journal of Neonatal Screening, 2019
Numerous studies have shown evidence supporting the benefits of universal newborn screening for primary immunodeficiencies (PID) and for Spinal Muscular Atrophy (SMA).
Cristina Gutierrez-Mateo   +12 more
doaj   +1 more source

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