Real-Life Effectiveness After Switching to Avalglucosidase Alfa in Late-Onset Pompe Disease Patients Worsening on Alglucosidase Alfa Therapy: A French Cohort Study. [PDF]
Illustrating motor function changes before the switch, during the first year, and during the second year after switching treatment. ABSTRACT Late‐onset Pompe disease (LOPD) is a progressive myopathy. Enzyme replacement therapy is effective, but long‐term outcomes vary.
Tard C +24 more
europepmc +2 more sources
Organ-specific low-dose assessment in pediatric radiotherapy using nanodot OSL and NTCP modeling: Application to medulloblastoma. [PDF]
Abstract Background In pediatric radiotherapy, controlling low‐dose exposure is a major challenge, particularly in the treatment of medulloblastoma, where the long life expectancy of young patients makes optimization of radioprotection crucial. Purpose This study provides a comprehensive and quantitative assessment of low‐dose exposure to normal ...
Tantaoui M +6 more
europepmc +2 more sources
Worsening versus advanced heart failure: Management and challenges. [PDF]
Clinical feature, circulating biomarkers and therapeutic management of patients with WHF versus AdvHF. Abbreviations: AdvHF, advanced heart failure; HF, heart failure; HTx, heart transplant; GDMT, guideline‐directed medical therapy; MCS, mechanical circulatory support; NYHA, New York Heart Association; WHF, worsening heart failure.
Palazzuoli A +15 more
europepmc +2 more sources
Causes of Death and Comorbidities in Adult Patients With Late-Onset Pompe Disease: A French Pompe Registry Retrospective Study. [PDF]
ABSTRACT Background and Objectives Mortality in Late‐Onset Pompe Disease (LOPD) has been associated with the rapid progression of respiratory and motor impairment. However, an in‐depth approach to the exact causes of death in these patients is still lacking.
Chitimus DM +26 more
europepmc +2 more sources
Beam collimation and filtration optimization for a novel orthovoltage radiotherapy system. [PDF]
Abstract Background The inaccessibility of clinical linear accelerators in low‐ and middle‐income countries creates a need for low‐cost alternatives. Kilovoltage (kV) x‐ray tubes have shown promise as a source that could meet this need. However, performing radiotherapy with a kV x‐ray tube has numerous difficulties, including high skin dose, rapid dose
Clements N +4 more
europepmc +2 more sources
A Statistical Characterization of Dynamic Brain Functional Connectivity. [PDF]
To our knowledge, this study represents the first demonstration of non‐stationarity within the empirical probability distribution of functional connectivity, measured by Pearson's correlation of fMRI signals. Our analysis utilized individual voxel signals instead of aggregated signals, providing a precise characterization of the empirical probability ...
Chow WW, Seghouane AK, Seghier ML.
europepmc +2 more sources
Architektur Geschichte der Krim
Überblick über die Architektur Geschichte auf der ...
Mitterrutzner, Verena
core +4 more sources
Inflamasi atau radang merupakan reaksi lokal jaringan terhadap infeksi atau cedera dan melibatkan lebih banyak mediator. Inflamasi memiliki angka kejadian yang cukup tinggi, dimana inflamasi dapat disebabkan oleh trauma fisik, infeksi maupun reaksi ...
Debby Juliadi, Ni Putu Dewi Agustini
doaj +5 more sources
Penelitian ini dilatarbelakangi pemikiran pentingnya pengembangan lembar kerja (LK) alternatif untuk mata kuliah kimia bahan makanan, yaitu pada topik kimia es krim.
Saepudin Rahmatullah, Novi Daniyanti
doaj +1 more source
Uji Akseptabilitas Krim Pelembap
Latar Belakang: Mutu produk kosmetik kini tidak hanya dinilai berdasarkan efektivitasnya, namun juga berdasarkan pada sifat-sifat sensori yang dirasakan saat suatu produk digunakan.
Christina Avanti +2 more
doaj +1 more source

