Results 131 to 140 of about 1,869 (158)

The effect of statins on the risk of bleeding in cerebral cavernous malformations: A systematic review and meta-analysis. [PDF]

Surg Neurol Int
Erel BC, Uslu I, Kara B, Turkmenel MG, Celikkiran ZE, Gultekin E, Gayi S, Kilic DB, Kilic B, Yangi DDD, Yangi K.   +10 more
europepmc   +1 more source

CCM Function in the Heart: Working From Outside-In Rather Than Inside-Out. [PDF]

JACC Basic Transl Sci
Kahn ML.
europepmc   +1 more source

A renaissance of cerebral cavernous malformation proteins in vascular physiology. [PDF]

Nat Cardiovasc Res
Abdelilah-Seyfried S, Jo H.
europepmc   +1 more source

Reporting practices of baseline and surgical variables in spinal cavernous malformation surgery: a systematic review. [PDF]

Neurosurg Rev
Ferreira T, Naraine L, Tan JK, Malik HT, Teo MK.   +4 more
europepmc   +1 more source

Natural history of familial cerebral cavernous malformations: the CCM_Italia cohort study. [PDF]

Front Neurol
Lanfranconi S, Scola E, Novelli D, Poggesi A, Pescini F, Pavanello M, Romano F, D'Alessandris QG, Marani W, Signorelli F, Iaconetta G, Torelli G, Fainardi E, Severino M, Remore LG, Bertani GA, Conte G, Capra V, Vasamì A, Nicolis E, Contino G, Ronchi D, Palmieri MC, Previtali A, Mattogno PP, Sturiale CL, Solarino ME, Caliulo R, Bozzi MT, Fratini F, Zanier ER, Latini R, Meessen JMTA, Locatelli M, and the CCM_Italia investigators.   +34 more
europepmc   +1 more source

TLNRD1 is a CCM complex component and regulates endothelial barrier integrity. [PDF]

J Cell Biol
Ball NJ, Ghimire S, Follain G, Pajari AO, Wurzinger D, Vaitkevičiūtė M, Cowell AR, Berki B, Ivaska J, Paatero I, Goult BT, Jacquemet G.   +11 more
europepmc   +1 more source

Protein kinase Cα regulates the nucleocytoplasmic shuttling of KRIT1 [PDF]

Journal of Cell Science, 2021
ABSTRACT KRIT1 is a scaffolding protein that regulates multiple molecular mechanisms, including cell–cell and cell–matrix adhesion, and redox homeostasis and signaling. However, rather little is known about how KRIT1 is itself regulated.
Elisa De Luca, Andrea Perrelli, Harsha Swamy   +2 more
exaly   +4 more sources

Contribution of protein–protein interactions to the endothelial-barrier-stabilizing function of KRIT1 [PDF]

Journal of Cell Science, 2022
ABSTRACT Krev-interaction trapped protein 1 (KRIT1) is an endothelial scaffold protein that promotes adherens junction (AJ) stability. The precise mechanism by which KRIT1 promotes barrier stabilization is unclear. We tested the ability of a panel of KRIT1 constructs containing mutations that inhibit Rap1 binding, ICAP1α binding, disrupt
Harsha Swamy, Angela J Glading
exaly   +3 more sources

Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22 [PDF]

Oncogene, 1997
Krev-1/rap1A is an evolutionarily conserved Ras-family GTPase whose cellular function remains unclear, but which has been proposed to function as a tumor suppressor gene, and may act as a Ras antagonist. To elucidate Krev-1 activity, we have used LexA-Krev-1 in a two-hybrid screen of a HeLa cell cDNA library.
Ilya Serebriiskii, Joseph R Testa, Erica A Golemis   +2 more
exaly   +3 more sources