Results 51 to 60 of about 1,269 (145)
Proteolytic remodelling of the extracellular matrix by pericytes
The FEBS Journal, Volume 293, Issue 13, Page 3899-3953, July 2026.Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Nd1-L may cooperate with KRIT1 in modulating the expression levels of SOD2.
, 2013 KRIT1-null (Krit1-) and KRIT1-expressing (Krit1+) MEF cells grown under standard conditions were either mock transfected (−) or transfected with Flag-Nd1-L cDNA (+), and cell lysates were analyzed by Western blot. The expression levels of Flag-Nd1-L were
Lorenza Trabalzini (308642) +6 more
core +1 more source
A novel CCM3 mutation associated with cerebral cavernous malformation in a Chinese family
Therapeutic Advances in Neurological Disorders, 2020 Background: Cerebral cavernous malformation (CCM), especially the familial form, is a relatively rare congenital and occult vascular disease of the central nervous system.
Xiao-yu Jiang +6 more
doaj +1 more source
, 2022 Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Pharmacology and Physiology, 2016.Disruption of endothelial cell-cell contact is a key event in many cardiovascular diseases and is a characteristic of pathologically ...
DiStefano, Peter, Glading, Angela J.
core
International Journal of Genomics, Volume 2026, Issue 1, 2026.B‐cell chronic lymphocytic leukemia (B‐CLL) is the most common hematological malignancy in adults. Its clinical course is heterogeneous, ranging from indolent forms with slow progression to aggressive variants refractory to conventional treatment.
Alexandra Chu +4 more
wiley +1 more source
Plasma Proteomic Profiling of a Group of Anxious Dogs by LC‐MS/MS: A Case–Control Study
PROTEOMICS – Clinical Applications, Volume 19, Issue 4, July 2025.ABSTRACT Purpose Anxiety is the most common underlying cause of behavioral problems in dogs, which remain a top reason for relinquishment and euthanasia. Despite its high prevalence, anxiety is often underdiagnosed, partly due to a limited understanding of biological processes and absence of diagnostic biomarkers.
Claudia Gaither +4 more
wiley +1 more source
PLoS ONE, 2010 Cerebral cavernous malformations (CCM) are vascular abnormalities of the central nervous system predisposing blood vessels to leakage, leading to hemorrhagic stroke. Three genes, Krit1 (CCM1), OSM (CCM2), and PDCD10 (CCM3) are involved in CCM development.
Christopher F Dibble +8 more
doaj +1 more source
Recent Cutting‐Edge Technologies for the Delivery of Peptide Nucleic Acid
Chemistry – A European Journal, Volume 31, Issue 34, June 17, 2025.This review provides an overview of PNA cellular delivery methods, starting with traditional peptide‐based systems and progressing to advanced approaches using nanoparticles, liposomes, and calixarene. It highlights how these innovative strategies have opened the way for more effective and efficient PNA delivery, ultimately enhancing the potential for ...
Concetta Avitabile +4 more
wiley +1 more source
, 2010 Cerebral cavernous malformations (CCMs) are congenital vascular anomalies of the central nervous system that can result in seizures, haemorrhage, recurrent headaches and focal neurologic deficit.
Patrosso M. C. +7 more
core +2 more sources
Compound Heterozygous Loss‐of‐Function Variants in CCM2L in a Fetus With Tetralogy of Fallot
Molecular Genetics &Genomic Medicine, Volume 13, Issue 6, June 2025.A potential association of CCM2L loss‐of ‐function variants with developmental anomalies of the heart. ABSTRACT Background Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. However, our current understanding of the genetic etiology for TOF is limited.
Dandan Ling +5 more
wiley +1 more source