Serine phosphorylation of the small phosphoprotein ICAP1 inhibits its nuclear accumulation [PDF]
, 2021 Cerebral cavernous malformations (CCMs) are neurovascular abnormalities characterized by thin, leaky blood vessels resulting in lesions that predispose to hemorrhages, stroke, epilepsy, and focal neurological deficits.
Su, Valerie L
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Functional characterisation of a novel nucleoporin gene NUP98 in zebrafish embryo. [PDF]
, 2010 Oral PresentationINTRODUCTION: The nucleoporin gene nup98 is important for the regulation of cytoplasmic-nuclear trafficking. Frequent disruptions of NUP98 during chromosomal translocation in acute myeloid leukaemia suggest that it may play a role in ...
Fung, TK, Leung, AYH, Liang, RHS
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Circulating biomarkers in familial cerebral cavernous malformationResearch in context
EBioMedicineSummary: Background: Cerebral Cavernous Malformation (CCM) is a rare cerebrovascular disease, characterized by the presence of multiple vascular malformations that may result in intracerebral hemorrhages (ICHs), seizure(s), or focal neurological ...
Francesca Lazzaroni +31 more
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Medicinal plants growing in the Judea region: network approach for searching potential therapeutic targets [PDF]
, 2012 Plants growing in the Judea region are widely used in traditional medicine of the Levant region. Nevertheless, they have not so far been sufficiently analyzed and their medicinal potential has not been evaluated.
Arie Budovsky, Vadim E. Fraifeld
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Riwayat Konsumsi Makanan Penderita Strok Yang Masuk Rumah Sakit [PDF]
, 2014 Stroke is one of main contributing diseases to global death as well as in Indonesia. One of risk factors for stroke is food pattern while the post stroke food pattern affect on later survival.
Budiman, B. (Basuki) +2 more
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Systems biology and proteomic analysis of cerebral cavernous malformation [PDF]
, 2014 Cerebral cavernous malformations (CCM) are vascular anomalies caused by mutations in genes encoding KRIT1, OSM and PDCD10 proteins causing hemorrhagic stroke. We examine proteomic change of loss of CCM gene expression.
Bencharit, Sompop +6 more
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Ras-like small GTPases in platelet biology [PDF]
, 2002 In a human body, the behaviour of each cell is controlled by signals like hormones or growth factors. A cell receives such messages by means of specific receptors. These transmit the messages to other proteins in the cell and so on. Such cascades control
Bruyn, K.M.T. (Kimball Marinus Theodor) de
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Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity [PDF]
, 2010 Endothelial cell–cell junctions regulate vascular permeability, vasculogenesis, and angiogenesis. Familial cerebral cavernous malformations (CCMs) in humans result from mutations of CCM2 (malcavernin, OSM, MGC4607), PDCD10 (CCM3), or KRIT1 (CCM1), a Rap1
Akers +69 more
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Journal of Pain Research, 2019 Weiwei Yu, Haiqiang Jin, Qian You, Ding Nan, Yining HuangDepartment of Neurology, Peking University First Hospital, Beijing 100034, People’s Republic of ChinaAbstract: Cerebral cavernous malformations (CCMs) are one of the most common types of ...
Yu W, Jin H, You Q, Nan D, Huang Y
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The Molecular Pathogenesis Of Cerebral Cavernous Malformations [PDF]
, 2018 Cerebral cavernous malformation (CCM) is a human genetic, cerebrovascular disease that is caused by loss of function mutations in three non-homologous protein coding genes: KRIT1, CCM2, and PDCD10. These proteins form a heterotrimeric CCM adaptor complex
Tang, Alan Tien
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