Results 181 to 190 of about 157,775 (261)

Familial Cerebral Cavernous Malformations: Pathophysiology, Genetics, Biomarkers, and Treatment Perspectives

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
Cerebral cavernous malformations (CCMs) are vascular lesions in the brain caused by inherited genetic mutations in the CCM1/2/3 genes that disrupt normal blood vessel function. This work demonstrates that these mutations lead to endothelial dysfunction, inflammation, and iron accumulation, which can be detected by magnetic resonance imaging (MRI) and ...
Fabrícia Lima Fontes‐Dantas, Gustavo da Fontoura Galvão, Alexandre Martins Cunha, Pedro de Sena Murteira Pinheiro, Verônica Morandi, Jorge Marcondes de Souza   +5 more
wiley   +1 more source

Luteinizing Hormone Surge-Induced Krüppel-like Factor 4 Inhibits Cyp17A1 Expression in Preovulatory Granulosa Cells. [PDF]

Biomedicines, 2023
Choi Y, Lee O, Ryu K, Roh J.
europepmc   +1 more source

How the Fibrotic Lung Microenvironment Regulates Stem Cell Behavior: Immune Cues, Extracellular Matrix Remodeling, and Therapeutic Implications

Analytical Cellular Pathology, Volume 2026, Issue 1, 2026.
Pulmonary fibrosis (PF) is a chronic and progressive interstitial lung disease characterized by excessive extracellular matrix (ECM) deposition and remodeling of lung structures. Currently, no effective clinical treatments exist to reverse or halt the progression of PF.
Zihan Zhou, Shuhua Han, Yuanfang Duan, Minqi Hong, Jie Huang, Andrey Elchaninov   +5 more
wiley   +1 more source

Plasma proteome correlates of lipid and lipoprotein: biomarkers of metabolic diversity and inflammation in children of rural Nepal. [PDF]

, 2019
Proteins involved in lipoprotein metabolism can modulate cardiovascular health. While often measured to assess adult metabolic diseases, little is known about the proteomes of lipoproteins and their relation to metabolic dysregulation and underlying ...
Christian, Parul, Cole, Robert N, Eroglu, Abdulkerim, Groopman, John, Lee, Sun Eun, Schulze, Kerry, Stewart, Christine P, West, Keith P, Wu, Lee S-F, Yager, James D   +9 more
core  

Differential Expression of Human Endogenous Retroviruses‐W in Multiple Sclerosis and Epilepsy: A Comparative Study With Healthy Controls

Advances in Virology, Volume 2026, Issue 1, 2026.
Human endogenous retroviruses (HERVs) are the remnants of viral infections that occurred in our ancestors, subsequently integrated into the human genome. They make up about 8% of the human genome. Increased HERV expression occurs in physiological and pathological conditions, especially neurological diseases.
Sina Mahdavi, Vahdat Poortahmasebi, Daryoush Savadi Oskouei, Arezou Azadi, Sara Mafi, Javid Sadeghi, Hossein Bannazadeh Baghi, Mahin Ahangar Oskouee, Jasbir Arora (RSS)   +8 more
wiley   +1 more source

Mechanism of Non–Small Cell Lung Cancer–Derived Extracellular Vesicle miRNA hsa‐let‐7b‐5p Targeting AP1S1 to Regulate M2 Macrophage Polarization

International Journal of Genomics, Volume 2026, Issue 1, 2026.
Background Non–small cell lung cancer (NSCLC) accounts for over 80% of lung cancer cases. Further, the complex tumor immune microenvironment (TIME) is a critical factor in treatment resistance and poor prognosis associated with tumors. Tumor‐associated macrophages (TAMs), a major component of the TIME, significantly promote tumor progression through ...
Lijuan Liu, Zixing Kou, Tianhua Wang, Qihang Shang, Qinxiang Zhang, Guanghui Liu, Jing Ai, Yanwen Zhao, Changgang Sun, Zhijie Xu   +9 more
wiley   +1 more source

Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival [PDF]

, 2015
C-C Lin, Shalini Sharma, Mark Farrugia, Sarah L. McLaughlin, Ryan J. Ice, Yuriy V. Loskutov, Elena N. Pugacheva, Kathleen M. Brundage, D Chen, J. Michael Ruppert   +9 more
openalex   +1 more source

Supplementary Figure 1 from Haploinsufficiency of Kruppel-Like Factor 4 Promotes Adenomatous Polyposis Coli–Dependent Intestinal Tumorigenesis

, 2023
Amr M. Ghaleb, Beth B. McConnell, Mandayam O. Nandan, Jonathan P. Katz, Klaus H. Kaestner, Vincent W. Yang   +5 more
openalex   +1 more source

Kruppel-like factor 4 promotes autophagy in human monocytes leukemia cells under high glucose conditions by inhibiting AKT/mTOR signaling pathway [PDF]

, 2022
Rui Zhang, Sisi Chen, Tongdan Wang, Pei Yu   +3 more
openalex   +1 more source

Kruppel-like factor 4 (KLF4) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source