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Tcf7l1 promotes transcription of Kruppel-like factor 4 during Xenopus embryogenesis
Qing Cao +4 more
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Angiotensin II- Angiotensin II Receptor Type 1 Signaling Facilitates Gastric Cancer Metastasis via Kruppel-like Factor 4 Suppression and Tight Junction Breakdown [PDF]
Sooraj Kakkat +13 more
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Role of Kruppel-like factor 4 in atherosclerosis
Clinica Chimica Acta, 2021Atherosclerosis is one of the chronic progressive diseases, which is caused by vascular injury and promoted by the interaction of various inflammatory factors and inflammatory cells. In recent years, kruppel-like factor 4 (KLF4), a significant transcription factor that participated in cell growth, differentiation and proliferation, has been proved to ...
Chen Yang +7 more
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American Journal of Rhinology & Allergy, 2023
Background Allergic rhinitis (AR) is a chronic nasal inflammation, characterized by nasal epithelial dysfunction. Gene therapy targeting transcription factors is a promising strategy for quenching allergic inflammation, including AR. Objective This study
Jiaoli Yao +4 more
semanticscholar +1 more source
Background Allergic rhinitis (AR) is a chronic nasal inflammation, characterized by nasal epithelial dysfunction. Gene therapy targeting transcription factors is a promising strategy for quenching allergic inflammation, including AR. Objective This study
Jiaoli Yao +4 more
semanticscholar +1 more source
Environmental Toxicology, 2023
MoS2 nanosheets (NSs) are novel 2D nanomaterials (NMs) being used in many important fields. Recently, we proposed the need to evaluate the influences of NMs on Kruppel‐like factors (KLFs) even if these materials are relatively biocompatible.
You Xiao +7 more
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MoS2 nanosheets (NSs) are novel 2D nanomaterials (NMs) being used in many important fields. Recently, we proposed the need to evaluate the influences of NMs on Kruppel‐like factors (KLFs) even if these materials are relatively biocompatible.
You Xiao +7 more
semanticscholar +1 more source
Kruppel-like factor 4 regulates keratinocyte senescence
Biochemical and Biophysical Research Communications, 2018Keratinocyte replicative senescence has an important role in time-related changes of epidermis. Previous studies demonstrated that miRNAs play key roles in inhibiting proliferation and in the acquisition of the keratinocyte senescent phenotype as well as in individual ageing.
PANATTA, EMANUELE +11 more
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44 KRUPPEL-LIKE FACTOR 4 REGULATES ENDOTHELIAL INFLAMMATION.
Journal of Investigative Medicine, 2007Background The vascular endothelium plays a critical role in vascular homeostasis. A limited proinflammatory, prothrombotic state is appropriate in the context of infection or wound healing, but sustained endothelial activation leads to deleterious conditions such as atherosclerosis and pathologic thrombosis.
A. Hamik +8 more
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Kruppel-Like Factor 4 represses osteoblast differentiation via ciliary Hedgehog signaling
Experimental Cell Research, 2018Primary cilia are appendages observed in most types of cells, and serve as cellular antennae for sensing environmental signals. Evidence is accumulating that correct ciliogenesis and ciliary functions are indispensable for normal skeletal development by regulating signaling pathways important for bone development.
Yuto, Takeuchi +9 more
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