Results 251 to 260 of about 157,775 (261)

MicroRNA‐10b regulates the renewal of spermatogonial stem cells through Kruppel‐like factor 4

Cell Biochemistry and Function, 2017
MicroRNAs (miRs) are functionally important in spermatogenesis, which is the self‐renewal or differentiation of spermatogonial stem cells (SSCs). Here, we report a novel role for miR‐10b in regulating the self‐renewal of mouse SSCs. We showed that miR‐10b was highly expressed in mouse SSCs in vitro and enhanced SSC proliferation.
Jiang Li, Xiang Liu, Xiaopeng Hu, Geng G. Tian, Wenzhi Ma, Xiuying Pei, Yanrong Wang, Ji Wu   +7 more
openaire   +2 more sources

Roles of Kruppel-like factor 4 in oesophageal epithelial cells in Barrett's epithelium development

Gut, 2010
The mechanism of transformation to intestinal metaplasia in Barrett's oesophagus has not been clarified. We previously reported that bile acids activate the Cdx2 promoter via nuclear factor kappa B (NF-κB) and stimulate production of Cdx2 protein in oesophageal keratinocytes, resulting in production of intestinal-type mucin. Krüppel-like factor 4 (KLF4)
Hideaki, Kazumori, Shunji, Ishihara, Yoshiko, Takahashi, Yuji, Amano, Yoshikazu, Kinoshita   +4 more
openaire   +2 more sources

Krüppel-like factor 4 (KLF4) facilitates lipid production in immortalized human sebocytes via regulating the expression of SREBP1.

Biochemical and Biophysical Research Communications - BBRC, 2023
Xia Li, Xin Zeng, Doyeon Kim, Jian Jiang, Feng juan Wei, Jing-yu Zhang, Bao Chai, Li Fu, Y. Lee, Chang-Hyeon Kim, Hongxiang Chen   +10 more
semanticscholar   +1 more source

Pentadecapeptide BPC 157 efficiently reduces radiation-induced liver injury and lipid accumulation through Kruppel-like factor 4 upregulation both in vivo and in vitro.

Life Science, 2022
Bing-Shen Huang, Shih-Chiang Huang, Fan-Hsin Chen, Y. Chang, Hsiu-Fu Mei, Hsiu-Yun Huang, Wan-Yu Chen, J.-H. Su Pang   +7 more
semanticscholar   +1 more source

[Knockdown of Kruppel like factor 4 (KLF4) promotes RAW264.7 macrophages into M1 polarization].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2020
Objective To investigate the effects of Kruppel like factor 4 (KLF4) gene knockdown on the polarization of RAW264.7 macrophages. Methods KLF4 knockdown lentiviral vector was constructed by RNA interfering. The lentiviral vector was transfected into RAW264.7 cells to realize stable KLF4 gene silencing in RAW264.7 cells.
Liang, Sun, Xin, Li, Wenjie, Ji, Luqing, Wei   +3 more
openaire   +1 more source

Bifunctional Role of Kruppel-Like Factor 4 in Hematological Malignancies

Forum on Immunopathological Diseases and Therapeutics, 2016
Mario Morales-Martinez, Luz A. Franco-Cea, Liliana Moreno Vargas, Otoniel Martinez-Maza, Sara Huerta-Yepez, Mario I. Vega   +5 more
openaire   +1 more source

Kruppel-Like Factor 4: From Physiological Functions to Tumor Therapy

Forum on Immunopathological Diseases and Therapeutics, 2016
Ruocong Zhao, Yunxin Lai, Peng Li
openaire   +1 more source

Kruppel-like factor 4 regulates developmental angiogenesis through disruption of the RBP-J–NICD–MAML complex in intron 3 of Dll4

Angiogenesis, 2019
Evgenii Boriushkin, Hui Zhang, Mitchell Becker, Janet C. Peachey, M. Shatat, R. Adams, A. Hamik   +6 more
semanticscholar   +1 more source

Novel abciximab-Kruppel-like factor 4-plasmid dual-delivery titanium dioxide-coated coronary stent

International Journal of Cardiology, 2013
Jin Sook, Kwon, Sun-Jung, Song, Eun Ju, Yang, Yong Sook, Kim, Kyung Seob, Lim, Dong Gon, Kim, Dong Lyun, Cho, Myung Ho, Jeong, Youngkeun, Ahn   +8 more
openaire   +2 more sources

Role of Immune-Cell-Expressing Kruppel-Like Factor 4 in Cancer Development

Forum on Immunopathological Diseases and Therapeutics, 2016
openaire   +1 more source