Results 121 to 130 of about 24,542 (261)
PLoS Pathogens, 2020 Infection by Kaposi's sarcoma-associated herpesvirus (KSHV) is necessary for the development of Kaposi's sarcoma (KS), which most often develops in HIV-infected individuals. KS frequently has oral manifestations and KSHV DNA can be detected in oral cells.
Marion Gruffaz +10 more
doaj +1 more source
Lack of CD8+ T-cell co-localization with Kaposi’s sarcoma- associated herpesvirus infected cells in Kaposi’s sarcoma tumors [PDF]
, 2020 Despite the close association between Kaposi’s sarcoma (KS) and immune dysfunction, it remains unclear whether tumor infiltrating immune cells (TIIC), by their absence, presence, or dysfunction, are mechanistically correlated with KS pathogenesis ...
Kolape, Jaydeep +7 more
core +1 more source
Targeting the ATP-dependent formation of herpesvirus ribonucleoprotein particle assembly as an antiviral approach [PDF]
, 2016 Human herpesviruses are responsible for a range of debilitating acute and recurrent diseases, including a number of malignancies. Current treatments are limited to targeting the herpesvirus DNA polymerases, however with emerging viral resistance and ...
Foster, R +6 more
core +1 more source
Identification of Target Genes Regulated by KSHV miRNAs in KSHV-Infected Lymphoma Cells
Pathology & Oncology Research, 2015 This study aimed to identify target genes regulated by KSHV miRNAs in KSHV-infected lymphoma cells. Original Ago HITS-CLIP data of BC-3 and BCBL-1 cell lines were downloaded from SRA database in NCBI, including mRNA and miRNA samples. The raw mRNA reads were mapped into human reference genome hg19 via TopHat for read alignment.
Liangliang, Quan +5 more
openaire +2 more sources
Pathology of Kaposi's sarcoma-associated herpesvirus infection
Frontiers in Microbiology, 2011 Kaposi’s sarcoma-associated herpesvirus (KSHV, human herpesvirus 8, HHV-8) is a human herpesvirus, classified as a gamma-herpesvirus. KSHV is detected in Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and some cases of multicentric Castleman’s ...
Hitomi eFukumoto +4 more
doaj +1 more source
mBio, 2017 Kaposi’s sarcoma-associated herpesvirus (KSHV) is associated with the human malignancy Kaposi’s sarcoma and the lymphoproliferative disorders primary effusion lymphoma and multicentric Castleman’s disease. KSHV establishes lytic infection of monocytes in
Kurtis M. Host +7 more
doaj +1 more source
Speculations on the clinical significance of asymptomatic viral infections [PDF]
, 2016 A detailed understanding of asymptomatic chronic viral infections is critical to analyse their pathogenesis, assess the severity and burden of disease and, where required, optimize public health control measures.
Gentile, Giuseppe, Micozzi, Alessandra
core +1 more source
KSHV LANA's expanding bag of tricks
Blood, 2008 In this issue of Blood, Di Bartolo and colleagues report that KSHV targets the TGF-β signaling pathway in latently infected tumor cells.
Andrew J, Barbera, Kenneth M, Kaye
openaire +3 more sources
Journal of VirologyKaposi’s sarcoma-associated herpesvirus (KSHV) is a human gammaherpesvirus associated with Kaposi’s sarcoma and B cell malignancies. Like all herpesviruses, KSHV contains conserved envelope glycoproteins (gps) involved in virus binding, entry, assembly ...
Ryan D. Estep +5 more
doaj +1 more source
Molecular medicine of microRNAs: structure, function and implications for diabetes [PDF]
, 2008 MicroRNAs (miRNAs) are a family of endogenous small noncoding RNA molecules, of 19–28 nucleotides in length. In humans, up to 3% of all genes are estimated to encode these evolutionarily conserved sequences.
Duncan +5 more
core +1 more source