Results 111 to 120 of about 22,605 (225)

Pathology of Kaposi's sarcoma-associated herpesvirus infection

Frontiers in Microbiology, 2011
Kaposi’s sarcoma-associated herpesvirus (KSHV, human herpesvirus 8, HHV-8) is a human herpesvirus, classified as a gamma-herpesvirus. KSHV is detected in Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and some cases of multicentric Castleman’s ...
Hitomi eFukumoto, Hitomi eFukumoto, Takayuki eKanno, Hideki eHasegawa, Harutaka eKatano   +4 more
doaj   +1 more source

Signatures of oral microbiome in HIV-infected individuals with oral Kaposi's sarcoma and cell-associated KSHV DNA.

PLoS Pathogens, 2020
Infection by Kaposi's sarcoma-associated herpesvirus (KSHV) is necessary for the development of Kaposi's sarcoma (KS), which most often develops in HIV-infected individuals. KS frequently has oral manifestations and KSHV DNA can be detected in oral cells.
Marion Gruffaz, Tinghe Zhang, Vickie Marshall, Priscila Gonçalves, Ramya Ramaswami, Nazzarena Labo, Denise Whitby, Thomas S Uldrick, Robert Yarchoan, Yufei Huang, Shou-Jiang Gao   +10 more
doaj   +1 more source

Trends in Kaposi's sarcoma-associated Herpesvirus antibodies prior to the development of HIV-associated Kaposi's sarcoma: a nested case-control study. [PDF]

, 2014
HIV-associated Kaposi's sarcoma (KS) is a public health challenge in sub-Saharan Africa since both the causative agent, Kaposi's sarcoma associated-herpesvirus (KSHV), and the major risk factor, HIV, are prevalent. In a nested case-control study within a
Elliott, Alison M, Johnston, W Thomas, Mayanja, Billy N, Miley, Wendell, Nalwoga, Angela, Newton, Robert, Wakeham, Katie, Webb, Emily L, Whitby, Denise   +8 more
core   +1 more source

Identification of Target Genes Regulated by KSHV miRNAs in KSHV-Infected Lymphoma Cells

Pathology & Oncology Research, 2015
This study aimed to identify target genes regulated by KSHV miRNAs in KSHV-infected lymphoma cells. Original Ago HITS-CLIP data of BC-3 and BCBL-1 cell lines were downloaded from SRA database in NCBI, including mRNA and miRNA samples. The raw mRNA reads were mapped into human reference genome hg19 via TopHat for read alignment.
Liangliang, Quan, Tao, Qiu, Jiulong, Liang, Miao, Li, Yu, Zhang, Kai, Tao   +5 more
openaire   +2 more sources

Generation of chimeric forms of rhesus macaque rhadinovirus expressing KSHV envelope glycoproteins gH and gL for utilization in an NHP model of infection

Journal of Virology
Kaposi’s sarcoma-associated herpesvirus (KSHV) is a human gammaherpesvirus associated with Kaposi’s sarcoma and B cell malignancies. Like all herpesviruses, KSHV contains conserved envelope glycoproteins (gps) involved in virus binding, entry, assembly ...
Ryan D. Estep, Helen Li, Aparna N. Govindan, Kaidlyn A. McDonald, Michael K. Axthelm, Scott W. Wong   +5 more
doaj   +1 more source

Kaposi’s Sarcoma-Associated Herpesvirus Increases PD-L1 and Proinflammatory Cytokine Expression in Human Monocytes

mBio, 2017
Kaposi’s sarcoma-associated herpesvirus (KSHV) is associated with the human malignancy Kaposi’s sarcoma and the lymphoproliferative disorders primary effusion lymphoma and multicentric Castleman’s disease. KSHV establishes lytic infection of monocytes in
Kurtis M. Host, Sarah R. Jacobs, John A. West, Zhigang Zhang, Lindsey M. Costantini, Charles M. Stopford, Dirk P. Dittmer, Blossom Damania   +7 more
doaj   +1 more source

NKG2D and its ligands: one for all, all for one [PDF]

, 2018
The activating receptor NKG2D is peculiar in its capability to bind to numerous and highly diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal cells but can be induced on damaged, transformed or infected cells, with ...
Cerboni, Cristina, Cippitelli, Marco, Fionda, Cinzia, Molfetta, Rosa, Paolini, Rossella, Santoni, Angela, Soriani, Alessandra, Zingoni, Alessandra   +7 more
core   +2 more sources

KSHV LANA's expanding bag of tricks

Blood, 2008
In this issue of Blood, Di Bartolo and colleagues report that KSHV targets the TGF-β signaling pathway in latently infected tumor cells.
Andrew J, Barbera, Kenneth M, Kaye
openaire   +3 more sources

Rational engineering of microRNA-regulated viruses for cancer gene therapy [PDF]

, 2013
MicroRNAs (miRNAs) are small noncoding RNA molecules that have important regulatory roles in a wide range of biological processes. miRNAs are often expressed in a tissue- and/or differentiation state-specific patterns, and it is estimated that miRNAs can
Ylösmäki, Erkko
core  

Multiple human herpesvirus-8 infection [PDF]

, 2003
In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction.
Beyari, MM, Cook, RD, Hodgson, TA, Kondowe, W, Molyneux, EM, Porter, SR, Scully, CM, Teo, CG   +7 more
core   +1 more source