Results 91 to 100 of about 22,605 (225)

Liquid–Liquid Phase Separation in Viral Infection and Immunology

MedComm, Volume 7, Issue 4, April 2026.
LLPS organizes viral replication and antiviral immunity. Viruses hijack LLPS to form replication factories and evade immune sensors, while hosts assemble LLPS‐driven signaling hubs (e.g., MAVS, RIG‐I, and SGs) to amplify interferon responses. Targeting these condensate interfaces offers novel therapeutic strategies against infectious diseases ...
Jiuzhi Xu, Lan Bai, Bin Wang, Hai Song, Long Zhang, Fangfang Zhou   +5 more
wiley   +1 more source

KSHV-Mediated Angiogenesis in Tumor Progression [PDF]

Viruses, 2016
Human herpesvirus 8 (HHV-8), also known as Kaposi’s sarcoma-associated herpesvirus (KSHV), is a malignant human oncovirus belonging to the gamma herpesvirus family. HHV-8 is closely linked to the pathogenesis of Kaposi’s sarcoma (KS) and two other B-cell lymphoproliferative diseases: primary effusion lymphoma (PEL) and a plasmablastic variant of ...
Pravinkumar Purushothaman, Timsy Uppal, Roni Sarkar, Subhash Verma   +3 more
openaire   +4 more sources

Prevalence of Kaposi’s sarcoma-associated herpesvirus in Uygur and Han populations from the Urumqi and Kashgar regions of Xinjiang, China [PDF]

, 2017
Kaposi’s sarcoma-associated herpesvirus (KSHV) is the infectious etiologic agent associated with Kaposi’s sarcoma (KS), primary effusion lymphoma, and multicentric Castleman disease.
Cui, Meng, Han, Li-Li, Liu, Zhen-Qiu, Shu, Zhan-Jun, Wood, Charles, Yang, Yang, Zeng, Yan, Zhang, Tiejun, Zheng, Jun   +8 more
core   +1 more source

An Interaction between KSHV ORF57 and UIF Provides mRNA-Adaptor Redundancy in Herpesvirus Intronless mRNA Export [PDF]

, 2011
The hTREX complex mediates cellular bulk mRNA nuclear export by recruiting the nuclear export factor, TAP, via a direct interaction with the export adaptor, Aly.
Blackbourn, D.J., Boyne, J.R., Hautbergue, G.M., Jackson, B.R., Noerenberg, M., Taylor, A., Walsh, M.J., Wheat, R., Whitehouse, A., Wilson, S.A.   +9 more
core   +4 more sources

Immune non‐response despite effective antiretroviral therapy in people living with HIV: A review of potential mechanisms, biomarkers and therapeutic approaches

HIV Medicine, Volume 27, Issue 4, Page 498-512, April 2026.
Abstract Introduction A proportion of people living with HIV (PLWH) fail to restore their CD4 count or their CD4/CD8 ratio despite effective antiretroviral therapy (ART). PLWH with immune non‐response (INR) are at a higher risk of both AIDS and non‐AIDS events. The underlying mechanisms of INR remain unclear.
Charlotte Silvestre, Antoine Gross, Alain Makinson   +2 more
wiley   +1 more source

Functional dissection of latency-associated nuclear antigen 1 of Kaposi's sarcoma-associated herpesvirus involved in latent DNA replication and transcription of terminal repeats of the viral genome [PDF]

, 2015
Latency-associated nuclear antigen 1 (LANA1) of Kaposi's sarcoma-associated herpesvirus (KSHV) is implicated in the maintenance of the viral genome during latent infection.
Choe, Joonho, Gwack, Yousang, Lee, Daeyoup, Lim, Chunghun, Sohn, Hekwang   +4 more
core   +1 more source

DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS

Neuropathology, Volume 46, Issue 2, April 2026.
ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Maria K. Jauhiainen, Outi I. Mielonen, Aaro Haapaniemi, Maria Söderlund‐Venermo, Jaana Hagström, Maria F. Perdomo, Saku T. Sinkkonen, Antti A. Mäkitie   +7 more
wiley   +1 more source

Molecular Biology of KSHV Lytic Reactivation [PDF]

Viruses, 2015
Kaposi’s sarcoma-associated herpesvirus (KSHV) primarily persists as a latent episome in infected cells. During latent infection, only a limited number of viral genes are expressed that help to maintain the viral episome and prevent lytic reactivation. The latent KSHV genome persists as a highly ordered chromatin structure with bivalent chromatin marks
Pravinkumar Purushothaman, Timsy Uppal, Subhash Verma   +2 more
openaire   +4 more sources

Selective autophagy impedes KSHV entry after recruiting the membrane damage sensor galectin-8 to virus-containing endosomes

Cell Reports
Summary: Kaposi sarcoma-associated herpesvirus (KSHV) is an oncogenic γ-herpesvirus. Autophagy during KSHV entry has remained unexplored. We show that LC3 lipidation as a hallmark of autophagy is induced shortly after KSHV entry.
Katarina Wendy Schmidt, Charlotte Montespan, Danielle Thompson, Miriam S. Lucas, Laure-Anne Ligeon, Harald Wodrich, Alexander S. Hahn, Urs F. Greber, Christian Münz   +8 more
doaj   +1 more source

Utilising proteomic approaches to understand oncogenic human herpesviruses [PDF]

, 2014
The γ‑herpesviruses Epstein-Barr virus and Kaposi's sarcoma‑associated herpesvirus are successful pathogens, each infecting a large proportion of the human population.
Baquero-Perez, B, Berndt, A, Hughes, DJ, Jackson, BR, Owen, CB, Schumann, S, Whitehouse, A   +6 more
core   +1 more source