Results 91 to 100 of about 18,080 (165)

Identification of the Kaposi\u27s Sarcoma-associated Herpesvirus (KSHV) Surface Glycoprotein Targets of Human KSHV-specific Neutralizing Antibody Responses [PDF]

, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), is the etiological agent of Kaposi’s sarcoma (KS), and is also associated with two B cell malignancies, primary effusion lymphoma and multicentric Castleman\u27s ...
Mortazavi, Yasaman
core  

Factors affecting Kaposi’s sarcoma-associated herpesvirus transmission in rural Ugandan households, a longitudinal study

Infectious Agents and Cancer
Background We report the impact of HIV infection within a household on oral Kaposi’s sarcoma-associated herpesvirus (KSHV) shedding. Methods We enrolled 469 individuals from 90 households.
Katherine R. Sabourin, Vickie A. Marshall, Will Eaton, Beatrice Kimono, Joseph Mugisha, Wendell J. Miley, Nazzarena Labo, Gabriela Samayoa-Reyes, Denise Whitby, Rosemary Rochford, Robert Newton   +10 more
doaj   +1 more source

Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas.

PLoS Pathogens, 2012
KSHV is the etiological agent of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and a subset of multicentricCastleman's disease (MCD). The fact that KSHV-encoded miRNAs are readily detectable in all KSHV-associated tumors suggests a potential ...
Irina Haecker, Lauren A Gay, Yajie Yang, Jianhong Hu, Alison M Morse, Lauren M McIntyre, Rolf Renne   +6 more
doaj   +1 more source

KSHV vGPCR: A VIRAL ONCOPROTEIN THAT TRIGGERS AUTOPHAGY AND CELLULAR SENESCENCE

, 2011
Autophagy (literally to ‘self-eat’) is an intracellular, catabolic mechanism to degrade and recycle cytoplasmic contents in response to metabolic, oxidative, and genotoxic stresses.
Cyr, David P
core  

EBV/KSHV co-infection: an effective partnership

, 2018
International audienceKaposi's sarcoma human herpesvirus (KSHV) is the etiologic agent of primary effusion lymphoma (PEL) in which Epstein-Barr virus (EBV) is also very often present. By using a humanized mouse model, Pr.
Henri Gruffat, Manet, Evelyne, Gruffat, Henri, Evelyne Manet   +3 more
core   +1 more source

KSHV: forgotten but not gone

, 2011
Thirty years ago, Kaposi sarcoma (KS) arose as a prominent manifestation of the AIDS epidemic. Seventeen years ago we discovered the virus that causes KS, 1 Kaposi sarcoma-associated herpesvirus (KSHV), and within a year KSHV had been also shown to be ...
Moore, Patrick S., Patrick S. Moore, Yuan Chang, Chang, Yuan   +3 more
core   +1 more source

Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres

, 2021
To achieve replicative immortality, cancer cells must activate telomere maintenance mechanisms to prevent telomere shortening. ~85% of cancers circumvent telomeric attrition by re-expressing telomerase, while the remaining ~15% of cancers induce ...
Niklas Feldhahn (74533), Paulina Marzec (8306877), Päivi M Ojala (10020638), Mark Bower (372162), Paul J Farrell (10020635), Timothy P Lippert (10020629), Aurora I Idilli (10020632), Grzegorz Sarek (251561), Aleksandra Vancevska (7057850), Simon J Boulton (8274444)   +9 more
core  

KSHV-Mediated Angiogenesis in Tumor Progression

, 2016
Human herpesvirus 8 (HHV-8), also known as Kaposi’s sarcoma-associated herpesvirus (KSHV), is a malignant human oncovirus belonging to the gamma herpesvirus family. HHV-8 is closely linked to the pathogenesis of Kaposi’s sarcoma (KS) and two other B-cell
Roni Sarkar, Sarkar, Roni, Subhash Verma, Verma, Subhash C., Subhash C. Verma, Purushothaman, Pravinkumar, Uppal, Timsy, Pravinkumar Purushothaman, Timsy Uppal   +8 more
core   +1 more source

Sequencing of Kaposi's Sarcoma Herpesvirus (KSHV) genomes from persons of diverse ethnicities and provenances with KSHV-associated diseases demonstrate multiple infections, novel polymorphisms, and low intra-host variance.

PLoS Pathogens
Recently published near full-length KSHV genomes from a Cameroon Kaposi sarcoma case-control study showed strong evidence of viral recombination and mixed infections, but no sequence variations associated with disease.
Vickie A Marshall, Elena M Cornejo Castro, Charles A Goodman, Nazzarena Labo, Isabella Liu, Nicholas C Fisher, Kyle N Moore, Ananthakrishnan Nair, Taina Immonen, Brandon F Keele, Mark N Polizzotto, Thomas S Uldrick, Yunxiang Mu, Tanuja Saswat, Laurie T Krug, Kevin M McBride, Kathryn Lurain, Ramya Ramaswami, Robert Yarchoan, Denise Whitby   +19 more
doaj   +1 more source

Kaposi's sarcoma-associated herpesvirus (KSHV) gB dictates a low-pH endocytotic entry pathway as revealed by a dual-fluorescent virus system and a rhesus monkey rhadinovirus expressing KSHV gB.

PLoS Pathogens
Interaction with host cell receptors initiates internalization of Kaposi's sarcoma-associated herpesvirus (KSHV) particles. Fusion of viral and host cell membranes, which is followed by release of the viral capsid into the cytoplasm, is executed by the ...
Shanchuan Liu, Sarah Schlagowski, Anna K Großkopf, Natalia Khizanishvili, Xiaoliang Yang, Scott W Wong, Elina M Guzmán, Marija Backovic, Stefano Scribano, Arne Cordsmeier, Armin Ensser, Alexander S Hahn   +11 more
doaj   +1 more source