Results 71 to 80 of about 18,080 (165)

Differentially expressed metabolic genes in BJAB-KSHV and CoCl2 induced hypoxic BJAB/BJAB-KSHV cells compared to BJAB cells.

, 2018
(A) Venn diagram for up-regulated genes in BJAB-CoCl2/BJAB-KSHV/BJAB-KSHV-CoCl2 cells compared to BJAB cells. (B) Venn diagram for Down-regulated genes in BJAB-CoCl2/BJAB-KSHV/BJAB-KSHV-CoCl2 cells compared to BJAB cells.
Yonggang Pei (127281), Hem Chandra Jha (345436), Erle S. Robertson (177370), Rajnish Kumar Singh (5205032), Fengchao Lang (5205029)   +4 more
core   +1 more source

Selective autophagy impedes KSHV entry after recruiting the membrane damage sensor galectin-8 to virus-containing endosomes

Cell Reports
Summary: Kaposi sarcoma-associated herpesvirus (KSHV) is an oncogenic γ-herpesvirus. Autophagy during KSHV entry has remained unexplored. We show that LC3 lipidation as a hallmark of autophagy is induced shortly after KSHV entry.
Katarina Wendy Schmidt, Charlotte Montespan, Danielle Thompson, Miriam S. Lucas, Laure-Anne Ligeon, Harald Wodrich, Alexander S. Hahn, Urs F. Greber, Christian Münz   +8 more
doaj   +1 more source

Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres [PDF]

, 2020
To achieve replicative immortality, cancer cells must activate telomere maintenance mechanisms to prevent telomere shortening. ~85% of cancers circumvent telomeric attrition by re-expressing telomerase, while the remaining ~15% of cancers induce ...
Idilli, Aurora, Boulton, Simon J, Marzec, Paulina, Ojala, Paivi M, Feldhahn, Niklas, Farrell, Paul, Sarek, Grzegorz, Lippert, Tim, Bower, Mark   +8 more
core   +1 more source

Next‐Generation Sequencing Methods for Sensitive Hepatitis B Viral Genome Analysis: A European Study

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT This multicentre study investigated the utility of next‐generation sequencing (NGS) to detect and generate hepatitis B virus (HBV) genomes in samples of low viral load (from 0.2 to 6207 IU/mL). 23 HBV DNA‐positive plasma samples of genotypes A‐E and one HBV‐negative control sample were assayed blindly via 9 established NGS methods from 6 ...
Michael X. Fu, Maria F. Perdomo, Sheila F. Lumley, Johan Ringlander, Kai Kean, Kaitlin Reid, Richard Mayne, Oscar Enrique Torres Montaguth, Leysa Forrest, Sarah Buddle, Johannes C. Botha, Joakim B. Stenbäck, Zachery Dickson, Chris Kent, Haiting Chai, Matthew Byott, Leo Hannolainen, Shannah Secret, George Airey, Klaus Hedman, Monique I. Andersson, M. Azim Ansari, Eleni Nastouli, Judith Breuer, Philippa C. Matthews, Tanya Golubchik, William L. Irving, Peter Simmonds, Heli Harvala   +28 more
wiley   +1 more source

KSHV-induced ligand mediated activation of PDGF receptor-alpha drives Kaposi's sarcomagenesis [PDF]

, 2018
Kaposi’s sarcoma (KS) herpesvirus (KSHV) causes KS, an angiogenic AIDS-associated spindle-cell neoplasm, by activating host oncogenic signaling cascades through autocrine and paracrine mechanisms.
Cavallin, Lucas E., Julian Naipauer (5492984), Kurian, Mani, Sachin Gupta (528945), Julian Naipauer, Enrique A. Mesri (515944), Paola Locatelli, Goldschmidt-Clermont, Pascal J, Lucas E Cavallin, Sachin Gupta, Pascal J Goldschmidt-Clermont, Romanelli, Paolo, Gupta, Sachin, Paolo Romanelli (5492987), Locatelli, Paola, Mani Kurian (5492975), Lucas E. Cavallin (596052), Naipauer, Julian, Paola Locatelli (5492981), Pascal J. Goldschmidt-Clermont (268053), Paolo Romanelli, Mesri, Enrique A, Ma, Qi, Qi Ma (141685), Cavallin, Lucas E, Mani Kurian, Goldschmidt Clermont, Pascal J., Mehrdad Nadji (5492978), Qi Ma, Mehrdad Nadji, Nadji, Mehrdad, Mesri, Enrique Alfredo, Enrique A Mesri   +32 more
core   +1 more source

Microbial Signals in Cancer: Dissecting Host–Microbiota–Tumor Interactions and Potential Therapeutic Strategy

MedComm, Volume 7, Issue 9, September 2026.
Microbial signals from gut and tumor‐resident bacteria, fungi, viruses, and bacteriophages reshape immune and metabolic networks within the tumor microenvironment, thereby influencing cancer progression, treatment response. Therapeutic modulations, including dietary interventions, probiotics, antibiotics, fecal microbiota transplantation, engineered ...
Juan Lu, Mengjuan Xuan, Liang Yu, Zhongyang Xie, Qingfei Chu, Shihui Wei, Tuokai Wang, Chen Xue, Lanjuan Li   +8 more
wiley   +1 more source

Human Herpesvirus 8 Causes a Wide Spectrum of Disease in Liver Transplant Recipients and May be Donor Derived: Case Series and Systematic Review of an Emerging Challenge

Transplant Infectious Disease, Volume 28, Issue 5, September/October 2026.
Among 135 cases of post‐liver transplant HHV8 disease (4 from NSW), presentations varied, and mortality was high (44%). Donor screening was rare, and donor‐derived infection was suspected in 33%. Survival improved with mTORi, reduced immunosuppression, chemotherapy, and, for non‐KS disease, donor screening. ABSTRACT Background Human herpesvirus 8 (HHV8)
Karen M. J. Waller, Sudarshan Arvind, Simone I. Strasser, Ken Liu, Geoff W. McCaughan, David G. Bowen, Madeleine Gill, Rebecca Davis, William Rawlinson, Sacha Stelzer‐Braid, Geoff Watson, Vinay Vanguru, Tina Marinelli   +12 more
wiley   +1 more source

CONTROL OF STRESS RESPONSES BY VIRAL AND CELLULAR BASIC LEUCINE ZIPPER TRANSCRIPTION FACTORS

, 2022
Glycoproteins are processed through the secretory pathway and require folding in the endoplasmic reticulum (ER). When unfolded proteins accumulate in the ER, the sensor protein ATF6 is activated, translocated to the Golgi, and proteolytically processed ...
Stolz, Madeleine Lota
core  

Ginseng as a Functional Food Intervention for Interstitial Lung Disease: A Review of the Benefits and Molecular Mechanisms

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
From the perspectives of food science and nutrition, this article reviews the regulatory mechanisms through which ginseng and its major components influence ILD‐related pathological processes and discusses its potential as a functional food and future research directions. ABSTRACT Interstitial lung disease (ILD) encompasses a complex group of disorders
Jiahui Li, Guixin Di, Haijiao Wang, Mengzhu Chen, Keju Wang, Ziyuan Wang, Yanxin Li, Tan Wang   +7 more
wiley   +1 more source

Pathology of Kaposi's sarcoma-associated herpesvirus infection

Frontiers in Microbiology, 2011
Kaposi’s sarcoma-associated herpesvirus (KSHV, human herpesvirus 8, HHV-8) is a human herpesvirus, classified as a gamma-herpesvirus. KSHV is detected in Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and some cases of multicentric Castleman’s ...
Hitomi eFukumoto, Hitomi eFukumoto, Takayuki eKanno, Hideki eHasegawa, Harutaka eKatano   +4 more
doaj   +1 more source