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Chromatinization of the KSHV Genome During the KSHV Life Cycle [PDF]
Cancers, 2015 Kaposi’s sarcoma-associated herpesvirus (KSHV) belongs to the gamma herpesvirus family and is the causative agent of various lymphoproliferative diseases in humans.
Timsy Uppal +2 more
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KSHV LANA—The Master Regulator of KSHV Latency [PDF]
Viruses, 2014 Kaposi’s sarcoma associated herpesvirus (KSHV), like other human herpes viruses, establishes a biphasic life cycle referred to as dormant or latent, and productive or lytic phases. The latent phase is characterized by the persistence of viral episomes in a highly ordered chromatin structure and with the expression of a limited number of viral genes ...
Timsy Uppal +2 more
exaly +5 more sources
KSHV microRNAs: Tricks of the Devil [PDF]
Trends in Microbiology, 2017 Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), a vascular tumor frequently found in immunodeficient individuals. KSHV encodes 12 pre-microRNAs (pre-miRNAs), which are processed into 25 mature microRNAs (miRNAs).
Shou-Jiang Gao, Chun Lu, Wan Li
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SUMO and KSHV Replication [PDF]
Cancers, 2014 Small Ubiquitin-related MOdifier (SUMO) modification was initially identified as a reversible post-translational modification that affects the regulation of diverse cellular processes, including signal transduction, protein trafficking, chromosome segregation, and DNA repair.
Pei-Ching Chang
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Immunotherapy for KSHV-associated diseases
Current Opinion in Virology, 2022Kaposi sarcoma herpesvirus (KSHV)-associated diseases (Kaposi sarcoma, multicentric Castleman disease, primary effusion lymphoma, and KSHV inflammatory cytokine syndrome) are associated with immune suppression and dysregulation and loss of KSHV-specific immunity.
Kathryn, Lurain +2 more
openaire +2 more sources
Current Oncology Reports, 2005
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), has been linked to several malignancies in humans. KSHV is the etiologic agent associated with the development of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD). KSHV is a double-stranded DNA virus that has been
Blossom Damania
exaly +3 more sources
Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), has been linked to several malignancies in humans. KSHV is the etiologic agent associated with the development of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD). KSHV is a double-stranded DNA virus that has been
Blossom Damania
exaly +3 more sources
Regulation of KSHV Latency and Lytic Reactivation [PDF]
Viruses, 2020 Kaposi’s sarcoma-associated herpesvirus (KSHV) is associated with three malignancies— Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). Central to the pathogenesis of these diseases is the KSHV viral life cycle, which is composed of a quiescent latent phase and a replicative lytic phase.
Blossom Damania
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KSHV infection of B-cell lymphoma using a modified KSHV BAC36 and coculturing system
Journal of Microbiology, 2012Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of two B cell lymphoproliferative diseases, namely primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD). KSHV infection of B cell lymphoma in vitro has been a long-standing battle in advancing human KSHV biology.
Hyosun Cho, Hyojeung Kang
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2008
Kaposi’s sarcoma-associated herpesvirus (KSHV) has been consistently implicated in the pathogenesis of Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). The hallmark of KSHV infection is to establish life-long persistency that has imposed enormous pressure on this virus to escape host immune recognition.
Chengyu Liang +4 more
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Kaposi’s sarcoma-associated herpesvirus (KSHV) has been consistently implicated in the pathogenesis of Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). The hallmark of KSHV infection is to establish life-long persistency that has imposed enormous pressure on this virus to escape host immune recognition.
Chengyu Liang +4 more
openaire +1 more source
KSHV-like herpesviruses in chimps and gorillas
Nature, 2000Among the herpesviruses1, KSHV (Kaposi's-sarcoma-associated herpesvirus) is the human prototype of the rhadinovirus genus2. Rhadinoviruses (or γ2-herpesviruses) are found in several animal species, including New and Old World monkeys, but not in the great apes3,4,5.
V, Lacoste +5 more
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