Results 111 to 120 of about 69,810 (276)

Phenotypical and Functional Polymorphism of Liver Resident Macrophages

Cells, 2019
Liver diseases are one of the main causes of mortality. In this regard, the development of new ways of reparative processes stimulation is relevant. Macrophages play a leading role in the regulation of liver homeostasis in physiological conditions and in
Andrey V. Elchaninov, Timur Kh. Fatkhudinov, Polina A. Vishnyakova, Anastasia V. Lokhonina, Gennady T. Sukhikh   +4 more
doaj   +1 more source

Blood clearance and tissue distribution of PEGylated and non-PEGylated gold nanorods after intravenous administration in rats\ud [PDF]

, 2011
Aims: To develop and determine the safety of gold nanorods, whose aspect ratios can be tuned to obtain plasmon peaks between 650 and 850 nm, as contrast enhancing agents for diagnostic and therapeutic applications.
Jong, Wim H. de, Krystek, Petra, Lankveld, Danielle P.K., Leeuwen, Ton G. van, Manohar, Srirang, Oomen, Agnes G., Rayavarapu, Raja G., Verharen, Hennie W.   +7 more
core   +4 more sources

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Kupffer Cells [PDF]

The American Journal of Pathology, 2020
Elise Slevin, Leonardo Baiocchi, Nan Wu, Burcin Ekser, Keisaku Sato, Emily Lin, Ludovica Ceci, Lixian Chen, Sugeily R. Lorenzo, Wenjuan Xu, Konstantina Kyritsi, Victoria Meadows, Tianhao Zhou, Debiyoti Kundu, Yuyan Han, Lindsey Kennedy, Shannon Glaser, Heather Francis, Gianfranco Alpini, Fanyin Meng   +19 more
openaire   +2 more sources

High hepatic macrophage activation and low liver function in stable Wilson patients - a Danish cross-sectional study

Orphanet Journal of Rare Diseases, 2018
Background Hepatic macrophage (Kupffer cell) hyperplasia is often described in Wilson’s disease (WD). In many liver diseases, Kupffer cell activation is related to disease severity, liver function, and fibrosis but the importance in WD is unknown ...
Jessica Björklund, Tea Lund Laursen, Thomas Damgaard Sandahl, Holger Jon Møller, Hendrik Vilstrup, Peter Ott, Henning Grønbæk   +6 more
doaj   +1 more source

Role of liver endothelial and Kupffer cells in clearing low density lipoprotein from blood in hypercholesterolemic rabbits.

Journal of Lipid Research, 1992
The role of liver endothelial and Kupffer cells in the hepatic uptake of cholesterol-rich low density lipoprotein (LDL) was studied in rabbits fed a diet containing 2% (w/w) cholesterol for 3 weeks.
MS Nenseter, O Gudmundsen, N Roos, G Maelandsmo, CA Drevon, T Berg   +5 more
doaj   +1 more source

Monocytes mediate homing of circulating microvesicles to the pulmonary vasculature during low-grade systemic inflammation

Journal of Extracellular Vesicles, 2020
Microvesicles (MVs), a plasma membrane-derived subclass of extracellular vesicles, are produced and released into the circulation during systemic inflammation, yet little is known of cell/tissue-specific uptake of MVs under these conditions.
Kieran P. O’Dea, Ying Ying Tan, Sneh Shah, Brijesh V Patel, Kate C Tatham, Mike R. Wilson, Sanooj Soni, Masao Takata   +7 more
doaj   +1 more source

Eradication of unresectable liver metastasis through induction of tumour specific energy depletion. [PDF]

, 2019
Treatment of liver metastasis experiences slow progress owing to the severe side effects. In this study, we demonstrate a strategy capable of eliminating metastatic cancer cells in a selective manner.
Chen, Guojun, Chen, Qian, Gu, Zhen, Hu, Yong, Huo, Da, Jiang, Wei, Jiang, Xiqun, Luo, Xingyu, Zhang, Chao, Zhu, Jianfeng   +9 more
core  

Antimicrobial properties of Kupffer cells [PDF]

Infection and Immunity, 1988
To characterize the antimicrobial activities of Kupffer cells, I harvested macrophages from livers with a technique involving perfusion with collagenase and DNase. Ninety-nine percent of glass-adherent cells had typical macrophage morphology, 99% were esterase positive, and 60% phagocytosed opsonized zymosan when challenged with four particles per ...
openaire   +2 more sources