Results 91 to 100 of about 43,659 (221)

High hepatic macrophage activation and low liver function in stable Wilson patients - a Danish cross-sectional study

open access: yesOrphanet Journal of Rare Diseases, 2018
Background Hepatic macrophage (Kupffer cell) hyperplasia is often described in Wilson’s disease (WD). In many liver diseases, Kupffer cell activation is related to disease severity, liver function, and fibrosis but the importance in WD is unknown ...
Jessica Björklund   +6 more
doaj   +1 more source

Macrophage Membrane-Coated Nanoparticles Alleviate Hepatic Ischemia-Reperfusion Injury Caused by Orthotopic Liver Transplantation by Neutralizing Endotoxin

open access: yesInternational Journal of Nanomedicine, 2020
Zhibing Ou,1,* Hua Zhong,2,* Liang Zhang,2,3 Minghua Deng,2 Wenfeng Zhang,2 Jingyuan Wang,2 Huaguo Feng,2 Jianping Gong,2 Chunmu Miao,2 Zhujun Yi2 1Department of Hepatobiliary Surgery, Chenzhou No.1 People’s Hospital, Chenzhou, Hunan 410000, People&
Ou Z   +9 more
doaj  

Role of liver endothelial and Kupffer cells in clearing low density lipoprotein from blood in hypercholesterolemic rabbits.

open access: yesJournal of Lipid Research, 1992
The role of liver endothelial and Kupffer cells in the hepatic uptake of cholesterol-rich low density lipoprotein (LDL) was studied in rabbits fed a diet containing 2% (w/w) cholesterol for 3 weeks.
MS Nenseter   +5 more
doaj   +1 more source

Monocytes mediate homing of circulating microvesicles to the pulmonary vasculature during low-grade systemic inflammation

open access: yesJournal of Extracellular Vesicles, 2020
Microvesicles (MVs), a plasma membrane-derived subclass of extracellular vesicles, are produced and released into the circulation during systemic inflammation, yet little is known of cell/tissue-specific uptake of MVs under these conditions.
Kieran P. O’Dea   +7 more
doaj   +1 more source

Antimicrobial properties of Kupffer cells [PDF]

open access: yesInfection and Immunity, 1988
To characterize the antimicrobial activities of Kupffer cells, I harvested macrophages from livers with a technique involving perfusion with collagenase and DNase. Ninety-nine percent of glass-adherent cells had typical macrophage morphology, 99% were esterase positive, and 60% phagocytosed opsonized zymosan when challenged with four particles per ...
openaire   +2 more sources

Th2-Associated Alternative Kupffer Cell Activation Promotes Liver Fibrosis without Inducing Local Inflammation

open access: yesInternational Journal of Biological Sciences, 2011
Cirrhosis is the final outcome of liver fibrosis. Kupffer cell-mediated hepatic inflammation is considered to aggravate liver injury and fibrosis. Alternatively-activated macrophages are able to control chronic inflammatory events and trigger wound ...
Giuliana López-Navarrete, Espiridión Ramos-Martínez, Karina Suárez-Álvarez, Jesús Aguirre-García, Yadira Ledezma-Soto, Sonia León-Cabrera, Marco Gudiño-Zayas, Carolina Guzmán, Gabriela Gutiérrez-Reyes
doaj  

Functions of hepatic non-parenchymal cells in alcoholic liver disease

open access: yesLiver Research, 2019
Alcoholic liver disease (ALD) represents a wide spectrum of disease from simple steatosis to cirrhosis. Although there have been multiple attempts to treat ALD, its treatment is still based on abstinence from alcohol and using corticosteroids in ...
Won-Mook Choi   +2 more
doaj   +1 more source

Effects of zinc oxide nanoparticles on Kupffer cell phagosomal motility, bacterial clearance, and liver function

open access: yesInternational Journal of Nanomedicine, 2015
Christa Y Watson, Ramon M Molina, Andressa Louzada, Kimberly M Murdaugh, Thomas C Donaghey, Joseph D BrainCenter for Nanotechnology and Nanotoxicology, Molecular and Integrative Physiological Sciences Program, Department of Environmental Health ...
Watson CY   +5 more
doaj  

Characterisation of Kupffer cells in some Amphibia

open access: yesJournal of Anatomy, 2000
A study on the Kupffer cells (KCs) of Amphibia was undertaken in order to compare these cells with those of endothermic animals. Liver tissue and isolated and cultured KCs were studied by light microscopy and by transmission and scanning electron microscopy.
C, Corsaro   +4 more
openaire   +3 more sources

Kupffer Cells in Health and Disease

open access: yes, 2014
Kupffer cells (KC), the resident macrophages of the liver, represent the largest population of mononuclear phagocytes in the body. Phenotypic, developmental, and functional aspects of these cells in steady state and in different diseases are the focus of this review.
Woltman, Andrea   +3 more
openaire   +1 more source

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