Results 71 to 80 of about 46,673 (194)

Apolipoprotein E is secreted by cultured lipocytes of the rat liver.

Journal of Lipid Research, 1991
Hepatic lipocytes, the retinoid-storing cells of the liver, share several characteristics with vascular smooth muscle cells. To determine whether they also share the characteristic of apolipoprotein E secretion, we have compared the relative mRNA ...
G Friedman, LM Liu, SL Friedman, JK Boyles   +3 more
doaj   +1 more source

TMEM16F Expressed in Kupffer Cells Regulates Liver Inflammation and Metabolism to Protect Against Listeria Monocytogenes

Advanced Science
Infection by bacteria leads to tissue damage and inflammation, which need to be tightly controlled by host mechanisms to avoid deleterious consequences.
Jianlong Tang, Hua Song, Shimin Li, Sin Man Lam, Jieming Ping, Mengyun Yang, Na Li, Teding Chang, Ze Yu, Weixiang Liu, Yan Lu, Min Zhu, Zhaohui Tang, Zheng Liu, Yusong R. Guo, Guanghou Shui, André Veillette, Zhutian Zeng, Ning Wu   +18 more
doaj   +1 more source

Kupffer Cells Promote Hepatic Steatosis Via Interleukin-1 beta-Dependent Suppression of Peroxisome Proliferator-Activated Receptor alpha Activity [PDF]

, 2009
Contains fulltext : 87859.pdf (Publisher’s version ) (Open Access)Kupffer cells have been implicated in the pathogenesis of various liver diseases.
Rooijen, Nico, van, Stienstra, R., Fredy Saudale, van Rooijen, Nico, Rinke Stienstra, van Rooijen, N., Duval, C., Bart Staels, Müller, M.R., Keshtkar, S., Kersten, S., Muller, M., Groener, J.E.M., Stienstra, Rinke, Nico van Rooijen, Kersten, Sander, Groener, C., Staels, B., Kersten, A.H., Müller, Michael, Saudale, Fredy, Johanna E. M. Groener, Sander Kersten, Michael Müller, Groener, Johanna E., Duval, C.N.C., Staels, Bart, Rooijen, N. van, Keshtkar, Shohreh, Caroline Duval, Duval, Caroline, Shohreh Keshtkar, Saudale, F., Groener, Johanna E. M., Rooijen, N., van   +34 more
core   +1 more source

A Coculture Model of Intrahepatic Islet Transplantation: Activation of Kupffer Cells by Islets and Acinar Tissue

Cell Transplantation, 2001
Clinical and experimental studies of intrahepatic islet transplantation have allowed histological and systemic observations to be made, but the location of the transplanted islets makes it difficult to assess direct effects on the cells of the liver.
Heather A. Clayton, Joanna E. Davies, Chris D. Sutton, Peter R. F. Bell, Ashley R. Dennison   +4 more
doaj   +1 more source

Macrophage Membrane-Coated Nanoparticles Alleviate Hepatic Ischemia-Reperfusion Injury Caused by Orthotopic Liver Transplantation by Neutralizing Endotoxin

International Journal of Nanomedicine, 2020
Zhibing Ou,1,* Hua Zhong,2,* Liang Zhang,2,3 Minghua Deng,2 Wenfeng Zhang,2 Jingyuan Wang,2 Huaguo Feng,2 Jianping Gong,2 Chunmu Miao,2 Zhujun Yi2 1Department of Hepatobiliary Surgery, Chenzhou No.1 People’s Hospital, Chenzhou, Hunan 410000, People&
Ou Z, Zhong H, Zhang L, Deng M, Zhang W, Wang J, Feng H, Gong J, Miao C, Yi Z   +9 more
doaj  

Phenotypical and Functional Polymorphism of Liver Resident Macrophages

Cells, 2019
Liver diseases are one of the main causes of mortality. In this regard, the development of new ways of reparative processes stimulation is relevant. Macrophages play a leading role in the regulation of liver homeostasis in physiological conditions and in
Andrey V. Elchaninov, Timur Kh. Fatkhudinov, Polina A. Vishnyakova, Anastasia V. Lokhonina, Gennady T. Sukhikh   +4 more
doaj   +1 more source

Upregulation of Kupffer cell β-adrenoceptors and cAMP levels during the late stage of sepsis [PDF]

, 1998
Although a burst of immunoresponsiveness may occur during the early stage of sepsis, late sepsis is characterized by severe immunodepression. In addition, although studies have shown that stimulation of macrophage β-adrenoceptors results in an increase ...
Hahn, Peter Y., Chaudry, Irshad H., Ba, Zheng F., Yoo, Peter, Wang, Ping   +4 more
core   +1 more source

Kupffer Cells [PDF]

The American Journal of Pathology, 2020
Elise Slevin, Leonardo Baiocchi, Nan Wu, Burcin Ekser, Keisaku Sato, Emily Lin, Ludovica Ceci, Lixian Chen, Sugeily R. Lorenzo, Wenjuan Xu, Konstantina Kyritsi, Victoria Meadows, Tianhao Zhou, Debiyoti Kundu, Yuyan Han, Lindsey Kennedy, Shannon Glaser, Heather Francis, Gianfranco Alpini, Fanyin Meng   +19 more
openaire   +2 more sources

An efficient method to isolate Kupffer cells eliminating endothelial cell contamination and selective bias [PDF]

, 2018
Multi-colour flow cytometry and cell-sorting are powerful immunological tools for the study of hepatic macrophages, yet there is no consensus on the optimal method to prepare liver homogenates for these analyses.
Lynch, Ruairi, Pellicoro, Antonella, Iredale, John, Antonella Pellicoro, Jenkins, Stephen, Catherine A Hawley, Stephen J Jenkins, Hawley, Catherine A, Bain, Calum, Ruairi W Lynch, Calum C Bain, John P Iredale   +11 more
core   +1 more source

High hepatic macrophage activation and low liver function in stable Wilson patients - a Danish cross-sectional study

Orphanet Journal of Rare Diseases, 2018
Background Hepatic macrophage (Kupffer cell) hyperplasia is often described in Wilson’s disease (WD). In many liver diseases, Kupffer cell activation is related to disease severity, liver function, and fibrosis but the importance in WD is unknown ...
Jessica Björklund, Tea Lund Laursen, Thomas Damgaard Sandahl, Holger Jon Møller, Hendrik Vilstrup, Peter Ott, Henning Grønbæk   +6 more
doaj   +1 more source