Results 61 to 70 of about 46,673 (194)

Targeting of naproxen covalently linked to HSA to sinusoidal cell types of the liver [PDF]

, 1997
We have coupled the anti-inflammatory drug naproxen (Nap) covalently to human serum albumin (HSA) to deliver this drug selectively to non parenchymal cell types of the liver during endotoxin induced hepatic inflammation.
Melgert, BN; id_orcid, Albrecht, C, Wartna, E, Reichen, J, Molema, G; id_orcid, Poelstra, K; id_orcid, Lebbe, C, Meijer, DKF   +7 more
core   +4 more sources

KUPFFER HÜCRESİ

Cerrahpaşa Medical Journal, 2014
Background.- Kupffer cells were firstly described by von Kupffer at 1876. In our work we reviewed the function and properties of these cells especially other than fagocytosis whom are cell-cell communication and some clinical importances of these ...
Tahsin Murad AKTAN, Aydan CANBİLEN, Nurullah KEKLİKOĞLU   +2 more
doaj  

A broadly adaptable protocol for isolating Kupffer cells from non-model species: application to Mastomys natalensis and its susceptibility to Old World mammarenaviruses

Frontiers in Immunology
BackgroundKupffer cells are specialized, liver-resident macrophages that play central roles in hepatic homeostasis, immune surveillance and pathogen clearance.
Nicolas Corrales, Katharina Hansen-Kant, Angelika Lander, Joseph B. Prescott   +3 more
doaj   +1 more source

The interaction of ceruloplasmin with Kupffer cells.

European journal of cell biology, 1990
The binding and uptake of ceruloplasmin was studied with rat liver cells using gold-labeled probes. Ceruloplasmins from either rat or sheep were used, in which different molecular conformations had been induced according to established biochemical criteria.
DINI L, CARBONARO M, MUSCI, Giovanni, CALABRESE L.   +3 more
openaire   +4 more sources

Kupffer cell-mediated hepatic injury induced by silica nanoparticles in vitro and in vivo [PDF]

, 2013
Qingqing Chen, Yang Xue, Jiao SunShanghai Biomaterials Research and Testing Center, Shanghai Key Laboratory of Stomatology, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of ...
Chen Q, Sun J, Xue Y
core  

Kupffer cell

Citation: 'Kupffer cell' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13367 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
Mark D Stringer, Seyed Ali Mirjalili
openaire   +2 more sources

Kupffer Cells Promote the Differentiation of Adult Liver Hematopoietic Stem and Progenitor Cells into Lymphocytes via ICAM-1 and LFA-1 Interaction

Stem Cells International, 2019
It has been reported that the adult liver contains hematopoietic stem and progenitor cells (HSPCs), which are associated with long-term hematopoietic reconstitution activity.
Deping Meng, Yuhong Qin, Nan Lu, Keke Fang, Yuan Hu, Zhigang Tian, Cai Zhang   +6 more
doaj   +1 more source

Targeting of liposomes to sinusoidal liver cells:Massive uptake by liver endothelial cells via a scavenger receptor mediated process [PDF]

, 1997
Human serum albumin (HSA) derivatized with cis-aconitic anhydride (Aco-HSA) was covalently coupled to liposomes (Aco-HSA-Lip). Aco-HSA-Lip were cleared from the blood and taken up by the liver within 30 minutes after injection into a rat.
Morselt, HWM, Kamps, JAAM; id_orcid, Swart, PJ, Scherphof, GL, Meijer, DKF   +4 more
core   +4 more sources

The Antidepressant Mirtazapine Activates Hepatic Macrophages, Facilitating Pathogen Clearance While Limiting Tissue Damage in Mice

Frontiers in Immunology, 2020
Background and AimsMirtazapine is an atypical antidepressant with antagonist activity for serotonin and histamine receptors. Clinical and experimental evidence suggests that, in addition to treating depression, mirtazapine also alters liver innate ...
Rachelle Paige Davis, Rachelle Paige Davis, Wagdi Almishri, Wagdi Almishri, Craig Neal Jenne, Craig Neal Jenne, Mark Gordon Swain, Mark Gordon Swain   +7 more
doaj   +1 more source

3D co-cultures of primary human hepatocytes and Kupffer-like cells to address innate immune responses to rAAV

Scientific Reports
Recombinant adeno-associated viruses (rAAVs) are a platform of choice for gene therapy. However, liver-directed transduction has been hindered by immune responses unpredicted in the pre-clinical models, resulting in therapy failure.
Isabella Ramella Gal, Francisca Arez, Inês P. Correia, Giacomo Domenici, Sofia Fernandes, Gabriela Silva, Inês Saldanha, Nadia Duarte, Catarina Freitas, Paula M. Alves, Udo Maier, Ana Sofia Coroadinha, François du Plessis, Catarina Brito   +13 more
doaj   +1 more source