Results 81 to 90 of about 46,673 (194)

Role of liver endothelial and Kupffer cells in clearing low density lipoprotein from blood in hypercholesterolemic rabbits.

open access: yesJournal of Lipid Research, 1992
The role of liver endothelial and Kupffer cells in the hepatic uptake of cholesterol-rich low density lipoprotein (LDL) was studied in rabbits fed a diet containing 2% (w/w) cholesterol for 3 weeks.
MS Nenseter   +5 more
doaj   +1 more source

Monocytes mediate homing of circulating microvesicles to the pulmonary vasculature during low-grade systemic inflammation

open access: yesJournal of Extracellular Vesicles, 2020
Microvesicles (MVs), a plasma membrane-derived subclass of extracellular vesicles, are produced and released into the circulation during systemic inflammation, yet little is known of cell/tissue-specific uptake of MVs under these conditions.
Kieran P. O’Dea   +7 more
doaj   +1 more source

Antimicrobial properties of Kupffer cells [PDF]

open access: yesInfection and Immunity, 1988
To characterize the antimicrobial activities of Kupffer cells, I harvested macrophages from livers with a technique involving perfusion with collagenase and DNase. Ninety-nine percent of glass-adherent cells had typical macrophage morphology, 99% were esterase positive, and 60% phagocytosed opsonized zymosan when challenged with four particles per ...
openaire   +2 more sources

Isolation and primary culture of rat Kupffer cells [PDF]

open access: yes, 1998
The aim of this study was to describe a reproducible method for the isolation, purification and primary culture of rat Kupffer cells. Kupffer cells were isolated following sequential pronase/collagenase digestion of the liver and enrichment of a non ...
Olynyk, J.K., Clarke, S.L.
core  

Role of PINCH and Its Partner Tumor Suppressor Rsu-1 in Regulating Liver Size and Tumorigenesis [PDF]

open access: yes, 2013
Particularly interesting new cysteine-histidine-rich protein (PINCH) protein is part of the ternary complex known as the IPP (integrin linked kinase (ILK)-PINCH-Parvin-α) complex.
Bhave, VS   +25 more
core   +1 more source

Kupffer cells induce liver progenitor cell proliferation in response to CDE diet-induced liver injury [PDF]

open access: yes, 2012
Background We have previously shown that both resident Kupffer cell and infiltrating monocyte-derived macrophage numbers increase in the liver in response to injury induced by the CDE diet.(1) The Kupffer cells and infiltrating macrophages are located ...
Elsegood, C., Yeoh, G., Olynyk, J.
core  

Th2-Associated Alternative Kupffer Cell Activation Promotes Liver Fibrosis without Inducing Local Inflammation

open access: yesInternational Journal of Biological Sciences, 2011
Cirrhosis is the final outcome of liver fibrosis. Kupffer cell-mediated hepatic inflammation is considered to aggravate liver injury and fibrosis. Alternatively-activated macrophages are able to control chronic inflammatory events and trigger wound ...
Giuliana López-Navarrete, Espiridión Ramos-Martínez, Karina Suárez-Álvarez, Jesús Aguirre-García, Yadira Ledezma-Soto, Sonia León-Cabrera, Marco Gudiño-Zayas, Carolina Guzmán, Gabriela Gutiérrez-Reyes
doaj  

Functions of hepatic non-parenchymal cells in alcoholic liver disease

open access: yesLiver Research, 2019
Alcoholic liver disease (ALD) represents a wide spectrum of disease from simple steatosis to cirrhosis. Although there have been multiple attempts to treat ALD, its treatment is still based on abstinence from alcohol and using corticosteroids in ...
Won-Mook Choi   +2 more
doaj   +1 more source

Scanning electron microscopic analysis of Kupffer cell proliferation after zymosan administration. [PDF]

open access: yes, 1984
Rat Kupffer cells were observed and counted under a scanning electron microscope after a single dose of zymosan. The cell number increased after 24 h and reached 2 times the control after 72 h.
Kawaguchi, Kenji
core   +1 more source

Adaptive Kupffer cell alterations after femur fracture trauma in rats [PDF]

open access: yes, 1997
Because Kupffer cells constitute the largest fixed macrophage population and reside at a strategic position in hepatic sinusoids, interacting with hepatocytes, circulating cells, and mediators from the gut, they may be important in the inflammatory ...
L. W. Bracey   +3 more
core   +1 more source

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