Results 81 to 90 of about 46,673 (194)
The role of liver endothelial and Kupffer cells in the hepatic uptake of cholesterol-rich low density lipoprotein (LDL) was studied in rabbits fed a diet containing 2% (w/w) cholesterol for 3 weeks.
MS Nenseter +5 more
doaj +1 more source
Microvesicles (MVs), a plasma membrane-derived subclass of extracellular vesicles, are produced and released into the circulation during systemic inflammation, yet little is known of cell/tissue-specific uptake of MVs under these conditions.
Kieran P. O’Dea +7 more
doaj +1 more source
Antimicrobial properties of Kupffer cells [PDF]
To characterize the antimicrobial activities of Kupffer cells, I harvested macrophages from livers with a technique involving perfusion with collagenase and DNase. Ninety-nine percent of glass-adherent cells had typical macrophage morphology, 99% were esterase positive, and 60% phagocytosed opsonized zymosan when challenged with four particles per ...
openaire +2 more sources
Isolation and primary culture of rat Kupffer cells [PDF]
The aim of this study was to describe a reproducible method for the isolation, purification and primary culture of rat Kupffer cells. Kupffer cells were isolated following sequential pronase/collagenase digestion of the liver and enrichment of a non ...
Olynyk, J.K., Clarke, S.L.
core
Role of PINCH and Its Partner Tumor Suppressor Rsu-1 in Regulating Liver Size and Tumorigenesis [PDF]
Particularly interesting new cysteine-histidine-rich protein (PINCH) protein is part of the ternary complex known as the IPP (integrin linked kinase (ILK)-PINCH-Parvin-α) complex.
Bhave, VS +25 more
core +1 more source
Kupffer cells induce liver progenitor cell proliferation in response to CDE diet-induced liver injury [PDF]
Background We have previously shown that both resident Kupffer cell and infiltrating monocyte-derived macrophage numbers increase in the liver in response to injury induced by the CDE diet.(1) The Kupffer cells and infiltrating macrophages are located ...
Elsegood, C., Yeoh, G., Olynyk, J.
core
Cirrhosis is the final outcome of liver fibrosis. Kupffer cell-mediated hepatic inflammation is considered to aggravate liver injury and fibrosis. Alternatively-activated macrophages are able to control chronic inflammatory events and trigger wound ...
Giuliana López-Navarrete, Espiridión Ramos-Martínez, Karina Suárez-Álvarez, Jesús Aguirre-García, Yadira Ledezma-Soto, Sonia León-Cabrera, Marco Gudiño-Zayas, Carolina Guzmán, Gabriela Gutiérrez-Reyes
doaj
Functions of hepatic non-parenchymal cells in alcoholic liver disease
Alcoholic liver disease (ALD) represents a wide spectrum of disease from simple steatosis to cirrhosis. Although there have been multiple attempts to treat ALD, its treatment is still based on abstinence from alcohol and using corticosteroids in ...
Won-Mook Choi +2 more
doaj +1 more source
Scanning electron microscopic analysis of Kupffer cell proliferation after zymosan administration. [PDF]
Rat Kupffer cells were observed and counted under a scanning electron microscope after a single dose of zymosan. The cell number increased after 24 h and reached 2 times the control after 72 h.
Kawaguchi, Kenji
core +1 more source
Adaptive Kupffer cell alterations after femur fracture trauma in rats [PDF]
Because Kupffer cells constitute the largest fixed macrophage population and reside at a strategic position in hepatic sinusoids, interacting with hepatocytes, circulating cells, and mediators from the gut, they may be important in the inflammatory ...
L. W. Bracey +3 more
core +1 more source

