Results 181 to 190 of about 50,401 (271)

Commentary on "Desialylated Platelets Maintain Immune Quiescence through Regulating Kupffer Cells". [PDF]

Research (Wash D C), 2023
Li C, Morrell CN.
europepmc   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, Volume 293, Issue 13, Page 3717-3757, July 2026.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Infiltrating macrophages replace Kupffer cells and play diverse roles in severe alcohol-associated hepatitis. [PDF]

Cell Mol Immunol
Wang Y, Guan Y, Feng D, Maccioni L, Parra MA, Peiffer B, Mackowiak B, Kuwabara T, Mori K, Mukoyama M, Bataller R, Sun Z, Gao B.   +12 more
europepmc   +1 more source

RNA‐based CLEM (RCLEM) bridging RNA localisation and ultrastructural mapping in 3D

Journal of Microscopy, Volume 303, Issue 1, Page 120-131, July 2026.
Abstract Spatial transcriptomics and in situ hybridisation techniques have become essential for contextualising single‐cell RNA sequencing (scRNA‐seq) data by mapping cell type– and state–specific mRNA expression within intact tissues. Beyond validating scRNA‐seq predictions, these spatial methods provide critical insight into the localisation of ...
Daan Verhaege, Lore Van Acker, Camille Wagner, Yentl Van den Berghe, Jérémy Verbeke, Martin Guilliams, Anna Kremer, Lien Van Hoecke, Roosmarijn E Vandenbroucke   +8 more
wiley   +1 more source

C/EBPβ-VCAM1 axis in Kupffer cells promotes hepatic inflammation in MASLD. [PDF]

JHEP Rep
Lin SZ, Xie Y, Cheng YQ, Xue R, Su YS, Liu M, Chen YW, Fan JG.   +7 more
europepmc   +1 more source

Repopulating Kupffer cells originate directly from hematopoietic stem cells. [PDF]

Stem Cell Res Ther, 2023
Fan X, Lu P, Cui XH, Wu P, Lin WR, Zhang D, Yuan SZ, Liu B, Chen FY, You H, Wei HD, He FC, Jia JD, Jiang Y.   +13 more
europepmc   +1 more source

From EM to AI: Multiscale imaging of the secretory pathway with insights from plant cells

Journal of Microscopy, Volume 303, Issue 1, Page 3-20, July 2026.
Abstract The secretory pathway is a central and evolutionarily conserved feature of eukaryotic cells, responsible for protein and lipid trafficking, membrane biogenesis, signalling, and cellular homeostasis. Its complexity, dynamic behaviour, and nanoscale organisation have made it a longstanding target of microscopy‐driven investigation.
Charlotte Pain, Emily Farley
wiley   +1 more source

Kupffer Cells Regulate iNKT Cells Through Il-12 to Mitigate the Extent of APAP-Induced Damage in the Liver. [PDF]

J Cell Mol Med
Li Y, Wen S, Liu J, Li S, Shi J, Wang H.
europepmc   +1 more source

Role of Kupffer cells in tolerance induction after liver transplantation. [PDF]

Front Cell Dev Biol, 2023
Zheng W, Yang L, Jiang S, Chen M, Li J, Liu Z, Wu Z, Gong J, Chen Y.   +8 more
europepmc   +1 more source

Role of Gram‐Negative Bacterial Infections in Acute‐On‐Chronic Liver Failure

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Acute‐on‐chronic liver failure (ACLF) is a systemic disease characterised by an acute clinical deterioration of pre‐existing liver cirrhosis leading to multiple organ failure due to systemic inflammation. It may be triggered by the translocation of bacteria and bacterial compounds across the gut barrier.
Camilla Cadoli, Volker Müller, Christoph Welsch, Heiko Mühl, Jonel Trebicka, Volkhard A. J. Kempf   +5 more
wiley   +1 more source