Results 181 to 190 of about 74,691 (293)

Role of Kupffer cells in tolerance induction after liver transplantation. [PDF]

Front Cell Dev Biol, 2023
Zheng W, Yang L, Jiang S, Chen M, Li J, Liu Z, Wu Z, Gong J, Chen Y.   +8 more
europepmc   +1 more source

Mitochondrial DNA: A Key Alarmin Igniting the Inflammasome Fire in Health and Disease

Immunology, Volume 178, Issue 2, Page 218-230, June 2026.
This review illustrates how mitochondrial DNA, released under cellular stress, acts as a key alarmin that ignites innate immune sensors, particularly inflammasomes and the cGAS‐STING pathway. This paper details how this sustained “inflammasome fire” fuels the progression of diverse inflammatory diseases, including neurodegeneration and metabolic ...
Woo Hyun Park
wiley   +1 more source

CHB-Induced Immune Zonation Chaos Elicited LXRα-mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation. [PDF]

Adv Sci (Weinh)
Shi J, Li Q, Li J, Bai J, Xi J, He Q, Zhou J, Wang X, Song X, Li X, Yue X, Zhang X, Sun Z, Li J, Yang W, Cui Y, Shu W, Guo L, Wang S.   +18 more
europepmc   +1 more source

Induction of Clinical Operational Tolerance Through Immunosuppression Minimization: Less Is More?

Liver International, Volume 46, Issue 6, June 2026.
ABSTRACT The goal of achieving clinical operational tolerance in liver transplantation has sparked significant interest, driven by the desire to mitigate the long‐term adverse effects of immunosuppression. Advances in understanding the immunological mechanisms underpinning operational tolerance in liver transplantation have highlighted the central role
Emilia Knioła, Bartosz Foroncewicz, Jan Lerut, Leszek Pączek, Krzysztof Mucha   +4 more
wiley   +1 more source

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

Advanced Functional Materials, Volume 36, Issue 36, 4 May 2026.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova, Ivan V. Zelepukin, Lyubov V. Gorelik, Anton L. Popov, Andrei I. Pastukhov, Gleb V. Tikhonowski, Maxim S. Savinov, Danil D. Kolmanovich, Nikita A. Pivovarov, Alina Yu. Kapitannikova, Anton A. Popov, Anna S. Sogomonyan, Vsevolod A. Skribitsky, Aziz B. Mirkasymov, Andrei V. Kabashin, Sergey M. Deyev   +15 more
wiley   +1 more source

Mannose-Conjugated Cholesterol Containing Lipid Nanoparticles for Active Targeted mRNA Delivery to Liver Sinusoidal Endothelial and Kupffer Cells. [PDF]

Bioconjug Chem
Kim Y, Chatterjee S, Robertson AL, Guerrero ED, Vaidya A, Wang X, Lee SM, Wei J, Miller WE, Farbiak L, Siegwart DJ.   +10 more
europepmc   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, Volume 15, Issue 17, 8 May 2026.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Transcriptomic profiling of Kupffer cells exposed to <i>Clonorchis sinensis</i> extracellular vesicles: Unraveling the role of <i>CSF</i>3 in hepatic fibrosis. [PDF]

Food Waterborne Parasitol
Lan Z, Wang X, Zhang Y, Zhou L, Bai X, Zhang X, Zhang H, Qiu H, Gao J, Cheng G, Wang C.   +10 more
europepmc   +1 more source

Comparison of JB4 plastic resin and standard paraffin methods on student performance and student perspectives in digital histology education: A randomized controlled study

Anatomical Sciences Education, Volume 19, Issue 5, Page 723-731, May 2026.
Abstract This randomized controlled study compared the effectiveness of histological preparations embedded in glycol methacrylate‐based JB4 plastic resin with traditional paraffin blocks in digital histology education. A total of 297 second‐year medical students at Sivas Cumhuriyet University participated.
Zeynep Deniz Şahin İnan, Ezgi Ağadayı   +1 more
wiley   +1 more source

A Novel Function of Glycerol Kinase Alleviates LPS-Induced Inflammatory Responses by the p38/STAT3 Pathway and Mitigates ROS Generation in Kupffer Cells. [PDF]

Antioxidants (Basel)
Li Y, Zhang X, Wang D, Fan G, Yang X.
europepmc   +1 more source