Results 181 to 190 of about 45,372 (255)

RNase T2 deficiency promotes TLR13-dependent replenishment of tissue-protective Kupffer cells. [PDF]

J Exp Med
Sato R, Liu K, Shibata T, Hoshino K, Yamaguchi K, Miyazaki T, Hiranuma R, Fukui R, Motoi Y, Fukuda-Ohta Y, Zhang Y, Reuter T, Ishida Y, Kondo T, Chiba T, Asahara H, Taoka M, Yamauchi Y, Isobe T, Kaisho T, Furukawa Y, Latz E, Nakatani K, Izumi Y, Nie Y, Taniguchi H, Miyake K.   +26 more
europepmc   +1 more source

Applications of Bioinorganic Nano‐Based Delivery Systems—Diagnostics and Therapeutics

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Nanotechnology has emerged as a promising avenue for producing nanomedicines as alternatives to conventional drugs. Many organic nanoparticles, such as liposomes used in formulations like Doxil, Onivyde, and Marqibo, are approved by the Food and Drug Administration (FDA) and instrumental in treating various types of cancers.
Frank Ssengooba, Jubilee Andrew, Donald Fernandes   +2 more
wiley   +1 more source

Loss of embryonically-derived Kupffer cells during hypercholesterolemia accelerates atherosclerosis development. [PDF]

Nat Commun
Fima R, Dussaud S, Benbida C, Blanchet M, Lanthiez F, Poupel L, Brambilla C, Gélineau A, Dessena M, Blanc M, Lerévérend C, Moreau M, Boissonnas A, Gautier EL, Huby T.   +14 more
europepmc   +1 more source

Beyond Weight Loss: Tirzepatide as a Metabolic Disease‐Modifying Strategy for Metabolic Dysfunction‐Associated Steatohepatitis: A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide and a major contributor to liver‐related morbidity and mortality. Its progressive subtype, metabolic dysfunction–associated steatohepatitis (MASH), is characterized by hepatocellular injury, inflammation,
Zubaier Ahmed, Nashrah Mustafa, Tamanna Sarkar, Hasina Yasmin   +3 more
wiley   +1 more source

RNA m⁶A-mediated post-transcriptional repression of glucocorticoid receptor in LPS-activated Kupffer cells on broilers. [PDF]

Poult Sci
Zhao Y, Jiang Y, Feng Y, Zhao R.
europepmc   +1 more source

The Therapeutic Potential of H2S‐Releasing Platforms in Cardiovascular Applications

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 8, August 2026.
The Therapeutic Potential of H2S‐Releasing Platforms. ABSTRACT Once known as a toxic gas, hydrogen sulfide (H2S) is now making its way into many therapeutic applications. Similar to its other fellow endogenous gasotransmitters, nitric oxide and carbon monoxide, H2S is a small gas with a short half‐life, making it extremely capable of penetrating ...
Tia N. Shorter, Elizabeth J. Brisbois
wiley   +1 more source

Complement 3a receptor 1 on macrophages and Kupffer cells is not required for the pathogenesis of metabolic dysfunction-associated steatotic liver disease. [PDF]

Elife
Homan EA, Gilani A, Rubio-Navarro A, Johnson MA, Schaepkens OM, Cortada E, Pereira de Lima R, Stoll L, Lo JC.   +8 more
europepmc   +1 more source

Atorvastatin Reduces Alcohol‐Related Cardiac and Liver Tissue Damage, Oxidative Stress, Inflammation, Apoptosis, and Thiol‐Disulfide Imbalance in Rats

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Atorvastatin (40 mg/kg) inhibited fibrosis, hypertrophy, apoptosis, inflammation, and oxidative stress caused by alcohol consumption. It may contribute to the regulation of mitochondrial function and thiol/disulfide balance by limiting alcohol‐related heart and liver damage.
Cumaali Demirtas, Şahhan Kılıç, Mert Babaoğlu, Süha Asal, Elif Gökçe Tenekeci, Hakan Beyaztaş, Eray Metin Guler, Salime Pelin Erguven, Kubra Sevgin   +8 more
wiley   +1 more source

CD4⁺ T cells license Kupffer cells to reverse CD8⁺ T cell dysfunction induced by hepatocellular priming. [PDF]

Nat Immunol
Venzin V, Beccaria CG, Perucchini C, Delfino P, Bono EB, Giustini L, Moalli F, Grillo M, Fumagalli V, Laura C, Di Lucia P, Reinhard K, Petschenka J, Omokoko TA, Celant A, Ottolini S, Kawashima K, Ravà M, De Giovanni M, Inverso D, Kuka M, Kennedy PTF, Guilliams M, Casorati G, Pedica F, Ponzoni M, Şahin U, Le Bert N, Bertoletti A, Vascotto F, Guidotti LG, Iannacone M.   +31 more
europepmc   +1 more source

Lifestyle Factors and Thromboembolic Risk in Atrial Fibrillation: Age‐Dependent Effects of Smoking and Alcohol Consumption

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
Association of current smoking and daily alcohol consumption with cardioembolic stroke in patients with atrial fibrillation. ABSTRACT Background Atrial fibrillation (AF) relates to cardioembolic stroke (CS), but the role of lifestyle factors, including smoking and alcohol, remains unclear.
Masamichi Yano, Yasuyuki Egami, Mikako Kise, Taichi Mukai, Noriyuki Kobayashi, Ayako Sugino, Masaru Abe, Hiroaki Nohara, Shodai Kawanami, Koji Yasumoto, Naotaka Okamoto, Yasuharu Matsunaga‐Lee, Masami Nishino   +12 more
wiley   +1 more source