Results 231 to 240 of about 74,691 (293)

Xenoperfusion—The Transformative Role of Machine Perfusion in Xenotransplantation

Xenotransplantation, Volume 33, Issue 3, May/June 2026.
ABSTRACT Recent advances in xenotransplantation have gained substantial public and clinical attention as genetically modified porcine organs are now being transplanted into living human recipients. While only case reports have been published to date, the first clinical trials for kidney xenotransplantation are now ongoing.
Florian Huwyler, Simon Stoerzer, Pierre‐Alain Clavien, Mark W. Tibbitt   +3 more
wiley   +1 more source

Targeted Sodium Acetate Liposomes for Hepatocytes and Kupffer Cells: An Oral Dual-Targeted Therapeutic Approach for Non-Alcoholic Fatty Liver Disease Alleviation. [PDF]

Nutrients
Hou Y, Gao X, Gong J, Dong X, Hao Y, Zhai Z, Zhang H, Zhang M, Liu R, Wang R, Zhao L.   +10 more
europepmc   +1 more source

Postbiotics lower adipose tissue MHCII inflammation and blood glucose in obese mice, dependent on sex

Physiological Reports, Volume 14, Issue 10, May 2026.
Postbiotics lower adipose tissue MHCII inflammation and improve blood glucose control in male mice during obesity. Abstract Obesity is characterized by compartmentalized inflammation in metabolic tissues and risk of dysglycemia, which can be influenced by bacterial components and metabolites (i.e., postbiotics).
Angela M. Schmidt, Amee M. Scribe, Nicole G. Barra, Brittany M. Duggan, Han Fang, Dana Kukje Zada, Jonathan D. Schertzer   +6 more
wiley   +1 more source

Fatty acid synthesis is indispensable for Kupffer cells to eliminate bacteria in ALD progression. [PDF]

Hepatol Commun
Xie L, Wu B, Fan Y, Tao Y, Jiang X, Li Q, Zhu H, Wang H, Hu C.   +8 more
europepmc   +1 more source

Safety of nonapeptide–pentapeptide mixture as a novel food pursuant to regulation (EU) 2015/2283

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on a nonapeptide–pentapeptide mixture as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is a mixture composed of a 1:1 combination of nonapeptide and pentapeptide.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Thomas Frenzel, Francesca Marcon, Harry J. McArdle, Peter Moldeus, Monika Neuhäuser‐Berthold, Alexandros Siskos, Marcello Laganaro, Irene Nuin Garciarena, Francesco Suriano, Areti Favata, Anna‐Maria Pieger, Francesca Seminati, Karen Ildico Hirsch‐Ernst   +28 more
wiley   +1 more source

TMEM16F Expressed in Kupffer Cells Regulates Liver Inflammation and Metabolism to Protect Against Listeria Monocytogenes. [PDF]

Adv Sci (Weinh)
Tang J, Song H, Li S, Lam SM, Ping J, Yang M, Li N, Chang T, Yu Z, Liu W, Lu Y, Zhu M, Tang Z, Liu Z, Guo YR, Shui G, Veillette A, Zeng Z, Wu N.   +18 more
europepmc   +1 more source

Purification and Transcriptomic Characterization of Hypertrophied Hepatic Stellate Cells From CDAHFD Mouse Liver

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
The purification protocol for hypertrophied hepatic stellate cells (hypHSCs) developed in this study, using fibrotic and steatotic mouse livers (CDAHFD model), made it possible to obtain a high‐purity hypHSC preparation for transcriptomic analysis.
Marion Heckmann, Nour‐El‐Houda Djerir, Keola Greliche, Pierre‐Henri Commere, Julien Fernandes, Guillaume Sarrabayrouse, Bernard Hainque, Pascal Bigey, Virginie Escriou, Céline Hoffmann   +9 more
wiley   +1 more source

Kupffer cells dictate hepatic responses to the atherogenic dyslipidemic insult. [PDF]

Nat Cardiovasc Res
Di Nunzio G, Hellberg S, Zhang Y, Ahmed O, Wang J, Zhang X, Björck HM, Chizh V, Schipper R, Aulin H, Francis R, Fagerberg L, Gisterå A, Metso J, Manfé V, Franco-Cereceda A, Eriksson P, Jauhiainen M, Hagberg CE, Olofsson PS, Malin SG.   +20 more
europepmc   +1 more source

Human α2‐Macroglobulin: Architecture, Mechanisms, and Functional Implications

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Visual representation of human α2‐macroglobulin in its native and induced conformations. General functions associated with the native form (green), the induced form (white), and both conformations (light red) are indicated. ABSTRACT α2‐Macroglobulin (α2M) is a large glycoprotein and one of the most abundant proteins found in the plasma of vertebrates ...
Pietro de Carvalho Andrade, Tales Alexandre Costa‐Silva, Gisele Monteiro   +2 more
wiley   +1 more source

Author Correction: Hyaluronic acid 35 normalizes TLR4 signaling in Kupffer cells from ethanol-fed rats via regulation of microRNA291b and its target Tollip. [PDF]

Sci Rep
Saikia P, Roychowdhury S, Bellos D, Pollard KA, McMullen MR, McCullough RL, McCullough AJ, Gholam P, de la Motte C, Nagy LE.   +9 more
europepmc   +1 more source