Results 41 to 50 of about 50,401 (271)
Frontiers in Cell and Developmental Biology, 2021 Here, we studied the metabolic function of LAMTOR1 from macrophages using LAMTOR1 macrophage-specific knockout (MKO) mice. LAMTOR1 MKO mice showed resistance to high-fat diet (HFD)-induced obesity, lipid steatosis, and glucose metabolic disorders, with ...
Lingwen Ying +8 more
doaj +1 more source
Kupffer cells and alcoholic liver disease
, 2006 Department of Medicine. Division of Liver Diseases. Mount Sinai School of Medicine. New York, USALiver disease is a major cause of illness and death worldwide.
Nieto, Natalia +1 more
core +1 more source
Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expression
, 2007 Hepcidin, a small cationic liver derived peptide, is a master regulator of body iron homeostasis. Cytokines and iron availability have so far been identified as regulators of hepcidin expression.
Hochegger, Kathrin +16 more
core +1 more source
Cell Transplantation, 2013 Numerous approaches to cell transplantation of the hepatic or the extrahepatic origin into liver tissue have been developed; however, the efficiency of cell transplantation remains low and liver functions are not well corrected.
Il-Hwa Hong +11 more
doaj +1 more source
Life Science Alliance, 2018 This study reports on the identification of two Plasmodium GAPDH epitope peptides that are responsible for sporozoite–Kupffer cell interaction and act as antigens against malaria infection.
Sung-Jae Cha +2 more
doaj +1 more source
, 2014 (A) Scoring for the size and foamy appearance of Kupffer cells using CD68 staining. (B) Scoring for the size and foamy appearance of Kupffer cells using HE staining. A score ranging from 0–3 was given by an experienced pathologist.
Veerle Bieghs (186620) +15 more
core +1 more source
Advanced Materials, EarlyView.Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou +5 more
wiley +1 more source
iScience, 2021 Summary: Nonalcoholic fatty liver disease (NAFLD) is a global health-care problem with limited therapeutic options. To obtain a cellular resolution of pathogenesis, 82,168 single-cell transcriptomes (scRNA-seq) across different NAFLD stages were profiled,
Qi Su +12 more
doaj +1 more source
Minimally Invasive Delivery of Optical Nanosensors Using Injectable Hydrogels
Advanced Materials Interfaces, EarlyView.Injectable peptide hydrogels offer a minimally invasive delivery platform for single‐walled carbon nanotube (SWCNT)‐based near‐infrared fluorescent sensors, enabling real‐time measurement of drug concentrations. Encapsulated SWCNTs show a dose‐dependent fluorescence response across physiologically relevant concentrations and retain their fluorescence ...
Shirel Kleiner, Gili Bisker
wiley +1 more source
Angewandte Chemie, EarlyView.We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu +18 more
wiley +2 more sources