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A Calmodulin C-Lobe Ca2+-Dependent Switch Governs Kv7 Channel Function [PDF]

open access: yesNeuron, 2018
Kv7 (KCNQ) voltage-gated potassium channels control excitability in the brain, heart, and ear. Calmodulin (CaM) is crucial for Kv7 function, but how this calcium sensor affects activity has remained unclear.
Daniel L Minor   +2 more
exaly   +2 more sources
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Hormonal Signaling Actions on Kv7.1 (KCNQ1) Channels

Annual Review of Pharmacology and Toxicology, 2021
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Synthesis and Optimization of Kv7 (KCNQ) Potassium Channel Agonists: The Role of Fluorines in Potency and Selectivity

ACS Medicinal Chemistry Letters, 2019
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The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels

Neuropharmacology, 2006
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Regulation of Kv7.2/Kv7.3 channels by cholesterol: Relevance of an optimum plasma membrane cholesterol content

Biochimica Et Biophysica Acta - Biomembranes, 2018
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Modulation of Kv7 channels and excitability in the brain

Cellular and Molecular Life Sciences, 2016
Naoto Hoshi
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Peripheral KV7 channels regulate visceral sensory function in mouse and human colon

Molecular Pain, 2017
David C Bulmer   +2 more
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G-protein βγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity

Proceedings of the National Academy of Sciences of the United States of America, 2015
Vincenzo Barrese   +2 more
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