Results 251 to 260 of about 34,492 (275)

Use of Caenorhabditis elegans to Unravel the Tripartite Interaction of Kynurenine Pathway, UPR^mt and Microbiome in Parkinson's Disease. [PDF]

Biomolecules
Viau C, Nouar A, Xia J.
europepmc   +1 more source

SLC7A5 regulates tryptophan uptake and PD‑L1 expression levels via the kynurenine pathway in ovarian cancer. [PDF]

Oncol Lett
Jiang R, Jin B, Sun Y, Chen Z, Wan D, Feng J, Ying L, Peng C, Gu L.   +8 more
europepmc   +1 more source

Recombinant Protein Spectral Library (rPSL) DIA-MS method improves identification and quantification of low-abundance cancer-associated and kynurenine pathway proteins. [PDF]

Commun Chem
Krishnamurthy S, Gunasegaran B, Paul-Heng M, Mohamedali A, P Klare W, Pang CNI, Gluch L, Shin JS, Chan C, Baker MS, Ahn SB, Heng B.   +11 more
europepmc   +1 more source

Activated kynurenine pathway metabolism by YKL-40 establishes an inhibitory immune microenvironment and drives glioblastoma development. [PDF]

Cell Mol Life Sci
Chen H, Zhang X, Wang Z, Luo J, Liu Y, Shao R.   +5 more
europepmc   +1 more source

Memantine and the Kynurenine Pathway in the Brain: Selective Targeting of Kynurenic Acid in the Rat Cerebral Cortex. [PDF]

Cells
Kloc R, Urbanska EM.
europepmc   +1 more source

The kynurenine pathway in patients with rheumatoid arthritis during tumor necrosis factor α inhibitors treatment. [PDF]

Reumatologia
Witoszyńska-Sobkowiak J, Sikorska D, Niklas K, Żychowska I, Rutkowski R, Samborski W.   +5 more
europepmc   +1 more source

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Pharmacology of the kynurenine pathway

International Congress Series, 2007
Abstract The kynurenine pathway of tryptophan oxidative metabolism plays a major role in the nervous and immune systems and has been implicated in a range of disease states. Much of the interest in the pathway has been centred around the role of quinolinic acid as an agonist at glutamate receptors sensitive to N -methyl- d -aspartate (NMDA) and ...
Trevor W. Stone, L. Gail Darlington
openaire   +2 more sources

ChemInform Abstract: Inhibitors of the Kynurenine Pathway

ChemInform, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
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Kynurenine Pathway and Disease: An Overview

CNS & Neurological Disorders - Drug Targets, 2007
Kynurenine pathway is gaining more and more attention every day in biomedical research since this catabolic route for tryptophan decomposition is not only implicated in different neurological disorders, but also possesses neuroactive metabolites with different biological properties, such as pro-oxidant and antioxidant regulators.
Abel Santamaría, Mina Königsberg, Verónica Pérez de la Cruz   +2 more
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Kynurenine Pathway Enzymes in Guinea pigs [PDF]

, 2003
In some animals, the administration of repeated doses of tryptophan can cause death. It has been reported that guinea pig does not survive repeated doses of tryptophan, due to the absence of the hormonal induction mechanism of liver tryptophan 2,3-dioxygenase (TDO).
ALLEGRI, GRAZIELLA, COSTA, CARLO VIRGILIO LUIGI, RAGAZZI, EUGENIO, BERTAZZO, ANTONELLA, BIASIOLO M.   +4 more
openaire   +3 more sources