Results 41 to 50 of about 903,998 (248)

Ultrafast sub-nanometer matter-wave temporal Talbot effect

open access: yesNew Journal of Physics, 2021
The coherent manipulation of the electron wavefunction at the atomic spatial and temporal scales is the fundamental breakthrough underlying far-reaching ultrafast phenomena as high-order harmonic radiation and attosecond pulse generation.
Ana García-Cabrera   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

MODELO DE LA DESCARGA ELÉCTRICA QUE EXCITA A UN LÁSER PULSADO DE HF EN RÉGIMEN MULTILÍNEA

open access: yesAnales (Asociación Física Argentina), 2013
Mediante un modelo de la descarga eléctrica transversal, se reproduce el pulso obtenido con un láser de HF, iniciado con una mezcla de SF6/C3H8.
M. T. Bernal   +4 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

ESTUDIO DE UN SISTEMA LÁSER HÍBRIDO DE ITERBIO (Yb+3) Y TIPO RAMAN [PDF]

open access: yes, 2016
"El objetivo principal de este trabajo experimental es hacer más eficiente un láser de fibra óptica de tipo Raman bombeado con una señal láser a 1064 nm.
Oscar Javier Ballesteros Llanos
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Desarrollo de combustibles sólidos para propulsión láser [PDF]

open access: yes, 2023
En estos últimos años la propulsión láser ha ganado la atención de los grupos de investigación de propulsión alrededor del mundo. En primer lugar, h an emergido los sistemas láser con media y ultra-alta energía que encontraron su aplicación en la ...
Rinaldi, Carlos   +7 more
core  

Espectroscopia láser en nitrógeno molecular [PDF]

open access: yes, 2015
En este trabajo se intenta resumir la labor desarrollada en láseres gaseosos de excitación pulsada, particularmente en lo que respecta a láseres de nitrógeno molecular de geometría axial.
Scaffardi, Lucía Beatriz
core   +3 more sources

EXCITACIÓN DE UN LÁSER DE CO2 MEDIANTE MICROONDAS

open access: yesAnales (Asociación Física Argentina), 2013
Mediante un magnetrón de uso comercial operado en forma continua se excita una mezcla láser de CO2 confinada en una guía rectangular de 15 mm por 282 mm de sección, acoplada a la guía rectangular principal mediante dos bocinas; la primera del tipo ...
I. J. Ríos   +5 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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