Results 1 to 10 of about 18,029 (193)

Epistatic Interactions in the Arabinose Cis-Regulatory Element [PDF]

, 2016
Changes in gene expression are an important mode of evolution; however, the proximate mechanism of these changes is poorly understood. In particular, little is known about the effects of mutations within cis binding sites for transcription factors, or ...
Bollback, Jonathan P, Guet, Calin C, Igler, Claudia, Lagator, Mato, Moreno, Anaisa B   +4 more
core   +2 more sources

MutS regulates access of the error-prone DNA polymerase Pol IV to replication sites: a novel mechanism for maintaining replication fidelity [PDF]

, 2016
Translesion DNA polymerases (Pol) function in the bypass of template lesions to relieve stalled replication forks but also display potentially deleterious mutagenic phenotypes that contribute to antibiotic resistance in bacteria and lead to human disease.
Argaraña, Carlos Enrique, Fernández, Marisa Mariel, Malchiodi, Emilio Luis, Margara, Lucía, Monti, Mariela Roxana   +4 more
core   +1 more source

Disulfiram Enhances the Activity of Polymyxin B Against Klebsiella pneumoniae by Inhibiting Lipid A Modification

Infection and Drug Resistance, 2022
Wei Huang,1,2,* Jinyong Zhang,3,* Shiyi Liu,1 Chunxia Hu,1 Min Zhang,1 Shumin Cheng,1 Huijuan Yu,1,2 Manling Zheng,1 Jinsong Wu,2 Yuemei Lu,2 Quanming Zou,3 Ruiqin Cui1 1Bacteriology & Antibacterial Resistance Surveillance Laboratory, Shenzhen ...
Huang W, Zhang J, Liu S, Hu C, Zhang M, Cheng S, Yu H, Zheng M, Wu J, Lu Y, Zou Q, Cui R   +11 more
doaj  

A Serratia marcescens PigP Homolog Controls Prodigiosin Biosynthesis, Swarming Motility and Hemolysis and Is Regulated by cAMP-CRP and HexS [PDF]

, 2013
Swarming motility and hemolysis are virulence-associated determinants for a wide array of pathogenic bacteria. The broad host-range opportunistic pathogen Serratia marcescens produces serratamolide, a small cyclic amino-lipid, that promotes swarming ...
Arena, KE, Brothers, KM, Kalivoda, EJ, Kwak, DH, Lahr, RM, Liu, X, Shanks, RMQ, Stella, NA   +7 more
core   +1 more source

Galactose Metabolism Plays a Crucial Role in Biofilm Formation by Bacillus subtilis [PDF]

, 2014
Galactose is a common monosaccharide that can be utilized by all living organisms via the activities of three main enzymes that make up the Leloir pathway: GalK, GalT, and GalE.
Beauregard, Pascale, Chai, Yunrong, Kolter, Roberto Guillermo, Losick, Richard M., Vlamakis, Hera C   +4 more
core   +1 more source

Optimizing Systems for Robust Heterologous Production of Biosurfactants Rhamnolipid and Lyso-Ornithine Lipid in Pseudomonas putida KT2440

Molecules
Surfactants are amphiphilic molecules that are capable of mixing water and oil. Biosurfactants are eco-friendly, low-toxicity, and stable to a variety of environmental factors.
Xuelian Li, Zhili Yang, Jianhua Liu
doaj   +1 more source

Phenotypic Variation and Bistable Switching in Bacteria [PDF]

, 2008
Microbial research generally focuses on clonal populations. However, bacterial cells with identical genotypes frequently display different phenotypes under identical conditions.
A Becskei, A Becskei, A Guerrero, A Johnson, A Khlebnikov, A Khlebnikov, A Khlebnikov, A Lipshtat, A Moter, A Novick, AE Merode van, AE Merode van, AE Tsong, B Muller-Hill, B Slutsky, BB Magee, BE Laue, BF Brehm-Stecher, BJ Haijema, C Hadden, C Wiuff, CM Hull, CM Hull, CM Southward, CY Lan, D Angeli, D Dubnau, D Dubnau, D Dubnau, D Kidane, D Sinderen van, D Sinderen van, DB Kearns, DC Dooley, DH Dean, DR Soll, E Korobkova, E Kussell, EH Rikkerink, EJ Stewart, EM Ozbudak, EM Ozbudak, ER Sumner, EW Nester, F Jacob, F Joux, F Ortega, F Russo-Marie, FH Cahn, FH Kasten, FJ Isaacs, G Huang, G Nebe-von-Caron, GM Suel, GM Suel, H Kobayashi, H Maamar, H Makinoshima, H Steinmoen, H Steinmoen, HB Fraser, HM Davey, I Golding, I Golding, I Hautefort, IR Henderson, J Casadesus, J Hahn, J Hahn, J Hasty, J Hasty, J Holtzendorff, J Kreth, J Monod, J Vidal-Mas, J Vives-Rego, J Zieg, JD Chung, JD Chung, JD Chung, JE Ferrell Jr, JE Ferrell Jr, JE Gonzalez-Pastor, JE Lisman, JM Abraham, JM Anderson, JM Pedraza, JR Glynn Jr, JW Veening, K Lewis, KA Susanna, KP Lemon, KZ Abshire, L Cai, LF Greer III, LW Hamoen, LW Hamoen, M Acar, M Albano, M Albano, M Albano, M Cohn, M Cohn, M Lange, M Laurent, M Leisner, M Santillán, M Thattai, M Woude van der, MB Elowitz, MB Elowitz, MG Miller, MJ Hoek van, MR Barer, N Chantratita, N Friedman, N Rosenfeld, N Yildirim, N Yildirim, NC Shaner, NC Shaner, NE Kramer, NQ Balaban, P Viswanathan, PS Swain, R Amann, R Carballido-Lopez, R Thomas, R Thomas, RA Daniel, RE Zordan, RI Amann, RJ Bennett, RM Morgan-Kiss, RN Singh, RN Singh, RP Burchard, RP Haugland, RY Tsien, S Guiral, S Hooshangi, S Stibitz, SB Williams, SE Finkel, SR Biggar, SR Lockhart, SR Lockhart, SV Avery, T Hornbaek, T Nishino, T Tian, T Tolker-Nielsen, TF Meyer, TS Gardner, TT Hoa, V Sentchilo, V Sentchilo, WK Smits, WK Smits, WK Smits   +159 more
core   +3 more sources

Levilactobacillus brevis 47f: Bioadaptation to Low Doses of Xenobiotics in Aquaculture

Biology
Agricultural and industrial activities are increasing pollution of water bodies with low doses of xenobiotics that have detrimental effects on aquaculture.
Diana Reznikova, Nikita Kochetkov, Alexey Vatlin, Dmitry Nikiforov-Nikishin, Olesya Galanova, Anastasia Klimuk, Svetlana Smorodinskaya, Daria Matyushkina, Alexey Kovalenko, Ivan Butenko, Maria Marsova, Valery Danilenko   +11 more
doaj   +1 more source

Development of novel orthogonal genetic circuits, based on extracytoplasmic function (ECF) σ factors [PDF]

, 2019
The synthetic biology field aims to apply the engineering 'design-build-test-learn' cycle for the implementation of synthetic genetic circuits modifying the behavior of biological systems. In order to reach this goal, synthetic biology projects use a set
Vecchione, Stefano
core   +1 more source

Phenotypic microarrays suggest Escherichia coli ST131 is not a metabolically distinct lineage of extra-intestinal pathogenic E. coli [PDF]

, 2014
Extraintestinal pathogenic E. coli (ExPEC) are the major aetiological agent of urinary tract infections (UTIs) in humans. The emergence of the CTX-M producing clone E. coli ST131 represents a major challenge to public health worldwide.
A Coelho, A Cove-Smith, A McNally, A McNally, Abdulaziz Alqasim, Alan McNally, AR Pacheco, AT Anfora, B Foxman, B Foxman, BR Bochner, C Le Bouguénec, DM Livermore, F Alhashash, G Clark, G Croxall, G Croxall, G Peirano, Gemma Clark, Jane Newcombe, JDD Pitout, JL Smith, JR Johnson, JR Johnson, L Rohmer, L Zhang, LM Durso, M Akram, MH Nicolas-Chanoine, MS Litwin, N Woodford, Niyaz Ahmed, O Clermont, OR Homann, R Welch, Richard Emes, Roberto La Ragione, S Farajnia, SH Lau, SH Lau, SK Sheppard, SL Chen, TJ Carver, TM Gibreel, TM Gibreel, V Leflon-Guibout, V Pancholi   +46 more
core   +6 more sources