Isolation of specialized transducing bacteriophage lambda carrying genes of the L-arabinose operon of Escherichia coli B/r [PDF]
Journal of Bacteriology, 1975 A heat-inducible lysis-defective phage lambda (lambdacI857S7) has been integrated at multiple sites within the L-arabinose region (araCOIBAD) of a strain of Escherichia coli K-12 deleted for the normal lambda attachment site (lambdaattdelta). The lambda phage has become integrated with opposite orientations at two different loci within the aratb gene ...
James Boulter, N Lee
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Metabolite gene regulation: imidazole and imidazole derivatives which circumvent cyclic adenosine 3',5'-monophosphate in induction of the Escherichia coli L-arabinose operon [PDF]
Journal of Bacteriology, 1980 Imidazole, histidine, histamine, histidinol phosphate, urocanic acid, or imidazolepropionic acid were shown to induce the L-arabinose operon in the absence of cyclic adenosine 3',5'-monophosphate. Induction was quantitated by measuring the increased differential rate of synthesis of L-arabinose isomerase in Escherichia coli strains which carried a ...
Ellis L. Kline +3 more
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AraC protein, regulation of the l-arabinose operon inEscherichia coli, and the light switch mechanism of AraC action [PDF]
FEMS Microbiology Reviews, 2010 This review covers the physiological aspects of regulation of the arabinose operon in Escherichia coli and the physical and regulatory properties of the operon's controlling gene, araC. It also describes the light switch mechanism as an explanation for many of the protein's properties. Although many thousands of homologs of AraC exist and regulate many
Robert Schleif
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Novel Mutation to Dominant Fucose Resistance in the
Journal of Bacteriology, 1973 We isolated an unusual mutant in which the arabinose operon carried an araC lesion that led to a dominant fucose resistance while retaining recessive constitutivity. All previously characterized C c mutations have been recessive for both fucose resistance and constitutivity.
Neil M. Nathanson, Robert Schleif
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Dominance relationships among mutant alleles of regulatory gene araC in the Escherichia coli B/R L-arabinose operon [PDF]
Journal of Bacteriology, 1986 The araBAD operon of Escherichia coli B/r is positively and negatively regulated by the araC+ regulatory protein. Mutations in gene araC can result in a variety of different regulatory phenotypes: araC null mutants (those carrying a null allele exhibiting no repressor or activator activity) are unable to achieve operon induction; araC-constitutive ...
David E. Sheppard
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Hypersensitivity to Catabolite Repression in the
Journal of Bacteriology, 1976 Mutations causing hypersensitivity to catabolite repression have been assigned to gene araC (activator protein) by complementation analysis. The araO (operator region) is non-essential for catabolite repression.
David E. Sheppard, Marianne Eleuterio
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Deoxyribonucleic Acid-Ribonucleic Acid Hybridization Studies on the
Journal of Bacteriology, 1971 An increase in the rate of synthesis of ara -specific messenger ribonucleic acid as measured by deoxyribonucleic acid-ribonucleic acid hybridization has been detected in the induced wild-type ( ara + ) strain of Escherichia coli B/r as compared with the ...
Gary Wilcox +2 more
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Targeted deletion of thearaoperon ofSalmonella typhimuriumenhances L-arabinose accumulation and drives PBAD-promoted expression of anti-cancer toxins and imaging agents [PDF]
Cell Cycle, 2014 Tumor-specific expression of antitumor drugs can be achieved using attenuated Salmonella typhimurium harboring the PBAD promoter, which is induced by L-arabinose. However, L-arabinose does not accumulate because it is metabolized to D-xylulose-5-P by enzymes encoded by the ara operon in Salmonellae.
Hyun Hee Hong +7 more
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Using Cellular Automata and Global Sensitivity Analysis to Study the Regulatory Network of the L-Arabinose Operon [PDF]
, 2013 The field of computational biologyhas grown significantly in recent years, allowing re‐ searchers to investigatecomplex biological systems in silico. In this chapter, a new method of combining cellular automata (CA) with global sensitivity analysis (GSA) is introduced.
A. Advait +2 more
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Journal of Bacteriology, 1971 d -Fucose, a nonmetabolizable analogue of l -arabinose, prevents growth of Escherichia coli B/r on a mineral salts medium plus l -arabinose by inhibiting induction of the l -arabinose operon. Mutations giving rise to d
Susan Beverin +2 more
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