Results 31 to 40 of about 18,029 (193)

What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems [PDF]

, 2014
Multistable gene regulatory systems sustain different levels of gene expression under identical external conditions. Such multistability is used to encode phenotypic states in processes including nutrient uptake and persistence in bacteria, fate ...
Berg, Johannes, Bhogale, Prasanna M., Sorg, Robin A., Veening, Jan-Willem   +3 more
core   +2 more sources

The Role of the [2Fe-2S] Cluster of Escherichia coli IscR in Responding to Redox-Cycling Agents. [PDF]

Mol Microbiol
Redox cycling agents like phenazine methosulfate (PMS) are known for upsetting cellular redox balance. Here we describe how PMS leads to upregulation of the ISC and SUF Fe‐S cluster biogenesis pathways in Escherichia coli when PMS oxidizes the [2Fe‐2S]1+ cluster of the transcription factor IscR, thereby derepressing the operon encoding ISC and, when a ...
Banerjee R, Mettert EL, Fleischhacker AS, Kiley PJ.   +3 more
europepmc   +2 more sources

Pleiotropic functions of catabolite control protein CcpA in Butanol-producing Clostridium acetobutylicum

BMC Genomics, 2012
Background Clostridium acetobutylicum has been used to produce butanol in industry. Catabolite control protein A (CcpA), known to mediate carbon catabolite repression (CCR) in low GC gram-positive bacteria, has been identified and characterized in C ...
Ren Cong, Gu Yang, Wu Yan, Zhang Weiwen, Yang Chen, Yang Sheng, Jiang Weihong   +6 more
doaj   +1 more source

Enhancing gold recovery from electronic waste via lixiviant metabolic engineering in Chromobacterium violaceum [PDF]

, 2013
10.1038/srep02236Scientific ...
A Treumann, C Hagelüken, CJ Knowles, DA Miller, DE Rawlings, F Korte, G Liang, GW Ashley, H Brandl, HT Tan, J Cui, J Laville, JEA Zlosnik, JF Mead, K Hiraga, KC Agarwal, KH Choi, KH Choi, L Valenzuela, MA Faramarzi, MS Carepo, O Tsydenova, PG Sadowski, R Michaels, R Michaels, S Fields, S Ilyas, SC Campbell, SL Camhi, T Yoshida, V Pham, W Krebs, Y Kita, Y Motokawa, Y Xiang   +34 more
core   +1 more source

Functional Characterization and Evolution of the Isotuberculosinol Operon in Mycobacterium Tuberculosis and Related Mycobacteria [PDF]

, 2012
Terpenoid metabolites are important to the cellular function, structural integrity, and pathogenesis of the human-specific pathogen Mycobacterium tuberculosis (Mtb).
Davenport, Emily, Mann, Francis, Peters, Reuben, Peters, Reuben, Xu, Meimei   +4 more
core   +4 more sources

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

The consequences of replicating in the wrong orientation: Bacterial chromosome duplication without an active replication origin [PDF]

, 2015
Chromosome replication is regulated in all organisms at the assembly stage of the replication machinery at specific origins. In Escherichia coli the DnaA initiator protein regulates the assembly of replication forks at oriC.
Dimude, JU, Foster, HA, Khan, A, Midgley-Smith, SL, Retkute, R, Rudolph, CJ, Saunders, NJ, Stockum, A, Upton, AL   +8 more
core   +1 more source

Expanding the Toolbox for Inducible Protein Expression With Automation‐enabled Generation of Glycomimetics

Chemistry – A European Journal, EarlyView.
Inducible protein expression is a cornerstone of many aspects of industrial and molecular biotechnological processes. 2′‐fucosyl isopropyl‐β‐D‐thiogalactopyranose (2′F‐IPTG) and 2′‐fucosyl isobutyl‐C‐galactoside (2′F‐IBCG) mimics were explored for protein expression studies.
Ashley E. DeYong, Keevan C. Marion, Murat Ozturk, Sanjeeva Kumar Murali, Fatima Enam, Thomas J. Mansell, Nicola L. B. Pohl   +6 more
wiley   +1 more source

The Prebiotic and Techno‐Functional Potential of Microbial Exopolysaccharides for Human Health and Food Systems

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 2, March 2026.
ABSTRACT Microbial exopolysaccharides (EPS) represent a diverse class of biopolymers holding considerable promise as functional food ingredients. This review analyzes the dual function of microbial EPS as a candidate for prebiotic agents and techno‐functional additives.
Md. Abdur Razzak, Hye Kim, Md. Ariful Haque, Min Ji Jang, Sehyeon Song, Anishka Talari, Lakshmi Devi Chittepu, Seockmo Ku   +7 more
wiley   +1 more source

SbcCD regulation and localization in Escherichia coli [PDF]

, 2007
The SbcCD complex and its homologues play important roles in DNA repair and in the maintenance of genome stability. In Escherichia coli, the in vitro functions of SbcCD have been well characterized, but its exact cellular role remains elusive.
Borking, Amanda, Darmon, Elise, Helness, Anne C, Leach, David R F, Lopez-Vernaza, Manuel A, Thacker, Zubin, Wardrope, Laura, Wilson, Emily   +7 more
core   +2 more sources