Results 41 to 50 of about 8,929 (131)

The Quorum Sensing Regulated sRNA Lrs1 Is Involved in the Adaptation to Low Iron in Pseudomonas aeruginosa. [PDF]

Environ Microbiol Rep
The quorum sensing regulated sRNA Lrs1 participates in the adaptation of Pseudomonas aeruginosa in low iron by downregulating the siderophore pyochelin, the Quorum Sensing system PQS, and its associated virulence factor phenazines. ABSTRACT Iron is an essential nutrient for microbial growth. The opportunistic pathogen Pseudomonas aeruginosa can survive
Panagiotopoulou D, Catalán NR, Wilcox M, Halliday N, Pantalone P, Lazenby J, Cámara M, Heeb S.   +7 more
europepmc   +2 more sources

Comparative Metabolomics and Transcriptomics Reveal Multiple Pathways Associated with Polymyxin Killing in Pseudomonas aeruginosa

mSystems, 2019
Polymyxins are a last-line therapy against multidrug-resistant Pseudomonas aeruginosa; however, resistance to polymyxins has been increasingly reported.
Mei-Ling Han, Yan Zhu, Darren J. Creek, Yu-Wei Lin, Alina D. Gutu, Paul Hertzog, Tony Purcell, Hsin-Hui Shen, Samuel M. Moskowitz, Tony Velkov, Jian Li   +10 more
doaj   +3 more sources

Pleiotropic functions of catabolite control protein CcpA in Butanol-producing Clostridium acetobutylicum

BMC Genomics, 2012
Background Clostridium acetobutylicum has been used to produce butanol in industry. Catabolite control protein A (CcpA), known to mediate carbon catabolite repression (CCR) in low GC gram-positive bacteria, has been identified and characterized in C ...
Ren Cong, Gu Yang, Wu Yan, Zhang Weiwen, Yang Chen, Yang Sheng, Jiang Weihong   +6 more
doaj   +1 more source

Dynamic and single cell characterization of a CRISPR-interference toolset in Pseudomonas putida KT2440 for β-ketoadipate production from p-coumarate

Metabolic Engineering Communications, 2022
Pseudomonas putida KT2440 is a well-studied bacterium for the conversion of lignin-derived aromatic compounds to bioproducts. The development of advanced genetic tools in P.
Jacob A. Fenster, Allison Z. Werner, Jian Wei Tay, Matthew Gillen, Leo Schirokauer, Nicholas C. Hill, Audrey Watson, Kelsey J. Ramirez, Christopher W. Johnson, Gregg T. Beckham, Jeffrey C. Cameron, Carrie A. Eckert   +11 more
doaj  

Disulfiram Enhances the Activity of Polymyxin B Against Klebsiella pneumoniae by Inhibiting Lipid A Modification

Infection and Drug Resistance, 2022
Wei Huang,1,2,* Jinyong Zhang,3,* Shiyi Liu,1 Chunxia Hu,1 Min Zhang,1 Shumin Cheng,1 Huijuan Yu,1,2 Manling Zheng,1 Jinsong Wu,2 Yuemei Lu,2 Quanming Zou,3 Ruiqin Cui1 1Bacteriology & Antibacterial Resistance Surveillance Laboratory, Shenzhen ...
Huang W, Zhang J, Liu S, Hu C, Zhang M, Cheng S, Yu H, Zheng M, Wu J, Lu Y, Zou Q, Cui R   +11 more
doaj  

Optimizing Systems for Robust Heterologous Production of Biosurfactants Rhamnolipid and Lyso-Ornithine Lipid in Pseudomonas putida KT2440

Molecules
Surfactants are amphiphilic molecules that are capable of mixing water and oil. Biosurfactants are eco-friendly, low-toxicity, and stable to a variety of environmental factors.
Xuelian Li, Zhili Yang, Jianhua Liu
doaj   +1 more source

Levilactobacillus brevis 47f: Bioadaptation to Low Doses of Xenobiotics in Aquaculture

Biology
Agricultural and industrial activities are increasing pollution of water bodies with low doses of xenobiotics that have detrimental effects on aquaculture.
Diana Reznikova, Nikita Kochetkov, Alexey Vatlin, Dmitry Nikiforov-Nikishin, Olesya Galanova, Anastasia Klimuk, Svetlana Smorodinskaya, Daria Matyushkina, Alexey Kovalenko, Ivan Butenko, Maria Marsova, Valery Danilenko   +11 more
doaj   +1 more source

Bacterial Minicell‐Based Biohybrid Sub‐micron Swimmers for Targeted Cargo Delivery

Advanced Science, EarlyView.
Bacterial minicells, vesicles derived from engineered E. coli, offer promising sub‐micron scale biohybrid swimmers for targeted cargo delivery. Purified with over 99% efficiency while retaining motility, they are functionalized with MNPs for controlled movement.
Saadet Fatma Baltaci, Mukrime Birgul Akolpoglu, Irina Kalita, Victor Sourjik, Metin Sitti   +4 more
wiley   +1 more source

Investigation on Klebsiella pneumoniae in the field of extracellular vesicles

Interdisciplinary Medicine, EarlyView.
The role of extracellular vesicles in the pathogenicity and antibiotic resistance, as well as treatment and prevention of Klebsiella pneumoniae. Abstract Klebsiella pneumoniae (KP), recognized for its pronounced antibiotic resistance, is a prevalent agent of nosocomial infections such as hospital‐acquired pneumonia.
Junwei Wu, Yuheng Liu, Jin Su, Yi Yang, Haiyi Deng, Yilin Yang, Mengxi Yanglan, Xinyi Wu, Shiqi Luo, Yao Liao, Lifu Wang   +10 more
wiley   +1 more source

DASH: a versatile and high‐capacity gene stacking system for plant synthetic biology

Plant Biotechnology Journal, EarlyView.
Summary DNA assembly systems based on the Golden Gate method are popular in synthetic biology but have several limitations: small insert size, incompatibility with other cloning platforms, DNA domestication requirement, generation of fusion scars, and lack of post‐assembly modification.
Chengsong Zhao, Anna N. Stepanova, Jose M. Alonso   +2 more
wiley   +1 more source