Results 61 to 70 of about 8,929 (131)

Cpx‐mediated amino acid sensing diversifies gastrointestinal colonization of Klebsiella pneumoniae

mLife, Volume 4, Issue 2, Page 181-192, April 2025.
Abstract Klebsiella pneumoniae is a Gram‐negative opportunistic pathogenic bacterium that occasionally inhabits the human gastrointestinal tracts. Gut‐colonized K. pneumoniae may then metastasize to other organs and tissues, thus causing severe infections. In this study, we identified three cpxA mutations in K. pneumoniae that experimentally evolved to
Danyang Li, Qiucheng Shi, Liuqing He, Jianhua Luo, Huajie Zhu, Xiaoting Hua, Yunsong Yu, Yan Jiang, Liang Tao   +8 more
wiley   +1 more source

Regulation of Sugar Metabolism During Fermentation of Brewers' Spent Grain by Leuconostoc pseudomesenteroides DSM20193

Microbial Biotechnology, Volume 18, Issue 4, April 2025.
This study reveals the regulatory mechanism behind sugar metabolism and dextran synthesis by Leuconostoc pseudomesenteroides DSM20193 during the fermentation of a complex substrate like brewers spent grain. Understanding metabolic pathways and genetic adaptation of lactic acid bacteria in food environments can help develop fermented products with ...
Koirala Prabin, Maina Ndegwa, Mojzita Dominik, Coda Rossana   +3 more
wiley   +1 more source

Genetic Dissection of Cyclic di‐GMP Signalling in Pseudomonas aeruginosa via Systematic Diguanylate Cyclase Disruption

Microbial Biotechnology, Volume 18, Issue 4, April 2025.
All 32 diguanylate cyclase (DGC)‐encoding genes of P. aeruginosa PA14 were interrupted by premature STOP codons, introduced through a multiplexed cytosine base‐editor. The synthesis of c‐di‐GMP was impaired in the resulting strain lacking all 32 DGCs (strain PA14Δ32). Phenotypic analysis confirmed major behaviour changes in P. aeruginosa PA14Δ32, which
Román A. Martino, Daniel C. Volke, Albano H. Tenaglia, Paula M. Tribelli, Pablo I. Nikel, Andrea M. Smania   +5 more
wiley   +1 more source

DNA Polymerase IV dinB Favors the Adaptive Fitness of mcr‐carrying Bacteria Through a Negative Feedback Regulatory Mechanism

Advanced Science, Volume 12, Issue 12, March 27, 2025.
This work demonstrates that DNA polymerase IV dinB favors the adaptive fitness of mcr‐carrying bacteria via a negative feedback regulatory mechanism. Specifically, the elevation of ROS production by intact mcr activates dinB, which in turn represses the mcr expression, maintaining a balance between colistin resistance and bacterial fitness.
Haijie Zhang, Xia Xiao, Chenlong Wang, Yurong Zhao, Bo Chen, Xinyuan Ji, Lina Gu, Jie Wang, Zhiqiang Wang, Yuan Liu   +9 more
wiley   +1 more source

Xylose Metabolism and Transport in <i>Bacillus subtilis</i> and Its Application to D-Ribose Production. [PDF]

J Microbiol Biotechnol
Park YC.
europepmc   +1 more source

Unsilencing a cryptic xylose metabolic pathway in Rhodococcus jostii RHA1 for efficient lipid production from lignocellulosic biomass. [PDF]

J Biol Eng
Acedos MG, De la Torre I, Barriuso J, García JL.   +3 more
europepmc   +1 more source

The two-component system CpxAR controls biofilm formation by directly regulating the T3SS needle tip protein EseB in <i>Edwardsiella piscicida</i>. [PDF]

Appl Environ Microbiol
Zhang SY, Sun SS, Liu LY, Sivaranjan T, Nie P, Xie HX.   +5 more
europepmc   +1 more source

The Genetic Background and Culture Medium Only Marginally Affect the In Vitro Evolution of <i>Pseudomonas aeruginosa</i> Toward Colistin Resistance. [PDF]

Antibiotics (Basel)
Cervoni M, Ferriero AM, Lo Sciuto A, Guidi F, Babić Jordamović N, Piazza S, Jousson O, Esposito A, Imperi F.   +8 more
europepmc   +1 more source

Genetic and structural insights into the functional importance of the conserved gly-met-rich C-terminal tails in bacterial chaperonins. [PDF]

Commun Biol
Kumar CMS, Mai AM, Mande SC, Lund PA.
europepmc   +1 more source

The small regulatory RNA DsrA silences the locus of enterocyte effacement of enteropathogenic <i>Escherichia coli</i> in an RpoS-dependent manner. [PDF]

MicroPubl Biol
Critelli B, Mrozek Z, Mihaita A, Long L, Robinson A, Bhatt S.   +5 more
europepmc   +1 more source