Results 141 to 150 of about 268,588 (307)

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

open access: yesAdvanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto   +6 more
wiley   +1 more source

BAHAN PENYERAP KMnO4 DAN ASAM L-ASKORBAT DALAM PENGEMASAN AKTIF (ACTIVE PACKAGING) UNTUK MEMPERPANJANG MASA SIMPAN DAN MEMPERTAHANKAN MUTU BUAH DUKU (Lansium domesticum Corr.) [Adsorbers for KMnO4 and L-Ascorbic Acid in the Active Packaging to Prolong the Shelve-Life and Maintain the Quality of Lanzone (Lansium domesticum Corr.) Fruits]

open access: yesJurnal Teknologi dan Industri Pangan, 2005
To develop an active packaging of lanzone (Lansium domisticum Corr.) Fruits, KmnO4 as an ethylene scavenger and L-ascorbic acid as an oxygent scavenger were inserted into packaging. As direct contact of KmnO4 with agricultural product was not recommended
Soesiladi E Widodo
doaj  

Graphene‐Interfaced Stretchable Sweat Patch for Multiplexed Electrochemical Monitoring of IL‐6, Glucose, and Calcium Ions

open access: yesAdvanced Materials Technologies, EarlyView.
Flexible sweat sensor patch integrating graphene‑interfaced gold microelectrodes functionalized with bio‑receptors and ion‑selective membrane, coupled with a capillary‑driven microfluidic layer and portable potentiostat electronics for multiplexed monitoring of inflammatory, metabolic, and electrolyte biomarkers in microliter sweat volumes.
Roomia Memon   +4 more
wiley   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He   +17 more
wiley   +1 more source

CHANGES OF DEHYDROASCORBIC ACID CONTENT IN RELATION TO TOTAL CONTENT OF VITAMIN C IN SELECTED FRUITS AND VEGETABLES

open access: yesActa Scientiarum Polonorum: Hortorum Cultus, 2012
Vitamin C performs many functions in the human body and is very important for its proper functioning. The main vitamin C sources in the human diet are fruits and vegetables.
Artur Mazurek, Urszula Pankiewicz
doaj  

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

open access: yesAdvanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao   +16 more
wiley   +1 more source

METABOLIC PRODUCTS OF l-ASCORBIC ACID

open access: yesJournal of Biological Chemistry, 1958
P C, CHAN, R R, BECKER, C G, KING
openaire   +2 more sources

Mass Spectrometry Imaging‐Assisted Discovery of Gallotannin Biosynthetic Genes in the Root of Paeonia suffruticosa

open access: yesAdvanced Science, EarlyView.
An integrated approach combining mass spectrometry imaging, transcriptomics, and phylogenetic analysis facilitated the efficient identification of genes involved in gallotannin biosynthesis in Paeonia suffruticosa. As a result, a key UGT and several SCPL acyltransferases responsible for biosynthesizing pentagalloylglucose were successfully identified ...
Yushi Liu   +4 more
wiley   +1 more source

Neurolathyrism and L-ascorbic Acid [PDF]

open access: yesFood and Nutrition Bulletin, 1982
Kamaluddin Ahmad, Khursheed Jahan
openaire   +1 more source

A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain

open access: yesAdvanced Science, EarlyView.
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang   +15 more
wiley   +1 more source

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