Results 181 to 190 of about 268,588 (307)

Senomorphic Small Extracellular Vesicles Delivered by a Tissue‐Adhesive α‐Lipoic‐Acid Hydrogel Enable Immuno‐Rejuvenation for Bone‐Tendon Interface Regeneration

Advanced Science, EarlyView.
This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong, Wei Song, Wencai Liu, Hui Xu, Yuhao Yu, Xinyue Yang, Haiyan Li, Yanlun Zhu, Yaohua He   +8 more
wiley   +1 more source

Valproic Acid Enhances the Anticancer Effect of L-Ascorbic Acid by Upregulating Sodium-Dependent Vitamin C Transporter 2 in Colorectal Cancer. [PDF]

Antioxidants (Basel)
Kantawong K, Diva HM, Ho PT, Lee A, Kiba M, Lee MG, Kang H, Lee TK, Lee S.   +8 more
europepmc   +1 more source

Improving adsorption performance of L-ascorbic acid from aqueous solution using magnetic rice husk as an adsorbent: experimental and RSM modeling. [PDF]

Sci Rep, 2023
Aslani A, Masoumi H, Ghanadzadeh Gilani H, Ghaemi A.   +3 more
europepmc   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

L-Ascorbic Acid (LAA) Supplementation as a Potential Treatment for Skin Aging: Regulation of Adipose Tissue Mesenchymal Stem Cells (AT-MSCs) Protein Secretion. [PDF]

Curr Issues Mol Biol
Wahyuningsih KA, Wiratnaya IGE, Weta IW, Widiana IGR, Pangkahila WI, Wahyuniari IAI, Muliarta IM, Sidharta VM, Salwa A.   +8 more
europepmc   +1 more source

One-Step Ultrasonic Preparation of Stable Bovine Serum Albumin-Perovskite for Fluorescence Analysis of L-Ascorbic Acid and Alkaline Phosphatase. [PDF]

Biosensors (Basel), 2023
Deng L, Huang F, Zhang A, Wang T, Yang M, Li X, Chen X.   +6 more
europepmc   +1 more source

Helicalization of Covalent Organic Framework Nanofibers with Amplified Spin Polarizability for Boosting Photocatalytic Hydrogen Evolution

Advanced Science, EarlyView.
A non‐covalent chirality‐induced strategy via chiral solvents is presented to synthesize helical 2D COF nanofibers with high crystallinity, high chirality, and high spin polarization. The helical structure enhances the concentration of photogenerated charges, suppresses exciton recombination, and extends carrier lifetimes, thereby significantly ...
Qi Zhong, Yongtu Tian, Yutao Sang, Changchun Wang, Jia Guo   +4 more
wiley   +1 more source

Grape seed extract and L-ascorbic acid exert antineoplastic effects against solid Ehrlich carcinoma <i>in vivo</i> by modulating the tumor microenvironment and Th1/Th2 balance. [PDF]

Front Immunol
Morsi DS, Hathout HMR, AboShabaan HS, Emam M, El-Khadragy M, Abdel Moneim AE, El-Garawani IM, Abu Quora HA.   +7 more
europepmc   +1 more source

Preparation, Characterization, and Antioxidant Activity of L-Ascorbic Acid/HP-β-Cyclodextrin Inclusion Complex-Incorporated Electrospun Nanofibers. [PDF]

Foods, 2023
Khan N, Singh AK, Saneja A.
europepmc   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source