Results 111 to 120 of about 22,972 (221)

Do immunoglobulin G and immunoglobulin E anti-l-asparaginase antibodies have distinct implications in children with acute lymphoblastic leukemia? A cross-sectional study

open access: yesRevista Brasileira de Hematologia e Hemoterapia
Background l-Asparaginase is essential in the treatment of childhood acute lymphoblastic leukemia. If immunoglobulin G anti-l-asparaginase antibodies develop, they can lead to faster plasma clearance and reduced efficiency as well as to hypersensitivity
Gabriela Galindo-Rodríguez   +8 more
doaj   +1 more source

Diverse origins of microbial L-asparaginases and their current miscellaneous applications

open access: yesArchives of Pharmaceutical Sciences Ain Shams University, 2019
L-asparaginase, also known as amidohydrolase, catalyzes the breakdown of asparagine into aspartic acid and ammonia. Due to its ability to inhibit the biosynthesis of protein lymphoblasts, it is used to treat acute lymphoblastic leukemia (ALL).
Nada A. Abdelrazek   +3 more
doaj   +1 more source

A Surface Acoustic Wave (SAW) biosensor method for functional quantification of E. coli l-asparaginase

open access: yes, 2019
Biosensors are rising technologies in the pharmaceutical field for medicine discovery, development and Quality Control (QC) stages. Surface acoustic wave (SAW) biosensor employs acoustic waves generated by oscillating a piezoelectric crystal quartz plate
De Spiegeleer, Bart   +4 more
core   +1 more source

Chemosensitizing effect of apigenin on T-ALL cell therapy

open access: yesFrontiers in Pharmacology
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy with limited therapeutic options and frequent treatment-associated toxicities.
Nigar Huseynova   +4 more
doaj   +1 more source

Results of chemotherapy by UKCCSG protocol in children with acute lymphoblastic leukemia: Clinical characteristics and outcome [PDF]

open access: yes
Background: Acute lymphoblastic leukemia (ALL) represents a clonal expansion and arrest of normal lymphoid hematopoiesis. ALL remains the most common malignancy in children.
فتحی, افشین   +2 more
core  

Recent progress on the development of nanoparticulate L-asparaginase for enhanced anti-cancer activity

open access: yesCancer Nanotechnology
Background L-Asparaginase is a medically important enzyme known to be a chemotherapeutic agent and is often used in multi-agent chemotherapeutic regimens.
Sahand Mazloum-Ravasan   +1 more
doaj   +1 more source

L-asparaginase-antileukemia agent.

open access: yesJPMA. The Journal of the Pakistan Medical Association, 1977
This paper is an extension of a previous report (Yaqub 1975). Our interest in L-asparaginase is increasing due to the recognition of the fact that it is a best tool against leukemia. In this paper we have tried to discuss (in view of research work, 1973-75) its basic characteristics and its practicability of successfully being used as an antitumour ...
A, Jabbar, M, Yaqub
openaire   +2 more sources

The lipid composition and its alteration during the growth stage in pathogenic fungus, epidermophyton floccosum [PDF]

open access: yes
Qualitative and quantitative changes of lipid components during the growth stages were studied in E. floccosum. The acyl group components of total lipids of Trichophyton rubrum and Microsporum cookei were also examined. The lipids of E.
Ito, Y.   +3 more
core   +1 more source

Isolation and optimization of Asparaginase producing bacteria in solid state fermentation by Plackett-Burman desighn [PDF]

open access: yes, 2016
زمینه و هدف: این تحقیق به روش تخمیر در بستر جامد به منظور بررسی انواع بسترهای جامد در تولید آنزیم آسپارژیناز توسط سویه ی جداسازی شده از منطقه لاکان استان گیلان از جنس باسیلوس انجام گردید.
Anvari, Masoumeh.   +3 more
core  

Efeito da salinidade sobre a atividade enzimática em solos de região semi-árida do Brasil. [PDF]

open access: yes, 2014
A salinização do solo pode ocorrer por um processo natural ou ser induzida pelo homem (salinização secundária), devido às conseqüências do manejo impróprio da irrigação, má condição de drenagem ou má qualidade da água de irrigação.
PORTO, E. R.   +2 more
core  

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